SLC2A3

Description		solute carrier family 2 member 3
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GO Annotations	Cellular Component	Plasma Membrane Membrane Aggresome Secretory Granule Membrane Specific Granule Membrane Cell Projection Perikaryon Extracellular Exosome Tertiary Granule Membrane Ficolin-1-rich Granule Membrane
	Molecular Function	Fructose Transmembrane Transporter Activity Galactose Transmembrane Transporter Activity Protein Binding D-glucose Binding Transmembrane Transporter Activity Dehydroascorbic Acid Transmembrane Transporter Activity D-glucose Transmembrane Transporter Activity
	Biological Process	Carbohydrate Metabolic Process Fructose Transmembrane Transport Galactose Transmembrane Transport L-ascorbic Acid Metabolic Process D-glucose Import Transmembrane Transport Dehydroascorbic Acid Transport D-glucose Import Across Plasma Membrane Transport Across Blood-brain Barrier D-glucose Transmembrane Transport
Pathways		Cellular hexose transport Vitamin C (ascorbate) metabolism Neutrophil degranulation MECP2 regulates neuronal receptors and channels
Drugs
Diseases
GWAS		Age-related cognitive decline (language) (slope of z-scores) ( 30954325) Waist-to-hip ratio adjusted for BMI x sex interaction ( 26426971)
Interacting Genes		6 interacting genes: CREB3 CREB3L1 GOLGB1 MTNR1A MTNR1B SNTA1
Entrez ID		6515
HPRD ID		00686
Ensembl ID		ENSG00000059804
Uniprot IDs		P11169
PDB IDs		4ZW9 4ZWB 4ZWC 5C65 7CRZ 7SPS 7SPT
Enriched GO Terms of Interacting Partners?		Melatonin Receptor Activity Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Negative Regulation Of Response To Endoplasmic Reticulum Stress Endoplasmic Reticulum Unfolded Protein Response Response To Unfolded Protein Positive Regulation Of Deacetylase Activity Regulation Of Response To Endoplasmic Reticulum Stress Negative Regulation Of Intrinsic Apoptotic Signaling Pathway Protein Localization To Pericentriolar Material Extracellular Matrix Constituent Secretion Positive Regulation Of Circadian Sleep/wake Cycle, Sleep Negative Regulation Of CGMP-mediated Signaling Regulation Of Neuronal Action Potential Negative Regulation Of Intracellular Signal Transduction Negative Regulation Of Transmission Of Nerve Impulse Positive Regulation Of Circadian Sleep/wake Cycle, Non-REM Sleep Syntrophin Complex CCR1 Chemokine Receptor Binding Release From Viral Latency Regulation Of Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Apoptotic Process Positive Regulation Of Transmission Of Nerve Impulse Negative Regulation Of Programmed Cell Death Regulation Of Circadian Sleep/wake Cycle, Non-REM Sleep Response To Endoplasmic Reticulum Stress Negative Regulation Of Apoptotic Signaling Pathway Regulation Of Blood Circulation CAMP Response Element Binding Protein Binding Membrane Nitric-oxide Synthase Binding CAMP Response Element Binding Negative Regulation Of Vasoconstriction Regulation Of CGMP-mediated Signaling Hormone Binding Regulation Of Transmission Of Nerve Impulse Negative Regulation Of Cytosolic Calcium Ion Concentration Dystrophin-associated Glycoprotein Complex Ventricular Cardiac Muscle Cell Action Potential Regulation Of Metal Ion Transport Induction Of Positive Chemotaxis Protein Localization To Centrosome G Protein-coupled Receptor Activity Mating Behavior Negative Regulation Of Signal Transduction Positive Regulation Of Circadian Rhythm Negative Regulation Of Nervous System Process Regulation Of Membrane Potential Regulation Of Circadian Sleep/wake Cycle, Sleep
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