PDLIM3 and MYOZ3

Number of citations of the paper that reports this interaction (PubMedID 23414517)
48

Data Source:
BioGRID (two hybrid)

		PDLIM3	MYOZ3
Description		PDZ and LIM domain 3	myozenin 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Stress Fiber Cytoplasm Cytosol Adherens Junction Actin Cytoskeleton Z Disc Filamentous Actin	Cytoplasm Actin Cytoskeleton Z Disc
	Molecular Function	Actin Binding Protein Binding Cytoskeletal Protein Binding Structural Constituent Of Muscle Metal Ion Binding Muscle Alpha-actinin Binding	Actin Binding Protein Binding Telethonin Binding FATZ Binding
	Biological Process	Actin Filament Organization Heart Development Actin Cytoskeleton Organization Muscle Structure Development
Pathways
Drugs
Diseases
GWAS			Cholangiocarcinoma in primary sclerosing cholangitis ( 28779025) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908)
Interacting Genes		11 interacting genes: ABCA1 ACTN2 FHL1 MYOT MYOZ2 MYOZ3 MYPN PALLD RANBP2 RHOU RYR1	71 interacting genes: ABI2 ACTN1 ACTN2 AKIRIN2 ASPG ATOSB ATXN1L BAG4 BCAS2 C10orf55 CCDC57 CIMIP2B CREM CRLF3 DAZAP2 DMRT3 EFS ENKD1 EXOC8 FAM168B FHL3 FHL5 FLNC GCM2 GOLGA6A GOLGA6L9 HSF2BP KANK2 KRT34 KRT36 KRT75 KRTAP19-5 KRTAP19-6 KRTAP6-1 KRTAP7-1 KRTAP8-1 KYNU LDB3 LENG8 LMO2 LMO3 LMO4 LONRF1 MAPK6 MORN3 MRPL38 MYO15B NEK6 NUTF2 PDLIM3 PITX1 PM20D2 PPP3CA PPP3CB PRDM6 PSMB4 PTK6 RINT1 RNF125 RUSC1 SPMIP5 TBX15 TCAP TEKT4 TRAPPC6A TSC1 TSSK3 UFSP1 YPEL3 ZNF620 ZNF688
Entrez ID		27295	91977
HPRD ID		08388	17624
Ensembl ID		ENSG00000154553	ENSG00000164591
Uniprot IDs		A0A087WYF8 A0A2U3TZH4 Q53GG5	Q8TDC0
PDB IDs
Enriched GO Terms of Interacting Partners?		Z Disc FATZ Binding Actin Binding Actin Cytoskeleton Actin Cytoskeleton Organization Sarcomere Organization Actin Filament-based Process Sarcomere Channel Activator Activity Telethonin Binding Muscle Alpha-actinin Binding Actomyosin Structure Organization Dendrite Self-avoidance Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules I Band Focal Adhesion Positive Regulation Of Potassium Ion Transport Cell-cell Adhesion Mediator Activity Sarcoplasmic Reticulum Membrane Structural Constituent Of Muscle Cytoskeleton Organization Axon Guidance Cell-cell Adhesion Via Plasma-membrane Adhesion Molecules Neuron Projection Guidance Podosome Neuron Recognition Organelle Organization Sphingolipid Floppase Activity Actin Filament Uncapping Regulation Of Intracellular Transport Cytoskeletal Protein Binding Sarcoplasmic Reticulum Striated Muscle Cell Development Response To Vitamin B3 Positive Regulation Of High-density Lipoprotein Particle Assembly Apolipoprotein A-I Receptor Activity Titin Z Domain Binding Cytoplasmic Periphery Of The Nuclear Pore Complex Ryanodine Receptor Complex Regulation Of Potassium Ion Transport Actin Filament Regulation Of High-density Lipoprotein Particle Assembly Muscle Cell Development Phospholipase C-activating Angiotensin-activated Signaling Pathway Ryanodine-sensitive Calcium-release Channel Activity Skeletal Muscle Fiber Adaptation Cell Adhesion Plasma Membrane Bounded Cell Projection Organization Axon Phosphatidylserine Floppase Activity	Z Disc Intermediate Filament Muscle Cell Development Cytoskeletal Protein Binding Cytoskeleton Organization Protein Binding Titin Z Domain Binding Sarcomere Organization Pseudopodium FATZ Binding Calmodulin-dependent Protein Phosphatase Activity Striated Muscle Cell Development Negative Regulation Of Calcium Ion Import Across Plasma Membrane Calcineurin Complex Organelle Organization Actin Filament Stress Fiber Cell Projection Protein Serine/threonine Phosphatase Complex
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