NFU1 and ZNF688

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		NFU1	ZNF688
Description		NFU1 iron-sulfur cluster scaffold	zinc finger protein 688
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Mitochondrion Mitochondrial Matrix Cytosol	Nucleus
	Molecular Function	Iron Ion Binding Protein Binding Metal Ion Binding Iron-sulfur Cluster Binding 2 Iron, 2 Sulfur Cluster Binding 4 Iron, 4 Sulfur Cluster Binding	DNA Binding DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Iron-sulfur Cluster Assembly Protein Maturation	Regulation Of DNA-templated Transcription
Pathways		Protein lipoylation	Generic Transcription Pathway
Drugs
Diseases
GWAS
Interacting Genes		23 interacting genes: AGTRAP APOC1 APOC2 APOC4 CALCOCO2 CIDEB CMTM5 COIL DESI2 EPM2A FKBP7 HIRA HSPB1 MDK MORN3 NOA1 RHBDD2 SDCBP2 SH3BP4 TFIP11 TRIM23 ZNF688 ZSCAN5A	111 interacting genes: ABI2 AIRIM ANKRD11 BEND5 BLZF1 BOLA2 BOLA2B CADPS CALCOCO2 CARD9 CATSPER1 CBY2 CCDC102B CCDC136 CCDC33 CCDC57 CCNC CDKN2D CDR2L CEP44 CEP70 CEP72 CIB3 CRX DEF6 EHMT2 FAM90A1 FBXO7 FCHO1 FHL5 GEM GLYCTK GMPPA GOLGA2 GPANK1 GPRASP2 HMBOX1 HNRNPK HOMEZ HOXA1 HSF2BP IGFN1 IHO1 KHDRBS2 KHDRBS3 KIFC3 KRT13 KRT15 KRT31 KRT40 KRTAP10-3 KRTAP10-9 KRTAP12-2 KRTAP4-2 LDOC1 LMO1 LMO2 MAGED1 MDFI MEOX2 MID2 MIPOL1 MKRN3 MYOZ3 NCK2 NEK6 NFU1 NOTCH2NLA OSTF1 PCBD1 PFKFB1 PHF1 PIH1D2 PLSCR1 PNMA1 PNMA2 POLR1C PSMA3 PSMB1 PSTPIP1 RCOR3 REL RFX6 RINT1 RPGRIP1 SCNM1 SMARCB1 SPAG5 SSX2IP TADA2A TCEANC TCF12 TCF4 TCP11 TEKT4 TENT5B TLE5 TMCC2 TNS2 TRAF1 TRAF2 TRAF4 TRIM23 TRIM27 TRIP6 TTC19 USHBP1 WWP2 ZC4H2 ZGPAT ZNF330
Entrez ID		27247	146542
HPRD ID		12163	14070
Ensembl ID		ENSG00000169599	ENSG00000229809
Uniprot IDs		Q9UMS0	A0A0S2Z5X4 A0A0S2Z633 P0C7X2
PDB IDs		2LTM 2M5O
Enriched GO Terms of Interacting Partners?		High-density Lipoprotein Particle Very-low-density Lipoprotein Particle Acylglycerol Homeostasis Negative Regulation Of Very-low-density Lipoprotein Particle Clearance Chylomicron Remnant Clearance Triglyceride-rich Lipoprotein Particle Clearance Triglyceride Homeostasis Regulation Of Triglyceride Metabolic Process Regulation Of Phospholipid Catabolic Process Lipase Inhibitor Activity Positive Regulation Of Autophagy Very-low-density Lipoprotein Particle Assembly Regulation Of Autophagy Chylomicron Phospholipid Efflux Negative Regulation Of Lipoprotein Particle Clearance Identical Protein Binding Negative Regulation Of Cholesterol Transport Plasma Lipoprotein Particle Assembly Protein-lipid Complex Assembly Plasma Lipoprotein Particle Clearance Lipid Transport Cholesterol Efflux Positive Regulation Of Catabolic Process Negative Regulation Of Receptor-mediated Endocytosis Lipoprotein Metabolic Process Lipid Storage Regulation Of Phospholipid Metabolic Process Plasma Lipoprotein Particle Remodeling Protein-containing Complex Remodeling Negative Regulation Of Lipid Transport Negative Regulation Of Phosphatidylcholine Catabolic Process Negative Regulation Of Protein Kinase C Signaling Defecation HIR Complex Negative Regulation Of Hydrolase Activity Carbohydrate Phosphatase Activity Lipid Homeostasis Regulation Of Fatty Acid Biosynthetic Process Positive Regulation Of Very-low-density Lipoprotein Particle Remodeling Spliceosomal Complex Disassembly	Protein Binding Identical Protein Binding Keratin Filament Nucleus Intermediate Filament Signaling Adaptor Activity Cytoskeleton Thioesterase Binding Transcription Coactivator Activity Microtubule Organizing Center Organization
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