BMP10 and RCN1

		BMP10	RCN1
Description		bone morphogenetic protein 10	reticulocalbin 1
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Cytoplasm Cell Surface Z Disc	Endoplasmic Reticulum Endoplasmic Reticulum Lumen
	Molecular Function	Cytokine Activity Hormone Activity Protein Binding Growth Factor Activity Telethonin Binding Receptor Serine/threonine Kinase Binding	Calcium Ion Binding Protein Binding Metal Ion Binding
	Biological Process	Kidney Development Cell Adhesion Heart Development Adult Heart Development Negative Regulation Of Endothelial Cell Migration Regulation Of Cardiac Muscle Hypertrophy Positive Regulation Of Cardiac Muscle Hypertrophy Negative Regulation Of Cardiac Muscle Hypertrophy Positive Regulation Of Gene Expression Negative Regulation Of Cell Growth Negative Regulation Of Cell Migration BMP Signaling Pathway Activin Receptor Signaling Pathway Sarcomere Organization Positive Regulation Of DNA-templated Transcription Positive Regulation Of Multicellular Organismal Process Atrial Cardiac Muscle Tissue Morphogenesis Ventricular Cardiac Muscle Tissue Morphogenesis Ventricular Cardiac Muscle Cell Development Regulation Of Cardiac Muscle Contraction Cardiac Muscle Cell Proliferation Positive Regulation Of Cardiac Muscle Cell Proliferation Positive Regulation Of Sarcomere Organization Heart Trabecula Formation Positive Regulation Of SMAD Protein Signal Transduction Positive Regulation Of Cartilage Development Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Cardiac Muscle Hypertrophy In Response To Stress Positive Regulation Of Cell Proliferation Involved In Heart Morphogenesis	In Utero Embryonic Development Camera-type Eye Development
Pathways		Signaling by BMP Molecules associated with elastic fibres	Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation
Drugs
Diseases
GWAS		Chronic rhinosinusitis ( 33393196)	Apolipoprotein B levels ( 32203549) Basophil count ( 32888494) Blood protein levels ( 30072576) Body mass index ( 28371326) General factor of neuroticism ( 30867560) Major depressive disorder ( 27479909) Metabolite levels (HVA/5-HIAA ratio) ( 23319000) Refractive error ( 32231278)
Interacting Genes		61 interacting genes: ACVR2A ACVR2B APOA5 AQP6 ARL13B BIK BMPR2 BSCL2 BSND CCDC70 CD33 CISD2 CLDN7 COQ9 CPLX4 CREB3L1 DEXI EBP ERP29 FAM209A FCGR1A FCRL4 FFAR2 FKBP7 FNDC9 GGT6 GJB1 GPR152 GPX8 HSD17B13 IL3RA JAGN1 KIR2DL3 KIR3DL1 KLRC1 LRRC25 LRRC4C MGST3 MRPS18B MS4A3 MTIF3 PLPP4 REEP4 SERINC3 SIT1 SLC10A1 SLC10A6 SLC35H1 SLC38A1 SLC4A1 SPAG4 TCTA TMEM14B TMEM31 TMEM45B TMEM86B TMPRSS2 TNFSF14 TNFSF8 TSPAN31 VSIR	19 interacting genes: ASB8 ASPH ATPAF2 ATXN1 CETN3 DCAF11 EFHC1 ENKD1 FAM110A GADD45G LMO1 LMO2 LMO3 LMO4 MYO15B PTEN SGTA SGTB ZNF410
Entrez ID		27302	5954
HPRD ID		09788	04111
Ensembl ID		ENSG00000163217	ENSG00000049449
Uniprot IDs		O95393	Q15293 V9HW95
PDB IDs		6SF1 6SF3 7PPA 7PPB 7PPC 9DPY
Enriched GO Terms of Interacting Partners?		Membrane Activin Receptor Activity, Type II Protein Binding Transmembrane Receptor Protein Serine/threonine Kinase Activity Plasma Membrane Activin Receptor Activity Venous Blood Vessel Development Bile Acid:sodium Symporter Activity Positive Regulation Of Activin Receptor Signaling Pathway Activin Receptor Signaling Pathway Activin Receptor Complex Lymphatic Endothelial Cell Differentiation Fc-gamma Receptor Signaling Pathway Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway BMP Receptor Activity	TRC Complex Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Microtubule Cytoskeleton Organization Microtubule Cytoskeleton Organization Involved In Mitosis Positive Regulation Of RNA Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process DNA-binding Transcription Factor Binding Post-translational Protein Targeting To Endoplasmic Reticulum Membrane Positive Regulation Of Transcription By RNA Polymerase II Cytoskeleton Organization Regulation Of Organ Growth Positive Regulation Of Metabolic Process Microtubule-based Process Positive Regulation Of Macromolecule Biosynthetic Process Protein Targeting To ER Positive Regulation Of Macromolecule Metabolic Process Establishment Of Protein Localization To Endoplasmic Reticulum Positive Regulation Of Biosynthetic Process Establishment Of Mitotic Spindle Orientation Forebrain-midbrain Boundary Formation Pancreatic A Cell Development Establishment Of Mitotic Spindle Localization Negative Regulation Of Synaptic Vesicle Clustering Spindle Organization Spindle Pole Transcription Coregulator Binding
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?