MGST3

Gene Name		microsomal glutathione S-transferase 3
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nuclear Envelope Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle Extracellular Vesicular Exosome
	Molecular Function	Glutathione Transferase Activity Peroxidase Activity Glutathione Peroxidase Activity
	Biological Process	Lipid Metabolic Process Xenobiotic Metabolic Process Signal Transduction Small Molecule Metabolic Process Oxidation-reduction Process Glutathione Derivative Biosynthetic Process
Pathways		Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD) Defective AHCY causes Hypermethioninemia with S-adenosylhomocysteine hydrolase deficiency (HMAHCHD) Defective TPMT causes Thiopurine S-methyltransferase deficiency (TPMT deficiency) Defective MAT1A causes Methionine adenosyltransferase deficiency (MATD) Aflatoxin activation and detoxification Defective UGT1A4 causes hyperbilirubinemia Glutathione conjugation Metabolic disorders of biological oxidation enzymes Phase II conjugation Defective UGT1A1 causes hyperbilirubinemia Defective SLC35D1 causes Schneckenbecken dysplasia (SCHBCKD) Biological oxidations Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD) Defective GGT1 causes Glutathionuria (GLUTH) Defective ACY1 causes encephalopathy Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)
Drugs
Diseases
GWAS		Total ventricular volume ( 21116278)
Protein-protein Interactions		2 interactors: CCNC F10
Entrez ID		4259
HPRD ID		05192
Ensembl ID		ENSG00000143198
Uniprot IDs		O14880 Q5VV89
PDB IDs
Enriched GO Terms of Interacting Partners?		Blood Coagulation, Extrinsic Pathway Peptidyl-glutamic Acid Carboxylation Blood Coagulation, Intrinsic Pathway
Tagcloud ?		ankrd1 ccl13 ccl3l3 ccl7 ccl9 csda dbq1 egr3 gadd45g gstm2 herpud1 hsp90aa hspa1a hspd1 hsph1 mybpc3 myh7 myom2 nfkbid nppa opioidergic ptgds saa1 sarcomeric selp serpina3 serpinh1 slp xirp1