SLC39A2 and EMC6

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SLC39A2	EMC6
Description		solute carrier family 39 member 2	ER membrane protein complex subunit 6
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Cytoplasmic Vesicle Cytoplasmic Ribonucleoprotein Granule	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane EMC Complex Omegasome Membrane
	Molecular Function	Zinc Ion Transmembrane Transporter Activity Protein Binding Metal Ion Transmembrane Transporter Activity	Protein Binding Membrane Insertase Activity
	Biological Process	Monoatomic Ion Transport Zinc Ion Transport Metal Ion Transport Keratinocyte Differentiation Transmembrane Transport Cadmium Ion Transmembrane Transport Zinc Ion Transmembrane Transport	Autophagosome Assembly Protein Insertion Into ER Membrane By Stop-transfer Membrane-anchor Sequence Tail-anchored Membrane Protein Insertion Into ER Membrane
Pathways		Zinc influx into cells by the SLC39 gene family
Drugs
Diseases
GWAS
Interacting Genes		52 interacting genes: AQP1 AQP6 ARL13B ARLN BCL2L2 BTN2A2 C3orf52 CD79A CLCA4 CNR2 COL4A5 COMT CREB3L1 CXCR2 CYB561 EHHADH EMC6 FAM209A FCER1G FXYD3 FXYD6 GJA8 GPR152 GPR42 KCNAB1 KCNAB2 LY6G6C MFSD6 MS4A13 PLN PNLIPRP1 SEC22A SLC18A1 SLC30A2 SLC30A8 SLC39A1 SLC39A9 SLC66A1 SLC7A1 SSMEM1 ST6GAL2 STATH TMEM107 TMEM14B TMEM229B TMEM237 TMEM54 TMEM60 TMEM86A TRHR UPK1B YIPF6	21 interacting genes: AQP6 AQP9 CD79A CREB3 EBP ELOVL4 ERGIC3 FAM209A FFAR2 MMD MUC1 PDZK1IP1 SLC10A1 SLC10A6 SLC35H1 SLC39A2 SLC71A2 SLC7A1 TLCD4 TMEM14B TMEM237
Entrez ID		29986	83460
HPRD ID		15385	14529
Ensembl ID		ENSG00000165794	ENSG00000127774
Uniprot IDs		Q9NP94	Q9BV81
PDB IDs			6WW7 6Z3W 7ADO 7ADP 8EOI 8J0N 8J0O 8S9S 9C7V
Enriched GO Terms of Interacting Partners?		Membrane Transmembrane Transport Monoatomic Ion Transport Zinc Ion Transmembrane Transporter Activity Inorganic Ion Transmembrane Transport Zinc Ion Transport Zinc Ion Transmembrane Transport Metal Ion Transport Monoatomic Cation Transport Monoatomic Ion Transmembrane Transport Lysine Transport Potassium Ion Transport Inorganic Cation Transmembrane Transport Protein Binding Plasma Membrane Carbon Dioxide Transmembrane Transporter Activity Carbon Dioxide Transmembrane Transport L-lysine Transmembrane Transporter Activity L-histidine Transmembrane Transporter Activity L-histidine Transmembrane Transport Zinc:proton Antiporter Activity Monoamine Transport Intracellular Zinc Ion Homeostasis Monoatomic Cation Transmembrane Transport L-lysine Transmembrane Transport Organic Cation Transport Ion Channel Regulator Activity Renal Water Transport Norepinephrine Transport Positive Regulation Of Sodium Ion Export Across Plasma Membrane Neural Tube Patterning Channel Activity Ammonium Channel Activity Regulation Of Monoatomic Ion Transmembrane Transport Basic Amino Acid Transmembrane Transporter Activity L-arginine Transmembrane Transporter Activity Ammonium Transmembrane Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I Response To Zinc Ion Aromatic Amino Acid Transport Zinc Ion Import Into Organelle L-arginine Transmembrane Transport Transport Vesicle Membrane Serotonin Transport Azole Transmembrane Transport Juxtaparanode Region Of Axon Alcohol Dehydrogenase (NADP+) Activity External Side Of Plasma Membrane Water Channel Activity Carbon Dioxide Transport	Membrane Bile Acid:sodium Symporter Activity Transmembrane Transport Water Channel Activity Bile Acid And Bile Salt Transport Nitrate Transmembrane Transporter Activity One-carbon Compound Transport Fluid Transport Water Transport Channel Activity Organic Hydroxy Compound Transport Pyrimidine Nucleobase Transmembrane Transporter Activity Detoxification Of Arsenic-containing Substance Organic Anion Transport Positive Regulation Of Deacetylase Activity Cholesterol-5,6-oxide Hydrolase Activity Sodium-dependent Organic Anion Transmembrane Transporter Activity Sodium-dependent Organic Anion Transport
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