NFU1 and EPM2A

Number of citations of the paper that reports this interaction (PMID 12915448)
6

Data Source:
HPRD (in vivo, two hybrid, in vitro)

		NFU1	EPM2A
Gene Name		NFU1 iron-sulfur cluster scaffold	epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Mitochondrion Cytosol	Nucleus Cytoplasm Endoplasmic Reticulum Cytosol Polysome Plasma Membrane
	Molecular Function	Iron Ion Binding Protein Binding 4 Iron, 4 Sulfur Cluster Binding	Phosphatidylinositol-4,5-bisphosphate 5-phosphatase Activity Protein Serine/threonine Phosphatase Activity Protein Tyrosine Phosphatase Activity Protein Binding Protein Tyrosine/serine/threonine Phosphatase Activity Carbohydrate Phosphatase Activity Starch Binding
	Biological Process	Iron-sulfur Cluster Assembly	Carbohydrate Metabolic Process Glycogen Metabolic Process Glycogen Biosynthetic Process Glucose Metabolic Process Protein Dephosphorylation Autophagy Nervous System Development Pathogenesis Peptidyl-tyrosine Dephosphorylation Small Molecule Metabolic Process Inositol Phosphate Dephosphorylation Habituation
Pathways			Glucose metabolism Glycogen synthesis Myoclonic epilepsy of Lafora Glycogen storage diseases Metabolism of carbohydrates
Drugs
Diseases
GWAS
Protein-Protein Interactions		8 interactors: AGTRAP CALCOCO2 EPM2A HIRA NOA1 SH3BP4 TFIP11 TRIM23	7 interactors: EPM2AIP1 NFU1 NHLRC1 PPP1R3D PRKAA1 PRKAA2 PRKAB2
Entrez ID		27247	7957
HPRD ID		12163	06345
Ensembl ID		ENSG00000169599	ENSG00000112425
Uniprot IDs		Q9UMS0	O95278
PDB IDs		2LTM 2M5O
Enriched GO Terms of Interacting Partners?			Regulation Of Generation Of Precursor Metabolites And Energy Energy Reserve Metabolic Process Regulation Of Carbohydrate Metabolic Process Response To Insulin Energy Derivation By Oxidation Of Organic Compounds Carnitine Shuttle Generation Of Precursor Metabolites And Energy Carnitine Transmembrane Transport Carnitine Transport Regulation Of Energy Homeostasis Response To Peptide Hormone Positive Regulation Of Glycolytic Process Response To Peptide Fatty Acid Biosynthetic Process Regulation Of Lipid Biosynthetic Process Fatty Acid Homeostasis Cell Cycle Arrest Insulin Receptor Signaling Pathway Autophagy Quaternary Ammonium Group Transport Histone-serine Phosphorylation Oxidation-reduction Process Cellular Response To Glucose Starvation Cellular Response To Insulin Stimulus Regulation Of Glycolytic Process Regulation Of Glycogen Biosynthetic Process Negative Regulation Of TOR Signaling Regulation Of Fatty Acid Biosynthetic Process Cholesterol Biosynthetic Process Positive Regulation Of Autophagy Response To Organonitrogen Compound Regulation Of Glycogen Metabolic Process Long-chain Fatty Acid Transport Histone Phosphorylation Ammonium Transmembrane Transport Sterol Biosynthetic Process Regulation Of Lipid Metabolic Process Cellular Response To Peptide Hormone Stimulus Anion Homeostasis Response To Hormone Fatty Acid Metabolic Process Cellular Response To Peptide Regulation Of TOR Signaling Glycogen Metabolic Process Fatty Acid Transport Ammonium Transport Negative Regulation Of Cell Cycle Polysaccharide Metabolic Process Cellular Response To Organonitrogen Compound Regulation Of Fatty Acid Metabolic Process
Tagcloud ?			arms autophago biogenesis branched chop defects disposal encode epilepsy epm2b glycogen hyperphosphorylated insoluble knock lafora laforin laforinmalin lamp1 lc3 lysosomal malin myoclonus overaccumulation proteasomal s6 slight speculate starvation ubiquitinated
Tagcloud (Difference) ?			arms autophago biogenesis branched chop defects disposal encode epilepsy epm2b glycogen hyperphosphorylated insoluble knock lafora laforin laforinmalin lamp1 lc3 lysosomal malin myoclonus overaccumulation proteasomal s6 slight speculate starvation ubiquitinated
Tagcloud (Intersection) ?