MGST3 and UNC50

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MGST3	UNC50
Description		microsomal glutathione S-transferase 3	unc-50 inner nuclear membrane RNA binding protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nuclear Envelope Mitochondrion Mitochondrial Outer Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane	Golgi Membrane Nucleus Nuclear Inner Membrane Golgi Apparatus Membrane
	Molecular Function	Glutathione Transferase Activity Leukotriene-C4 Synthase Activity Glutathione Peroxidase Activity Protein Binding Oxidoreductase Activity Transferase Activity Lyase Activity Identical Protein Binding	RNA Binding Protein Binding
	Biological Process	Lipid Metabolic Process Leukotriene Metabolic Process Prostanoid Metabolic Process Arachidonate Metabolic Process Leukotriene Biosynthetic Process Cellular Oxidant Detoxification	Protein Localization To Cell Surface
Pathways		Glutathione conjugation Aflatoxin activation and detoxification
Drugs		Glutathione
Diseases
GWAS		Metabolite levels ( 23823483) Total ventricular volume ( 21116278)	Diverticular disease ( 30177863)
Interacting Genes		86 interacting genes: AGPAT4 AGTRAP APOD APOL2 AQP1 AQP10 AQP3 ARL6IP1 ARL6IP6 BET1 BMP10 C11orf24 C14orf180 C3orf52 CACNG1 CCNC CDIPT CLCA4 CLRN1 CMTM5 CREB3L1 CTSA CYBC1 ERG28 F10 FAXDC2 FUNDC2 FXYD6 GIMAP1 GIMAP5 GPR152 GPX8 GRM2 HMOX2 ITGAM LEMD1 LMNA LPAR3 LRP10 MIP MRM1 MTIF3 NEU1 NINJ2 NKG7 NRM NSG1 PAGE1 PLN PLP1 PLP2 PLPP4 SCD SCN3B SEC22B SLC1A3 SLC2A5 SLC35A1 SLC39A9 SLC7A1 SMCO4 SNAP47 SNORC STX3 STX7 STX8 SYS1 TFAM TFRC TMEM107 TMEM109 TMEM120B TMEM140 TMEM229B TMEM60 TMEM86B TMX2 TSPAN12 TSPAN2 TSPAN33 UBIAD1 UNC50 VAMP3 VAMP4 YIF1A ZFPL1	35 interacting genes: AQP6 CLEC10A CLRN1 CREB3 CYB5R3 DARS2 EBP ELOVL4 ERGIC3 FAM209A FCER1G FFAR2 FITM2 GPR152 GPX8 HSD17B11 HSD17B13 IFNGR2 KCNJ6 LMNA MFF MGST3 MTIF3 MUC1 REEP4 SAR1A SGPL1 SLC10A1 SLC10A6 SLC71A2 TIMMDC1 TMED8 TMEM14B TMEM167B TMEM234
Entrez ID		4259	25972
HPRD ID		05192	18259
Ensembl ID		ENSG00000143198	ENSG00000115446
Uniprot IDs		O14880 Q5VV89	A0A0S2Z612 J3KQ47 Q53HI1
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane SNAP Receptor Activity SNARE Complex Endoplasmic Reticulum Membrane Protein Binding Endoplasmic Reticulum Water Channel Activity Plasma Membrane Glycerol Transmembrane Transport Organelle Fusion Water Transport Polyol Transmembrane Transport Vesicle Fusion Membrane Fusion Organelle Membrane Fusion Fluid Transport Vesicle Organization Channel Activity Endomembrane System Vesicle-mediated Transport Carbohydrate Transmembrane Transport Carbohydrate Transport Nuclear Inner Membrane Transport Vesicle Establishment Of Protein Localization To Plasma Membrane Glycerol Channel Activity Vesicle Docking One-carbon Compound Transport Acute Inflammatory Response Renal Water Absorption Urea Transmembrane Transporter Activity IgG Receptor Activity Protein Localization To Plasma Membrane Membrane Organization Regulation Of Postsynaptic Membrane Neurotransmitter Receptor Levels Chloride Channel Inhibitor Activity Renal Water Transport Antibody-dependent Cellular Cytotoxicity Fc-gamma Receptor Signaling Pathway Organelle Localization By Membrane Tethering Response To Hypoxia Golgi To Plasma Membrane Protein Transport Urea Transmembrane Transport Neurotransmitter Receptor Transport, Endosome To Postsynaptic Membrane Neurotransmitter Receptor Transport, Endosome To Plasma Membrane Response To Decreased Oxygen Levels Ventricular Cardiac Muscle Cell Development Membrane Docking Neurotransmitter Receptor Transport To Postsynaptic Membrane Protein Localization To Cell Periphery	Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum Steroid Dehydrogenase Activity Mitochondrial Membrane Bile Acid:sodium Symporter Activity Protein Binding
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