RND2 and UBXN11

Number of citations of the paper that reports this interaction (PubMedID 11940653)
29

Data Source:
HPRD (two hybrid, in vitro)

		RND2	UBXN11
Description		Rho family GTPase 2	UBX domain protein 11
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Acrosomal Membrane Cytosol Plasma Membrane Membrane Cytoplasmic Vesicle	Cytoplasm Cytosol Cytoskeleton
	Molecular Function	Nucleotide Binding GTPase Activity Protein Binding GTP Binding Protein Kinase Binding	Protein Binding Ubiquitin Binding
	Biological Process	Actin Filament Organization Signal Transduction Small GTPase-mediated Signal Transduction Regulation Of Actin Cytoskeleton Organization Collateral Sprouting Positive Regulation Of Collateral Sprouting	Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Pathways		RND2 GTPase cycle	RND3 GTPase cycle RND2 GTPase cycle RND1 GTPase cycle
Drugs
Diseases
GWAS		Coronary artery disease ( 29212778)	Monocyte percentage of white cells ( 32888494) Obesity-related traits ( 23251661) Platelet count ( 32888494)
Interacting Genes		5 interacting genes: FNBP1 MEOX2 RACGAP1 UBXN11 VPS4A	34 interacting genes: C14orf119 CFAP206 EIF4E EIF4E2 ENKD1 HGS IL16 LENG1 NEK6 PPM1K PRKAA1 PRKAB2 PRPF18 PRPF31 PRR35 PSMA1 RHOBTB3 RND1 RND2 RND3 RNF213 SCNM1 SH2D4A SNRPB TCEANC TLE5 TRAF2 TTC23 USHBP1 VCP VPS9D1 WDR25 ZFYVE9 ZGPAT
Entrez ID		8153	91544
HPRD ID		03332	10245
Ensembl ID		ENSG00000108830	ENSG00000158062
Uniprot IDs		P52198	Q5T124
PDB IDs
Enriched GO Terms of Interacting Partners?		Spindle Cytoskeleton Flemming Body Cytokinetic Process Microtubule Nucleator Activity Actomyosin Contractile Ring Contraction Late Endosome To Lysosome Transport Via Multivesicular Body Sorting Pathway Late Endosomal Microautophagy Cytoskeleton-dependent Cytokinesis Regulation Of Cytokinesis Contractile Ring Contraction Positive Regulation Of Viral Budding Via Host ESCRT Complex Centralspindlin Complex Somite Specification Polar Microtubule Mitotic Cytokinesis Checkpoint Signaling Regulation Of Cell Division Midbody Ubiquitin-independent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Actomyosin Contractile Ring Assembly ATP-dependent Protein Disaggregase Activity Vesicle Uncoating Endosome To Lysosome Transport Via Multivesicular Body Sorting Pathway Negative Regulation Of Cytokinesis Mitotic Nuclear Membrane Reassembly ESCRT III Complex Disassembly ESCRT Complex Disassembly Mitotic Spindle Midzone Assembly Gamma-tubulin Ring Complex Gamma-tubulin Complex ATPase Complex Sulfate Transmembrane Transport Spindle Midzone Assembly Cytoplasm Segment Specification Somite Development Microtubule Mitotic Spindle Microtubule Lipid Binding Endosomal Vesicle Fusion Viral Budding From Plasma Membrane Negative Regulation Of Cell Division Vacuolar Membrane Positive Regulation Of Exosomal Secretion Late Endosome To Lysosome Transport Regulation Of Exosomal Secretion Meiotic Spindle Organization Pericentriolar Material Intracellular Cholesterol Transport Viral Budding Via Host ESCRT Complex	Nuclear Speck MRNA Cap Binding SnRNP Binding AMP-activated Protein Kinase Activity U4/U6 X U5 Tri-snRNP Complex Protein Binding Protein Kinase Binding RNA Cap Binding RNA 7-methylguanosine Cap Binding Eukaryotic Translation Initiation Factor 4F Complex Nucleotide-activated Protein Kinase Complex U4 SnRNP Ubiquitin Protein Ligase Binding Spliceosomal Complex Organelle Disassembly
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