NSG1 and BTN2A1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		NSG1	BTN2A1
Description		neuronal vesicle trafficking associated 1	butyrophilin subfamily 2 member A1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Lysosome Endosome Early Endosome Late Endosome Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Endosome Membrane Membrane Lateral Plasma Membrane Dendrite Cytoplasmic Vesicle Membrane Cytoplasmic Vesicle Early Endosome Membrane Late Endosome Membrane Golgi Cisterna Membrane Multivesicular Body Membrane Trans-Golgi Network Membrane Somatodendritic Compartment Cell Projection Lysosomal Lumen Postsynaptic Membrane Recycling Endosome Membrane Postsynaptic Endosome Glutamatergic Synapse	Plasma Membrane External Side Of Plasma Membrane Membrane
	Molecular Function	Signaling Receptor Binding Protein Binding Clathrin Light Chain Binding Ionotropic Glutamate Receptor Binding	Signaling Receptor Binding Protein Binding
	Biological Process	Receptor Recycling Positive Regulation Of Receptor Recycling Apoptotic Process Endosomal Transport Amyloid Precursor Protein Metabolic Process Clathrin Coat Assembly Spontaneous Synaptic Transmission Neurotransmitter Receptor Transport, Endosome To Postsynaptic Membrane Vesicle-mediated Transport In Synapse Neurotransmitter Receptor Cycle Postsynaptic Neurotransmitter Receptor Cycle Regulation Of Long-term Synaptic Potentiation	Regulation Of Cytokine Production Lipid Metabolic Process T Cell Receptor Signaling Pathway
Pathways			Butyrophilin (BTN) family interactions
Drugs
Diseases
GWAS			Autism spectrum disorder or schizophrenia ( 28540026) Brain morphology (MOSTest) ( 32665545) Chronic obstructive pulmonary disease ( 33909500) Cutaneous mastocytosis ( 32752121) Fish- and plant-related diet ( 32066663) Gastroesophageal reflux disease ( 31527586 34187846) General cognitive ability ( 29844566) Intelligence (MTAG) ( 29326435) Lung cancer ( 31577861) Lung cancer in ever smokers ( 28604730) Refractive error ( 32231278) Subcortical volume (MOSTest) ( 32665545) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		32 interacting genes: ATP6AP2 BSCL2 BTN2A1 C16orf92 CISD2 CREB3L1 CYB5R3 ERGIC3 EVI2B FCGR2A FFAR2 FNDC9 GPA33 GPR42 KASH5 KIR2DL3 MGST3 OPRM1 PDZK1IP1 PLPP2 RELL2 SLC23A2 SLC30A4 SLC7A14 SPACA1 STX12 TM4SF18 TMEM139 TMEM207 TMEM45B TMEM52B TMX2	6 interacting genes: CLDN19 CTXN3 MAL NSG1 PLPP6 STRIT1
Entrez ID		27065	11120
HPRD ID		09624	12544
Ensembl ID		ENSG00000168824	ENSG00000112763
Uniprot IDs		B2R5R8 P42857	Q7KYR7
PDB IDs			8DFW 8DFX 8DFY 8JYC 8JYE 8VC7
Enriched GO Terms of Interacting Partners?		Membrane Endoplasmic Reticulum Membrane	Schmidt-Lanterman Incisure Protein Insertion Into Plasma Membrane Hinge Region Between Urothelial Plaques Of Apical Plasma Membrane Postsynaptic Neurotransmitter Receptor Cycle Neurotransmitter Receptor Cycle Isoprenoid Diphosphate Phosphatase Activity Farnesyl Diphosphate Catabolic Process Geranylgeranyl Diphosphate Catabolic Process Spontaneous Synaptic Transmission Mesaxon Positive Regulation Of Calcium Ion Import Into Sarcoplasmic Reticulum Regulation Of Slow-twitch Skeletal Muscle Fiber Contraction Positive Regulation Of Cardiac Muscle Cell Contraction Membrane Raft Polarization Geranyl Diphosphate Metabolic Process Positive Regulation Of Neutrophil Activation Protein Localization To Paranode Region Of Axon Regulation Of Transepithelial Transport Establishment Of Protein Localization To Membrane Peptidase Activator Activity Involved In Apoptotic Process Postsynaptic Endosome Paracellular Tight Junction Channel Activity Lipid Phosphatase Activity Farnesyl Diphosphate Metabolic Process Sphingosine-1-phosphate Phosphatase Activity Regulation Of ATPase-coupled Calcium Transmembrane Transporter Activity Membrane Raft Distribution Clathrin Light Chain Binding Paracellular Transport Lysophosphatidic Acid Phosphatase Activity Membrane Raft Localization Neurotransmitter Receptor Transport, Endosome To Postsynaptic Membrane Neurotransmitter Receptor Transport, Endosome To Plasma Membrane Apical Junction Assembly Retinal Pigment Epithelium Development Paranodal Junction Protein Prenylation Protein Localization To Axon Structural Constituent Of Myelin Sheath Establishment Of Protein Localization To Postsynaptic Membrane Neurotransmitter Receptor Transport To Postsynaptic Membrane Neurotransmitter Receptor Transport To Plasma Membrane Action Potential Propagation Neuronal Action Potential Propagation Regulation Of Neutrophil Activation Membrane Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Central Nervous System Myelination Positive Regulation Of Receptor Recycling Endosome To Plasma Membrane Protein Transport
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