PDLIM3 and PALLD

Number of citations of the paper that reports this interaction (PubMedID 23414517)
48

Data Source:
BioGRID (two hybrid)

		PDLIM3	PALLD
Description		PDZ and LIM domain 3	palladin, cytoskeletal associated protein
Image		No pdb structure
GO Annotations	Cellular Component	Stress Fiber Cytoplasm Cytosol Adherens Junction Actin Cytoskeleton Z Disc Filamentous Actin	Stress Fiber Ruffle Podosome Nucleus Cytoplasm Mitochondrion Cytosol Cytoskeleton Actin Filament Plasma Membrane Focal Adhesion Actin Cytoskeleton Z Disc Lamellipodium Axon Growth Cone Cell Projection Excitatory Synapse Anchoring Junction
	Molecular Function	Actin Binding Protein Binding Cytoskeletal Protein Binding Structural Constituent Of Muscle Metal Ion Binding Muscle Alpha-actinin Binding	Actin Binding Protein Binding Muscle Alpha-actinin Binding Cell-cell Adhesion Mediator Activity
	Biological Process	Actin Filament Organization Heart Development Actin Cytoskeleton Organization Muscle Structure Development	Keratinocyte Development Epithelial Cell Morphogenesis Cytoskeleton Organization Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Axon Guidance Cell Migration Actin Cytoskeleton Organization Dendrite Self-avoidance
Pathways
Drugs
Diseases
GWAS			Bacteremia ( 27236921) Coronary artery disease ( 29212778 33020668) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Non-alcoholic fatty liver disease histology (AST) ( 20708005) Pulse pressure ( 27841878 28135244 30578418) Response to iloperidone treatment (QT prolongation) ( 18521091) Soluble receptor for advanced glycation end-product levels ( 26915486) Systolic blood pressure ( 30578418) Vein graft stenosis in coronary artery bypass grafting ( 25881214)
Interacting Genes		11 interacting genes: ABCA1 ACTN2 FHL1 MYOT MYOZ2 MYOZ3 MYPN PALLD RANBP2 RHOU RYR1	10 interacting genes: ACTN1 ACTN2 CDC42 EZR ITGB5 LIG4 PDLIM3 SORBS2 SRPK2 SUMO2
Entrez ID		27295	23022
HPRD ID		08388	09731
Ensembl ID		ENSG00000154553	ENSG00000129116
Uniprot IDs		A0A087WYF8 A0A2U3TZH4 Q53GG5	A0A994J7A4 B2RTX2 Q8WX93
PDB IDs			2DM2 2DM3
Enriched GO Terms of Interacting Partners?		Z Disc FATZ Binding Actin Binding Actin Cytoskeleton Actin Cytoskeleton Organization Sarcomere Organization Actin Filament-based Process Sarcomere Channel Activator Activity Telethonin Binding Muscle Alpha-actinin Binding Actomyosin Structure Organization Dendrite Self-avoidance Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules I Band Focal Adhesion Positive Regulation Of Potassium Ion Transport Cell-cell Adhesion Mediator Activity Sarcoplasmic Reticulum Membrane Structural Constituent Of Muscle Cytoskeleton Organization Axon Guidance Cell-cell Adhesion Via Plasma-membrane Adhesion Molecules Neuron Projection Guidance Podosome Neuron Recognition Organelle Organization Sphingolipid Floppase Activity Actin Filament Uncapping Regulation Of Intracellular Transport Cytoskeletal Protein Binding Sarcoplasmic Reticulum Striated Muscle Cell Development Response To Vitamin B3 Positive Regulation Of High-density Lipoprotein Particle Assembly Apolipoprotein A-I Receptor Activity Titin Z Domain Binding Cytoplasmic Periphery Of The Nuclear Pore Complex Ryanodine Receptor Complex Regulation Of Potassium Ion Transport Actin Filament Regulation Of High-density Lipoprotein Particle Assembly Muscle Cell Development Phospholipase C-activating Angiotensin-activated Signaling Pathway Ryanodine-sensitive Calcium-release Channel Activity Skeletal Muscle Fiber Adaptation Cell Adhesion Plasma Membrane Bounded Cell Projection Organization Axon Phosphatidylserine Floppase Activity	Actin Filament-based Process Cytoskeletal Protein Binding Focal Adhesion Actin Cytoskeleton Organization Actin Filament Organization Cytoskeleton Organization Organelle Organization Actin Cytoskeleton Z Disc Structural Constituent Of Muscle Supramolecular Fiber Organization Actin Filament Bundle Assembly Actin Filament Bundle Organization Filopodium Actin Filament Actin Binding Pseudopodium Postsynaptic Actin Cytoskeleton Organization Establishment Of Epithelial Cell Apical/basal Polarity Postsynaptic Cytoskeleton Organization Integrin Binding Establishment Of Apical/basal Cell Polarity Filopodium Assembly Polarized Epithelial Cell Differentiation Establishment Of Monopolar Cell Polarity Establishment Or Maintenance Of Monopolar Cell Polarity Focal Adhesion Assembly Establishment Of Epithelial Cell Polarity Actin Filament Binding Glutamatergic Synapse Cell-substrate Junction Assembly Cell-substrate Junction Organization Cellular Developmental Process Postsynapse Organization Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Cell Projection Cell Junction Assembly Establishment Or Maintenance Of Apical/basal Cell Polarity Cortical Actin Cytoskeleton Sarcomere Brush Border Actin Filament Uncapping Establishment Of Integrated Proviral Latency Platelet Alpha Granule Lumen Cell Differentiation Anatomical Structure Formation Involved In Morphogenesis Regulation Of Actin Cytoskeleton Organization Cell Adhesion Cellular Component Assembly Structural Constituent Of Postsynapse
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