GOLGB1 and INTS5

		GOLGB1	INTS5
Description		golgin B1	integrator complex subunit 5
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Golgi Stack Cis-Golgi Network Cytosol Membrane	Nucleus Nucleoplasm Cytoplasm Cytosol Membrane Nuclear Membrane Integrator Complex INTAC Complex
	Molecular Function	RNA Binding Protein Binding Sequence-specific DNA Binding	Protein Binding
	Biological Process	Regulation Of DNA-templated Transcription Golgi Organization Protein Localization To Pericentriolar Material	SnRNA Processing Regulation Of Transcription Elongation By RNA Polymerase II SnRNA 3'-end Processing RNA Polymerase II Transcription Initiation Surveillance
Pathways		Golgi Associated Vesicle Biogenesis COPI-mediated anterograde transport Signaling by FLT3 fusion proteins Signaling by FLT3 fusion proteins	RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes
Drugs
Diseases
GWAS		Liver enzyme levels (alkaline phosphatase) ( 33972514) Mean reticulocyte volume ( 32888494)	Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		19 interacting genes: ACBD3 ADRB2 BRMS1 CAV2 CEP126 ECPAS ITSN2 MAPK7 NDUFA1 NOD2 PFN2 RNF10 SKIL SLC2A3 SREBF2 UBE2I USO1 USP7 VTI1B	3 interacting genes: CYSRT1 KRTAP10-8 RNF10
Entrez ID		2804	80789
HPRD ID		03933	13883
Ensembl ID		ENSG00000173230	ENSG00000185085
Uniprot IDs		A0A8J9C4H3 E7EU81 Q14789	Q6P9B9
PDB IDs			7CUN 7PKS 7YCX 8RBX 8RBZ 8RC4 8YJB 9EOF 9EP4
Enriched GO Terms of Interacting Partners?		PML Body Vesicle Docking ER To Golgi Transport Vesicle Membrane Vesicle Fusion With Golgi Apparatus Organelle Localization By Membrane Tethering Membrane Docking Vesicle Fusion Cellular Response To Laminar Fluid Shear Stress Organelle Membrane Fusion Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Response To Laminar Fluid Shear Stress Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Signal Transduction Temperature Homeostasis Regulation Of Systemic Arterial Blood Pressure By Norepinephrine-epinephrine Regulation Of RNA Metabolic Process Positive Regulation Of Autophagy Receptor-mediated Endocytosis Regulation Of Autophagy Positive Regulation Of Mini Excitatory Postsynaptic Potential Golgi Apparatus Cytoplasm Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Organelle Fusion Membrane Fusion Cellular Response To Fluid Shear Stress Response To Fluid Shear Stress SUMO Conjugating Enzyme Activity Golgi Vesicle Docking Detection Of Muramyl Dipeptide Muramyl Dipeptide Binding Regulation Of DNA-binding Transcription Factor Activity Negative Regulation Of Cell Communication Negative Regulation Of Signaling Regulation Of Mitophagy
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