NSG1 and SPACA1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		NSG1	SPACA1
Description		neuronal vesicle trafficking associated 1	sperm acrosome associated 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Lysosome Endosome Early Endosome Late Endosome Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Endosome Membrane Membrane Lateral Plasma Membrane Dendrite Cytoplasmic Vesicle Membrane Cytoplasmic Vesicle Early Endosome Membrane Late Endosome Membrane Golgi Cisterna Membrane Multivesicular Body Membrane Trans-Golgi Network Membrane Somatodendritic Compartment Cell Projection Lysosomal Lumen Postsynaptic Membrane Recycling Endosome Membrane Postsynaptic Endosome Glutamatergic Synapse	Acrosomal Vesicle Inner Acrosomal Membrane Acrosomal Membrane Membrane Cytoplasmic Vesicle
	Molecular Function	Signaling Receptor Binding Protein Binding Clathrin Light Chain Binding Ionotropic Glutamate Receptor Binding	Protein Binding
	Biological Process	Receptor Recycling Positive Regulation Of Receptor Recycling Apoptotic Process Endosomal Transport Amyloid Precursor Protein Metabolic Process Clathrin Coat Assembly Spontaneous Synaptic Transmission Neurotransmitter Receptor Transport, Endosome To Postsynaptic Membrane Vesicle-mediated Transport In Synapse Neurotransmitter Receptor Cycle Postsynaptic Neurotransmitter Receptor Cycle Regulation Of Long-term Synaptic Potentiation	Acrosome Assembly Spermatogenesis
Pathways
Drugs
Diseases
GWAS			Echocardiographic traits ( 17903301) Left superior temporal gyrus thickness (schizophrenia interaction) ( 26249676) Triglyceride levels x SSRI levels (escitalopram or citalopram) interaction in schizophrenia or bipolar disorder ( 33824429)
Interacting Genes		32 interacting genes: ATP6AP2 BSCL2 BTN2A1 C16orf92 CISD2 CREB3L1 CYB5R3 ERGIC3 EVI2B FCGR2A FFAR2 FNDC9 GPA33 GPR42 KASH5 KIR2DL3 MGST3 OPRM1 PDZK1IP1 PLPP2 RELL2 SLC23A2 SLC30A4 SLC7A14 SPACA1 STX12 TM4SF18 TMEM139 TMEM207 TMEM45B TMEM52B TMX2	25 interacting genes: AGPAT4 ATP6V0B ATP6V0C BNIP3 CACNG7 CD72 CLDN19 CTXN3 EMP1 EMP3 GIMAP5 LSMEM2 NRSN1 NSG1 PLN PMP22 RPRM SERP2 SERTM1 SGCG SMAGP SMIM3 THSD7B TMEM140 TMEM47
Entrez ID		27065	81833
HPRD ID		09624	15419
Ensembl ID		ENSG00000168824	ENSG00000118434
Uniprot IDs		B2R5R8 P42857	Q9HBV2
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Endoplasmic Reticulum Membrane	Membrane Bleb Assembly Proton-transporting Two-sector ATPase Complex, Proton-transporting Domain Golgi Lumen Acidification Vacuolar Proton-transporting V-type ATPase, V0 Domain Proton-transporting V-type ATPase, V0 Domain Endosomal Lumen Acidification Proton-transporting V-type ATPase Complex Proton Transmembrane Transporter Activity Proton-transporting ATPase Activity, Rotational Mechanism Lysosomal Lumen Acidification Endosome Membrane Multivesicular Body Membrane Clathrin-coated Vesicle Membrane Regulation Of Lysosomal Lumen PH Vacuolar Acidification Mitochondrion Autophagosome Adaptor Activity Circadian Sleep/wake Cycle, Sleep Phospholamban Complex Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway Involved In Heart Process Protein Localization To Postsynapse Protein Localization To Postsynaptic Membrane Postsynaptic Neurotransmitter Receptor Cycle Neurotransmitter Receptor Cycle
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