MIP and GOLM1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MIP	GOLM1
Description		major intrinsic protein of lens fiber	golgi membrane protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Apical Plasma Membrane Anchoring Junction	Extracellular Space Endoplasmic Reticulum Lumen Golgi Apparatus Plasma Membrane Membrane
	Molecular Function	Structural Constituent Of Eye Lens Protein Binding Calmodulin Binding Water Channel Activity Channel Activity Cell Adhesion Mediator Activity	Protein Binding
	Biological Process	Lens Development In Camera-type Eye Water Transport Visual Perception Homotypic Cell-cell Adhesion Maintenance Of Lens Transparency Transmembrane Transport Gap Junction-mediated Intercellular Transport	Nucleus Organization Regulation Of Lipid Metabolic Process
Pathways		Passive transport by Aquaporins	Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation
Drugs		B-nonylglucoside
Diseases
GWAS		Axial length ( 24144296) Lipoprotein (a) levels ( 33730874) Serum metabolite levels ( 33031748)	Blood protein levels ( 30072576) Logical memory (delayed recall) in normal cognition ( 29274321)
Interacting Genes		48 interacting genes: AQP6 AQP9 ATP6V0B CALM1 CD40 CISD2 CLDN5 CRYAA CRYAB CRYBB2 CRYGC ERGIC3 ERVFRD-1 FAM209A FCGR2A FOXA2 GJA3 GJA8 GJB5 GOLM1 GPX8 KCNJ6 LHFPL5 LMNA LRRC4C MFF MGST3 MRM3 MRPS18B MUC1 PDZK1IP1 PRKACA RELL2 SAR1A SGPL1 SLC14A1 SLC18A1 SSMEM1 STX1A STX2 SYAP1 SYT1 SYT2 TMEM139 TMEM154 TMEM52B TMX2 ZFPL1	76 interacting genes: ABI3 AIG1 ANKRD46 ASPH B3GNT4 BCL2L1 C1orf174 C1QL4 CDIPT CIAO1 CLDN4 CLDND2 CLK1 CNPY3 DCK DCTN2 DESI1 DEXI EFTUD2 EIF2B3 EIF3J ELAC2 FLOT1 FTH1 FUT9 GALNT15 GAST GEMIN7 GET3 GLB1 GRIK5 GUCA2A HGFAC HMGB1 HSD17B13 IGFBP5 INSIG2 JAGN1 KCNE3 LAT LSM12 MED22 MIP NDUFV2 NEU1 NINJ1 NIPSNAP3A NRSN2 PGRMC1 RACK1 RIPPLY2 RPA2 RPL13A SFTPC SLC13A5 SLC30A3 SLC40A1 SLC5A4 SLCO3A1 ST6GAL2 STRIT1 SYT1 TF THSD7A TMEM109 TMEM140 TMEM147 TMEM176A TMEM86B TMEM98 TMPO TMUB1 TMUB2 TSG101 VSTM1 ZFAND3
Entrez ID		4284	51280
HPRD ID		01098	08428
Ensembl ID		ENSG00000135517	ENSG00000135052
Uniprot IDs		P30301	B3KNK9 Q8NBJ4
PDB IDs			8YBC
Enriched GO Terms of Interacting Partners?		Membrane Lens Development In Camera-type Eye Structural Constituent Of Eye Lens Structural Molecule Activity Urea Channel Activity Gap Junction Channel Activity Connexin Complex SNARE Binding Synaptic Vesicle Membrane One-carbon Compound Transport Water Transport Gap Junction Calcium-dependent Protein Binding Organelle Localization By Membrane Tethering Clathrin-sculpted Monoamine Transport Vesicle Membrane Urea Transmembrane Transporter Activity Membrane Docking Camera-type Eye Development Gap Junction-mediated Intercellular Transport Fluid Transport Plasma Membrane Protein Binding Regulation Of Calcium Ion-dependent Exocytosis Chromaffin Granule Membrane Urea Transmembrane Transport Tubulin Complex Assembly Intercellular Transport Amine Transport Urea Transport Modulation Of Chemical Synaptic Transmission Eye Development Positive Regulation Of Catecholamine Secretion Calcium-dependent Activation Of Synaptic Vesicle Fusion Water Channel Activity Calcium Channel Inhibitor Activity Vesicle Docking Detection Of Calcium Ion Positive Regulation Of Calcium Ion-dependent Exocytosis Dense Core Granule Calcium Ion Sensor Activity Voltage-gated Potassium Channel Complex Sensory Organ Development Positive Regulation Of Neurotransmitter Secretion Positive Regulation Of Dendrite Extension Positive Regulation Of Vesicle Fusion Glutathione Peroxidase Activity	Membrane
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