MGST3 and SNAP47

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MGST3	SNAP47
Description		microsomal glutathione S-transferase 3	synaptosome associated protein 47
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nuclear Envelope Mitochondrion Mitochondrial Outer Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane	Cytoplasm Plasma Membrane Endomembrane System Membrane BLOC-1 Complex SNARE Complex Synapse Perinuclear Region Of Cytoplasm Presynapse
	Molecular Function	Glutathione Transferase Activity Leukotriene-C4 Synthase Activity Glutathione Peroxidase Activity Protein Binding Oxidoreductase Activity Transferase Activity Lyase Activity Identical Protein Binding	SNAP Receptor Activity Protein Binding Syntaxin Binding
	Biological Process	Lipid Metabolic Process Leukotriene Metabolic Process Prostanoid Metabolic Process Arachidonate Metabolic Process Leukotriene Biosynthetic Process Cellular Oxidant Detoxification	Exocytosis Synaptic Vesicle Priming Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane
Pathways		Glutathione conjugation Aflatoxin activation and detoxification
Drugs		Glutathione
Diseases
GWAS		Metabolite levels ( 23823483) Total ventricular volume ( 21116278)	Height ( 28552196) Hip circumference adjusted for BMI ( 34021172) Night sleep phenotypes ( 27126917) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		86 interacting genes: AGPAT4 AGTRAP APOD APOL2 AQP1 AQP10 AQP3 ARL6IP1 ARL6IP6 BET1 BMP10 C11orf24 C14orf180 C3orf52 CACNG1 CCNC CDIPT CLCA4 CLRN1 CMTM5 CREB3L1 CTSA CYBC1 ERG28 F10 FAXDC2 FUNDC2 FXYD6 GIMAP1 GIMAP5 GPR152 GPX8 GRM2 HMOX2 ITGAM LEMD1 LMNA LPAR3 LRP10 MIP MRM1 MTIF3 NEU1 NINJ2 NKG7 NRM NSG1 PAGE1 PLN PLP1 PLP2 PLPP4 SCD SCN3B SEC22B SLC1A3 SLC2A5 SLC35A1 SLC39A9 SLC7A1 SMCO4 SNAP47 SNORC STX3 STX7 STX8 SYS1 TFAM TFRC TMEM107 TMEM109 TMEM120B TMEM140 TMEM229B TMEM60 TMEM86B TMX2 TSPAN12 TSPAN2 TSPAN33 UBIAD1 UNC50 VAMP3 VAMP4 YIF1A ZFPL1	23 interacting genes: APOC2 APOC4 AQP2 CEP57L1 F11R FAM9B FATE1 GOLGA2 KASH5 KLC3 LIME1 LRRC4C MAGEA6 MGST3 MID2 PVR RNF170 SAR1A SPAG5 STX1A STX1B STX4 TRIM59
Entrez ID		4259	116841
HPRD ID		05192	17148
Ensembl ID		ENSG00000143198	ENSG00000143740
Uniprot IDs		O14880 Q5VV89	A0A087X0B7 Q5SQN1
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane SNAP Receptor Activity SNARE Complex Endoplasmic Reticulum Membrane Protein Binding Endoplasmic Reticulum Water Channel Activity Plasma Membrane Glycerol Transmembrane Transport Organelle Fusion Water Transport Polyol Transmembrane Transport Vesicle Fusion Membrane Fusion Organelle Membrane Fusion Fluid Transport Vesicle Organization Channel Activity Endomembrane System Vesicle-mediated Transport Carbohydrate Transmembrane Transport Carbohydrate Transport Nuclear Inner Membrane Transport Vesicle Establishment Of Protein Localization To Plasma Membrane Glycerol Channel Activity Vesicle Docking One-carbon Compound Transport Acute Inflammatory Response Renal Water Absorption Urea Transmembrane Transporter Activity IgG Receptor Activity Protein Localization To Plasma Membrane Membrane Organization Regulation Of Postsynaptic Membrane Neurotransmitter Receptor Levels Chloride Channel Inhibitor Activity Renal Water Transport Antibody-dependent Cellular Cytotoxicity Fc-gamma Receptor Signaling Pathway Organelle Localization By Membrane Tethering Response To Hypoxia Golgi To Plasma Membrane Protein Transport Urea Transmembrane Transport Neurotransmitter Receptor Transport, Endosome To Postsynaptic Membrane Neurotransmitter Receptor Transport, Endosome To Plasma Membrane Response To Decreased Oxygen Levels Ventricular Cardiac Muscle Cell Development Membrane Docking Neurotransmitter Receptor Transport To Postsynaptic Membrane Protein Localization To Cell Periphery	Microtubule Binding SNAP Receptor Activity SNARE Complex Microtubule Synaptic Vesicle Docking Regulation Of Synaptic Vesicle Priming SNARE Complex Assembly SNARE Binding Vesicle Docking Ciliary Rootlet Organelle Localization By Membrane Tethering Very-low-density Lipoprotein Particle Positive Regulation Of Neurotransmitter Secretion Organelle Localization Schaffer Collateral - CA1 Synapse Membrane Docking Neurotransmitter Transport Vesicle Fusion Organelle Membrane Fusion High-density Lipoprotein Particle Host-mediated Suppression Of Symbiont Invasion Presynaptic Active Zone Membrane Organelle Fusion Vesicle Organization Positive Regulation Of Excitatory Postsynaptic Potential Calcium-ion Regulated Exocytosis Positive Regulation Of Synaptic Transmission Synaptic Vesicle Exocytosis Acylglycerol Homeostasis Triglyceride Homeostasis Spindle Organization Vesicle Docking Involved In Exocytosis Myosin Head/neck Binding Membrane Fusion Sphingomyelin Phosphodiesterase Activator Activity Positive Regulation Of Spontaneous Neurotransmitter Secretion Negative Regulation Of Macropinocytosis Negative Regulation Of Synaptic Vesicle Recycling Identical Protein Binding Intracellular Protein Localization Positive Regulation Of Regulated Secretory Pathway Modulation Of Excitatory Postsynaptic Potential Protein Localization To Cytoskeleton Germ Cell Development Positive Regulation Of Very-low-density Lipoprotein Particle Remodeling Lumenal Side Of Membrane Glycerol Transmembrane Transporter Activity Susceptibility To T Cell Mediated Cytotoxicity Exocytosis Positive Regulation Of Eosinophil Degranulation
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