PALLD and ITGB5

Number of citations of the paper that reports this interaction (PMID 16355270)
9

Data Source:
HPRD (two hybrid)

		PALLD	ITGB5
Gene Name		palladin, cytoskeletal associated protein	integrin, beta 5
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Ruffle Nucleus Cytoplasm Mitochondrion Actin Filament Plasma Membrane Focal Adhesion Actin Cytoskeleton Z Disc Lamellipodium	Plasma Membrane Focal Adhesion Cell Surface Cell Leading Edge Integrin Alphav-beta5 Complex Receptor Complex Phagocytic Vesicle Extracellular Vesicular Exosome
	Molecular Function	Actin Binding Protein Binding Muscle Alpha-actinin Binding	Receptor Activity Integrin Binding Protein Binding
	Biological Process	Cytoskeleton Organization	Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-dependent Muscle Contraction Cell-matrix Adhesion Transforming Growth Factor Beta Receptor Signaling Pathway Integrin-mediated Signaling Pathway Extracellular Matrix Organization Endodermal Cell Differentiation Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I Stress Fiber Assembly Epithelial Cell-cell Adhesion
Pathways			Elastic fibre formation Smooth Muscle Contraction Non-integrin membrane-ECM interactions Molecules associated with elastic fibres Syndecan interactions ECM proteoglycans Integrin cell surface interactions Class I MHC mediated antigen processing & presentation Antigen processing-Cross presentation Cross-presentation of particulate exogenous antigens (phagosomes) Adaptive Immune System
Drugs
Diseases
GWAS		Non-alcoholic fatty liver disease histology (AST) ( 20708005) Response to iloperidone treatment (QT prolongation) ( 18521091)
Protein-Protein Interactions		6 interactors: ACTN1 ACTN2 EZR ITGB5 LIG4 SORBS2	34 interactors: ANXA5 CYR61 DAB1 DAB2 DOK1 EHMT2 EPS8 EWSR1 FHL2 FLNA GNB2L1 ITGA5 ITGAV ITGB3BP KRT40 KRTAP10-8 KRTAP10-9 LTBP1 LTBP3 MTUS2 MYO10 NOTCH2NL NUMB P2RY2 PAK4 PALLD PIAS2 PPARD PTK2 SNTA1 SRSF9 TLN1 TNS2 ZBTB17
Entrez ID		23022	3693
HPRD ID		09731	00949
Ensembl ID		ENSG00000129116	ENSG00000082781
Uniprot IDs		B2RTX2 Q8WX93	L7RT22 P18084
PDB IDs		2DM2 2DM3
Enriched GO Terms of Interacting Partners?		Cell Adhesion Actin Filament-based Process Actin Filament Organization Actin Filament Bundle Assembly Actin Cytoskeleton Organization Cell-matrix Adhesion Cell-substrate Adhesion Focal Adhesion Assembly Adherens Junction Assembly Cell-substrate Junction Assembly Cytoskeleton Organization Platelet Degranulation Adherens Junction Organization Single Organismal Cell-cell Adhesion Organelle Organization DNA Ligation Involved In DNA Recombination Cell Activation Cellular Component Assembly Protein Localization To Tight Junction Platelet Activation Cell Junction Assembly Cell-cell Junction Organization Membrane To Membrane Docking Muscle Contraction Lagging Strand Elongation Pro-B Cell Differentiation Microspike Assembly Muscle System Process Establishment Of Integrated Proviral Latency Negative Regulation Of Protein Localization To Cell Surface Protein Localization To Cell Junction Cell Projection Assembly Immunoglobulin V(D)J Recombination Establishment Of Viral Latency T Cell Receptor V(D)J Recombination Negative Regulation Of Potassium Ion Transmembrane Transporter Activity DNA Ligation Involved In DNA Repair Leukocyte Cell-cell Adhesion Cytoskeletal Anchoring At Plasma Membrane Exocytosis Lymphoid Progenitor Cell Differentiation Positive Regulation Of Potassium Ion Transmembrane Transporter Activity Extracellular Matrix Organization Extracellular Structure Organization Negative Regulation Of Potassium Ion Transmembrane Transport DNA Ligation Stress Fiber Assembly Microvillus Assembly Vesicle-mediated Transport Regulation Of Apoptotic Process	Signaling Cell Communication Signal Transduction Regulation Of Cellular Process Cellular Response To Stimulus Regulation Of Cellular Component Movement Positive Regulation Of Cell Migration Positive Regulation Of Cell Motility Locomotion Positive Regulation Of Cellular Component Movement Positive Regulation Of Locomotion Anatomical Structure Morphogenesis Response To Stimulus Regulation Of Cell Migration Wound Healing Cell Development Regulation Of Cell Motility Movement Of Cell Or Subcellular Component Regulation Of Locomotion Response To Wounding Cell Morphogenesis Involved In Differentiation Negative Regulation Of Cell Death Positive Regulation Of Protein Phosphorylation Cell Differentiation Extracellular Matrix Organization Extracellular Structure Organization Cell Migration Regulation Of Apoptotic Process Cell Surface Receptor Signaling Pathway Chemotaxis Positive Regulation Of Phosphorylation Axon Guidance Multicellular Organismal Development Regulation Of Cell Adhesion Cell Motility Positive Regulation Of Protein Modification Process Regulation Of Cell Death Regulation Of Signal Transduction Negative Regulation Of Apoptotic Process Blood Coagulation Negative Regulation Of Programmed Cell Death Hemostasis Developmental Process Anatomical Structure Development Apoptotic Process Positive Regulation Of Protein Kinase Activity Programmed Cell Death Positive Regulation Of Kinase Activity Regulation Of Protein Kinase Activity Cell Morphogenesis
Tagcloud ?			concurrently ctsk dc dendritic elucidated enhancer imply isoform itga2 itga5 itgav itgb1 itgb3 microphthalmia mitf multinucleated nfatc1 osteoclast osteoclastogenesis osteoclasts potentiated rankl raw264 resembled stamp tartrate tgf transforming transmembrane
Tagcloud (Difference) ?			concurrently ctsk dc dendritic elucidated enhancer imply isoform itga2 itga5 itgav itgb1 itgb3 microphthalmia mitf multinucleated nfatc1 osteoclast osteoclastogenesis osteoclasts potentiated rankl raw264 resembled stamp tartrate tgf transforming transmembrane
Tagcloud (Intersection) ?