PALLD

Gene Name		palladin, cytoskeletal associated protein
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Gene Ontology Annotations	Cellular Component	Ruffle Nucleus Cytoplasm Mitochondrion Actin Filament Plasma Membrane Focal Adhesion Actin Cytoskeleton Z Disc Lamellipodium
	Molecular Function	Actin Binding Protein Binding Muscle Alpha-actinin Binding
	Biological Process	Cytoskeleton Organization
Pathways
Drugs
Diseases
GWAS		Non-alcoholic fatty liver disease histology (AST) ( 20708005) Response to iloperidone treatment (QT prolongation) ( 18521091)
Protein-protein Interactions		6 interactors: ACTN1 ACTN2 EZR ITGB5 LIG4 SORBS2
Entrez ID		23022
HPRD ID		09731
Ensembl ID		ENSG00000129116
Uniprot IDs		B2RTX2 Q8WX93
PDB IDs		2DM2 2DM3
Enriched GO Terms of Interacting Partners?		Cell Adhesion Actin Filament-based Process Actin Filament Organization Actin Filament Bundle Assembly Actin Cytoskeleton Organization Cell-matrix Adhesion Cell-substrate Adhesion Focal Adhesion Assembly Adherens Junction Assembly Cell-substrate Junction Assembly Cytoskeleton Organization Platelet Degranulation Adherens Junction Organization Single Organismal Cell-cell Adhesion Organelle Organization DNA Ligation Involved In DNA Recombination Cell Activation Cellular Component Assembly Protein Localization To Tight Junction Platelet Activation Cell Junction Assembly Cell-cell Junction Organization Membrane To Membrane Docking Muscle Contraction Lagging Strand Elongation Pro-B Cell Differentiation Microspike Assembly Muscle System Process Establishment Of Integrated Proviral Latency Negative Regulation Of Protein Localization To Cell Surface Protein Localization To Cell Junction Cell Projection Assembly Immunoglobulin V(D)J Recombination Establishment Of Viral Latency T Cell Receptor V(D)J Recombination Negative Regulation Of Potassium Ion Transmembrane Transporter Activity DNA Ligation Involved In DNA Repair Leukocyte Cell-cell Adhesion Cytoskeletal Anchoring At Plasma Membrane Exocytosis Lymphoid Progenitor Cell Differentiation Positive Regulation Of Potassium Ion Transmembrane Transporter Activity Extracellular Matrix Organization Extracellular Structure Organization Negative Regulation Of Potassium Ion Transmembrane Transport DNA Ligation Stress Fiber Assembly Microvillus Assembly Vesicle-mediated Transport Regulation Of Apoptotic Process
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