RCN1 and DCAF11

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		RCN1	DCAF11
Description		reticulocalbin 1	DDB1 and CUL4 associated factor 11
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Lumen	Nucleoplasm Cul4-RING E3 Ubiquitin Ligase Complex
	Molecular Function	Calcium Ion Binding Protein Binding Metal Ion Binding	Protein Binding
	Biological Process	In Utero Embryonic Development Camera-type Eye Development	Respiratory System Process Response To Oxidative Stress Memory Gene Expression Protein Ubiquitination Exploration Behavior Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Protein Stabilization Cognition
Pathways		Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation	Neddylation
Drugs
Diseases
GWAS		Apolipoprotein B levels ( 32203549) Basophil count ( 32888494) Blood protein levels ( 30072576) Body mass index ( 28371326) General factor of neuroticism ( 30867560) Major depressive disorder ( 27479909) Metabolite levels (HVA/5-HIAA ratio) ( 23319000) Refractive error ( 32231278)
Interacting Genes		19 interacting genes: ASB8 ASPH ATPAF2 ATXN1 CETN3 DCAF11 EFHC1 ENKD1 FAM110A GADD45G LMO1 LMO2 LMO3 LMO4 MYO15B PTEN SGTA SGTB ZNF410	15 interacting genes: AGR2 CDKN1A CRYAA CUL4B DDB1 FKBP1A GPSM1 PTEN RCN1 SLBP TNNI1 TNNI2 TNS2 TRIM55 TRIM63
Entrez ID		5954	80344
HPRD ID		04111	18297
Ensembl ID		ENSG00000049449	ENSG00000100897
Uniprot IDs		Q15293 V9HW95	B3KSW2 Q59GN6 Q8TEB1
PDB IDs
Enriched GO Terms of Interacting Partners?		TRC Complex Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Microtubule Cytoskeleton Organization Microtubule Cytoskeleton Organization Involved In Mitosis Positive Regulation Of RNA Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process DNA-binding Transcription Factor Binding Post-translational Protein Targeting To Endoplasmic Reticulum Membrane Positive Regulation Of Transcription By RNA Polymerase II Cytoskeleton Organization Regulation Of Organ Growth Positive Regulation Of Metabolic Process Microtubule-based Process Positive Regulation Of Macromolecule Biosynthetic Process Protein Targeting To ER Positive Regulation Of Macromolecule Metabolic Process Establishment Of Protein Localization To Endoplasmic Reticulum Positive Regulation Of Biosynthetic Process Establishment Of Mitotic Spindle Orientation Forebrain-midbrain Boundary Formation Pancreatic A Cell Development Establishment Of Mitotic Spindle Localization Negative Regulation Of Synaptic Vesicle Clustering Spindle Organization Spindle Pole Transcription Coregulator Binding	Response To UV Cul4B-RING E3 Ubiquitin Ligase Complex Troponin Complex Cellular Response To UV Cul4A-RING E3 Ubiquitin Ligase Complex UV-damage Excision Repair Spindle Assembly Involved In Female Meiosis Meiotic Spindle Assembly Cellular Response To Light Stimulus Response To Light Stimulus Regulation Of Mitotic Cell Cycle Phase Transition Meiotic Spindle Organization Protein Refolding Cul4-RING E3 Ubiquitin Ligase Complex Negative Regulation Of Vascular Associated Smooth Muscle Cell Proliferation Negative Regulation Of Phosphate Metabolic Process Molecular Function Inhibitor Activity Regulation Of G1/S Transition Of Mitotic Cell Cycle Cellular Response To Radiation Skeletal Muscle Contraction Response To Radiation Regulation Of Cell Cycle Phase Transition Regulation Of Cell Cycle G1/S Phase Transition Response To Electrical Stimulus Developmental Process Cardiac Muscle Contraction Muscle Contraction Ventricular Cardiac Muscle Tissue Morphogenesis Regulation Of Mitotic Cell Cycle Macrolide Binding Negative Regulation Of Synaptic Vesicle Clustering Negative Regulation Of Smooth Muscle Cell Proliferation Positive Regulation Of Catabolic Process Regulation Of System Process Cardiac Muscle Tissue Morphogenesis Negative Regulation Of Cell Cycle G1/S Phase Transition PCNA-p21 Complex Negative Regulation Of Cardiac Muscle Tissue Regeneration Regulation Of Growth Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Protein Modification Process Damaged DNA Binding Protein Ubiquitination Cytoplasmic Side Of Membrane Regulation Of Muscle System Process Ryanodine Receptor Complex Phosphatidylinositol-3,4-bisphosphate 3-phosphatase Activity Negative Regulation Of Keratinocyte Migration Inositol-1,3,4,5-tetrakisphosphate 3-phosphatase Activity Inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase Activity
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