NSG1 and MGST3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		NSG1	MGST3
Description		neuronal vesicle trafficking associated 1	microsomal glutathione S-transferase 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Lysosome Endosome Early Endosome Late Endosome Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Endosome Membrane Membrane Lateral Plasma Membrane Dendrite Cytoplasmic Vesicle Membrane Cytoplasmic Vesicle Early Endosome Membrane Late Endosome Membrane Golgi Cisterna Membrane Multivesicular Body Membrane Trans-Golgi Network Membrane Somatodendritic Compartment Cell Projection Lysosomal Lumen Postsynaptic Membrane Recycling Endosome Membrane Postsynaptic Endosome Glutamatergic Synapse	Nuclear Envelope Mitochondrion Mitochondrial Outer Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane
	Molecular Function	Signaling Receptor Binding Protein Binding Clathrin Light Chain Binding Ionotropic Glutamate Receptor Binding	Glutathione Transferase Activity Leukotriene-C4 Synthase Activity Glutathione Peroxidase Activity Protein Binding Oxidoreductase Activity Transferase Activity Lyase Activity Identical Protein Binding
	Biological Process	Receptor Recycling Positive Regulation Of Receptor Recycling Apoptotic Process Endosomal Transport Amyloid Precursor Protein Metabolic Process Clathrin Coat Assembly Spontaneous Synaptic Transmission Neurotransmitter Receptor Transport, Endosome To Postsynaptic Membrane Vesicle-mediated Transport In Synapse Neurotransmitter Receptor Cycle Postsynaptic Neurotransmitter Receptor Cycle Regulation Of Long-term Synaptic Potentiation	Lipid Metabolic Process Leukotriene Metabolic Process Prostanoid Metabolic Process Arachidonate Metabolic Process Leukotriene Biosynthetic Process Cellular Oxidant Detoxification
Pathways			Glutathione conjugation Aflatoxin activation and detoxification
Drugs			Glutathione
Diseases
GWAS			Metabolite levels ( 23823483) Total ventricular volume ( 21116278)
Interacting Genes		32 interacting genes: ATP6AP2 BSCL2 BTN2A1 C16orf92 CISD2 CREB3L1 CYB5R3 ERGIC3 EVI2B FCGR2A FFAR2 FNDC9 GPA33 GPR42 KASH5 KIR2DL3 MGST3 OPRM1 PDZK1IP1 PLPP2 RELL2 SLC23A2 SLC30A4 SLC7A14 SPACA1 STX12 TM4SF18 TMEM139 TMEM207 TMEM45B TMEM52B TMX2	86 interacting genes: AGPAT4 AGTRAP APOD APOL2 AQP1 AQP10 AQP3 ARL6IP1 ARL6IP6 BET1 BMP10 C11orf24 C14orf180 C3orf52 CACNG1 CCNC CDIPT CLCA4 CLRN1 CMTM5 CREB3L1 CTSA CYBC1 ERG28 F10 FAXDC2 FUNDC2 FXYD6 GIMAP1 GIMAP5 GPR152 GPX8 GRM2 HMOX2 ITGAM LEMD1 LMNA LPAR3 LRP10 MIP MRM1 MTIF3 NEU1 NINJ2 NKG7 NRM NSG1 PAGE1 PLN PLP1 PLP2 PLPP4 SCD SCN3B SEC22B SLC1A3 SLC2A5 SLC35A1 SLC39A9 SLC7A1 SMCO4 SNAP47 SNORC STX3 STX7 STX8 SYS1 TFAM TFRC TMEM107 TMEM109 TMEM120B TMEM140 TMEM229B TMEM60 TMEM86B TMX2 TSPAN12 TSPAN2 TSPAN33 UBIAD1 UNC50 VAMP3 VAMP4 YIF1A ZFPL1
Entrez ID		27065	4259
HPRD ID		09624	05192
Ensembl ID		ENSG00000168824	ENSG00000143198
Uniprot IDs		B2R5R8 P42857	O14880 Q5VV89
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Endoplasmic Reticulum Membrane	Membrane SNAP Receptor Activity SNARE Complex Endoplasmic Reticulum Membrane Protein Binding Endoplasmic Reticulum Water Channel Activity Plasma Membrane Glycerol Transmembrane Transport Organelle Fusion Water Transport Polyol Transmembrane Transport Vesicle Fusion Membrane Fusion Organelle Membrane Fusion Fluid Transport Vesicle Organization Channel Activity Endomembrane System Vesicle-mediated Transport Carbohydrate Transmembrane Transport Carbohydrate Transport Nuclear Inner Membrane Transport Vesicle Establishment Of Protein Localization To Plasma Membrane Glycerol Channel Activity Vesicle Docking One-carbon Compound Transport Acute Inflammatory Response Renal Water Absorption Urea Transmembrane Transporter Activity IgG Receptor Activity Protein Localization To Plasma Membrane Membrane Organization Regulation Of Postsynaptic Membrane Neurotransmitter Receptor Levels Chloride Channel Inhibitor Activity Renal Water Transport Antibody-dependent Cellular Cytotoxicity Fc-gamma Receptor Signaling Pathway Organelle Localization By Membrane Tethering Response To Hypoxia Golgi To Plasma Membrane Protein Transport Urea Transmembrane Transport Neurotransmitter Receptor Transport, Endosome To Postsynaptic Membrane Neurotransmitter Receptor Transport, Endosome To Plasma Membrane Response To Decreased Oxygen Levels Ventricular Cardiac Muscle Cell Development Membrane Docking Neurotransmitter Receptor Transport To Postsynaptic Membrane Protein Localization To Cell Periphery
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