MGST3 and AQP10

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MGST3	AQP10
Description		microsomal glutathione S-transferase 3	aquaporin 10
Image		No pdb structure
GO Annotations	Cellular Component	Nuclear Envelope Mitochondrion Mitochondrial Outer Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane	Lipid Droplet Plasma Membrane Membrane Basolateral Plasma Membrane Apical Plasma Membrane
	Molecular Function	Glutathione Transferase Activity Leukotriene-C4 Synthase Activity Glutathione Peroxidase Activity Protein Binding Oxidoreductase Activity Transferase Activity Lyase Activity Identical Protein Binding	Protein Binding Urea Transmembrane Transporter Activity Water Channel Activity Glycerol Channel Activity Channel Activity
	Biological Process	Lipid Metabolic Process Leukotriene Metabolic Process Prostanoid Metabolic Process Arachidonate Metabolic Process Leukotriene Biosynthetic Process Cellular Oxidant Detoxification	Water Transport Response To Toxic Substance Glycerol Transmembrane Transport Protein Homotetramerization Transmembrane Transport Urea Transmembrane Transport
Pathways		Glutathione conjugation Aflatoxin activation and detoxification	Passive transport by Aquaporins
Drugs		Glutathione
Diseases
GWAS		Metabolite levels ( 23823483) Total ventricular volume ( 21116278)	Bipolar disorder ( 31043756) Mean corpuscular hemoglobin ( 27863252 32888494) Mean corpuscular volume ( 27863252 32888494) Non-albumin protein levels ( 29403010) Parkinson's disease progression (motor) ( 33111402) Red cell distribution width ( 32888494) Serum total protein levels ( 29403010)
Interacting Genes		86 interacting genes: AGPAT4 AGTRAP APOD APOL2 AQP1 AQP10 AQP3 ARL6IP1 ARL6IP6 BET1 BMP10 C11orf24 C14orf180 C3orf52 CACNG1 CCNC CDIPT CLCA4 CLRN1 CMTM5 CREB3L1 CTSA CYBC1 ERG28 F10 FAXDC2 FUNDC2 FXYD6 GIMAP1 GIMAP5 GPR152 GPX8 GRM2 HMOX2 ITGAM LEMD1 LMNA LPAR3 LRP10 MIP MRM1 MTIF3 NEU1 NINJ2 NKG7 NRM NSG1 PAGE1 PLN PLP1 PLP2 PLPP4 SCD SCN3B SEC22B SLC1A3 SLC2A5 SLC35A1 SLC39A9 SLC7A1 SMCO4 SNAP47 SNORC STX3 STX7 STX8 SYS1 TFAM TFRC TMEM107 TMEM109 TMEM120B TMEM140 TMEM229B TMEM60 TMEM86B TMX2 TSPAN12 TSPAN2 TSPAN33 UBIAD1 UNC50 VAMP3 VAMP4 YIF1A ZFPL1	20 interacting genes: ARL13B CISD2 CREB3L1 CYBC1 ERGIC3 GPR152 GPR37L1 KIR2DL3 LMNA LYVE1 MGST3 NEMP1 PGRMC2 PLP1 PVR SAR1A SCN3B SSMEM1 SYT2 TMEM167B
Entrez ID		4259	89872
HPRD ID		05192	07361
Ensembl ID		ENSG00000143198	ENSG00000143595
Uniprot IDs		O14880 Q5VV89	Q96PS8
PDB IDs			6F7H
Enriched GO Terms of Interacting Partners?		Membrane SNAP Receptor Activity SNARE Complex Endoplasmic Reticulum Membrane Protein Binding Endoplasmic Reticulum Water Channel Activity Plasma Membrane Glycerol Transmembrane Transport Organelle Fusion Water Transport Polyol Transmembrane Transport Vesicle Fusion Membrane Fusion Organelle Membrane Fusion Fluid Transport Vesicle Organization Channel Activity Endomembrane System Vesicle-mediated Transport Carbohydrate Transmembrane Transport Carbohydrate Transport Nuclear Inner Membrane Transport Vesicle Establishment Of Protein Localization To Plasma Membrane Glycerol Channel Activity Vesicle Docking One-carbon Compound Transport Acute Inflammatory Response Renal Water Absorption Urea Transmembrane Transporter Activity IgG Receptor Activity Protein Localization To Plasma Membrane Membrane Organization Regulation Of Postsynaptic Membrane Neurotransmitter Receptor Levels Chloride Channel Inhibitor Activity Renal Water Transport Antibody-dependent Cellular Cytotoxicity Fc-gamma Receptor Signaling Pathway Organelle Localization By Membrane Tethering Response To Hypoxia Golgi To Plasma Membrane Protein Transport Urea Transmembrane Transport Neurotransmitter Receptor Transport, Endosome To Postsynaptic Membrane Neurotransmitter Receptor Transport, Endosome To Plasma Membrane Response To Decreased Oxygen Levels Ventricular Cardiac Muscle Cell Development Membrane Docking Neurotransmitter Receptor Transport To Postsynaptic Membrane Protein Localization To Cell Periphery	Membrane Nuclear Envelope
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