GJA3 and MIP

Number of citations of the paper that reports this interaction (PMID 9664032)
7

Data Source:
HPRD (in vivo)

		GJA3	MIP
Gene Name		gap junction protein, alpha 3, 46kDa	major intrinsic protein of lens fiber
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Connexon Complex Integral Component Of Membrane	Plasma Membrane Integral Component Of Plasma Membrane Gap Junction Apical Plasma Membrane Intracellular Membrane-bounded Organelle Intracellular Canaliculus
	Molecular Function	Gap Junction Channel Activity	Structural Constituent Of Eye Lens Transporter Activity Calmodulin Binding Water Channel Activity Glycerol Channel Activity
	Biological Process	Transport Cell-cell Signaling Visual Perception Transmembrane Transport	Lens Development In Camera-type Eye Water Transport Visual Perception Cellular Water Homeostasis Canalicular Bile Acid Transport Glycerol Transport Ion Transmembrane Transport Response To Stimulus Transmembrane Transport
Pathways		Gap junction assembly Gap junction trafficking and regulation Gap junction trafficking	Passive transport by Aquaporins Aquaporin-mediated transport
Drugs
Diseases
GWAS
Protein-Protein Interactions		5 interactors: CAV1 GJA1 MIP PRKCG TJP1	9 interactors: CALM1 CRYAA CRYAB CRYBB2 CRYGC FOXA2 GJA3 GJA8 PRKACA
Entrez ID		2700	4284
HPRD ID		00415	01098
Ensembl ID		ENSG00000121743	ENSG00000135517
Uniprot IDs		Q9Y6H8	P30301
PDB IDs
Enriched GO Terms of Interacting Partners?		Cellular Chemical Homeostasis Cellular Homeostasis Regulation Of Membrane Repolarization Chemical Homeostasis Positive Regulation Of Vasoconstriction Negative Regulation Of Endothelial Cell Proliferation Blood Circulation Regulation Of Cardiac Muscle Cell Contraction Homeostatic Process Regulation Of Vasoconstriction Regulation Of Cardiac Muscle Contraction Regulation Of Endothelial Cell Proliferation Regulation Of Striated Muscle Contraction Regulation Of Body Fluid Levels Endothelium Development Wound Healing Lens Development In Camera-type Eye Negative Regulation Of Protein Ubiquitination Cell-cell Signaling Involved In Cell-cell Junction Organization Regulation Of Membrane Repolarization During Action Potential Positive Regulation Of Mismatch Repair Negative Regulation Of Peptidyl-tyrosine Autophosphorylation Milk Ejection Vascular Transport Tissue Remodeling Response To Wounding Cell-cell Junction Assembly Negative Regulation Of Epithelial Cell Proliferation Regulation Of Wound Healing Response To Glucose Multicellular Organismal Development Anatomical Structure Development Regulation Of Mismatch Repair Positive Regulation Of Cell Communication By Chemical Coupling Nitric Oxide Homeostasis Atrial Ventricular Junction Remodeling Regulation Of Muscle Contraction Membrane Organization Regulation Of Ion Homeostasis Regulation Of Heart Contraction Cell-cell Signaling Cytosolic Calcium Ion Homeostasis Response To Organic Substance Receptor Internalization Involved In Canonical Wnt Signaling Pathway Regulation Of Cardiac Muscle Cell Action Potential Involved In Regulation Of Contraction Regulation Of Inward Rectifier Potassium Channel Activity Response To Carbohydrate Regulation Of Calcium Ion Transport Apoptotic Process Developmental Process	Visual Perception Sensory Perception Of Light Stimulus Sensory Perception Camera-type Eye Development Negative Regulation Of Transport Eye Development Regulation Of Intracellular Transport Organ Development Cellular Response To Radiation Regulation Of Cellular Localization Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Neurological System Process Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Regulation Of Rhodopsin Mediated Signaling Pathway Sensory Organ Development Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Activation Of Adenylate Cyclase Activity Rhodopsin Mediated Signaling Pathway Positive Regulation Of Adenylate Cyclase Activity Protein Homooligomerization Positive Regulation Of Lyase Activity System Development Activation Of Phospholipase C Activity Regulation Of Adenylate Cyclase Activity Positive Regulation Of Phospholipase C Activity Regulation Of Calcium Ion Transmembrane Transport Regulation Of Calcium Ion Transmembrane Transporter Activity Positive Regulation Of CAMP Biosynthetic Process Cell-cell Signaling Regulation Of Cyclase Activity Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Positive Regulation Of CAMP Metabolic Process Multicellular Organismal Development Positive Regulation Of Phospholipase Activity Regulation Of Heart Rate Negative Regulation Of Phosphorylation Regulation Of Cardiac Muscle Contraction Regulation Of Cation Channel Activity Phototransduction, Visible Light Anatomical Structure Development Negative Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Positive Regulation Of Dense Core Granule Biogenesis Negative Regulation Of Detection Of Glucose Regulation Of Calcium Ion Transport Into Cytosol Positive Regulation Of Cyclic Nucleotide Metabolic Process Regulation Of Phospholipase Activity Protein Oligomerization Regulation Of Striated Muscle Contraction Regulation Of CAMP Biosynthetic Process
Tagcloud ?		aiims beaded bfsp1 cataract congenital cryaa cryab cryba1 cryba4 crybb1 crybb2 crybb3 crygs crystallin cx d85n delhi e155k e75k expands filament fourteen gja8 m1v ophthalmic sciences studio transparency y67n	7b11 aminoxypentane augmented broadening ccr1 ccr2 ccr3 ccr5 chemokine chemokines chemotactic cxc cxcr1 eotaxin hcc2 leukocytes mcp migrate migrated monocyte orienting pmn polymorphonuclear prototypic rantes reorients speculate th1 th2
Tagcloud (Difference) ?		aiims beaded bfsp1 cataract congenital cryaa cryab cryba1 cryba4 crybb1 crybb2 crybb3 crygs crystallin cx d85n delhi e155k e75k expands filament fourteen gja8 m1v ophthalmic sciences studio transparency y67n	7b11 aminoxypentane augmented broadening ccr1 ccr2 ccr3 ccr5 chemokine chemokines chemotactic cxc cxcr1 eotaxin hcc2 leukocytes mcp migrate migrated monocyte orienting pmn polymorphonuclear prototypic rantes reorients speculate th1 th2
Tagcloud (Intersection) ?