AMPD1 and MYH2

Number of citations of the paper that reports this interaction (PMID 9730972)
1

Data Source:
HPRD (in vivo)

		AMPD1	MYH2
Gene Name		adenosine monophosphate deaminase 1	myosin, heavy chain 2, skeletal muscle, adult
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol	Golgi Apparatus Actomyosin Contractile Ring Cytosol Muscle Myosin Complex Cell-cell Junction Myofibril Sarcomere A Band Myosin Filament Protein Complex
	Molecular Function	AMP Deaminase Activity Myosin Heavy Chain Binding Metal Ion Binding	Microfilament Motor Activity Actin Binding Protein Binding Calmodulin Binding ATP Binding
	Biological Process	Purine Nucleobase Metabolic Process Response To Organic Substance IMP Salvage Purine-containing Compound Salvage Small Molecule Metabolic Process Nucleobase-containing Small Molecule Metabolic Process	Plasma Membrane Repair Muscle Contraction Metabolic Process Response To Activity Muscle Filament Sliding Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Innate Immune Response Membrane Organization
Pathways		Purine metabolism Metabolism of nucleotides Purine salvage	Translocation of GLUT4 to the plasma membrane Fcgamma receptor (FCGR) dependent phagocytosis Regulation of actin dynamics for phagocytic cup formation Innate Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		1 interactors: MYH2	6 interactors: AMPD1 DGKD OBSCN PRKCE PTK2B S100A4
Entrez ID		270	4620
HPRD ID		00040	01173
Ensembl ID		ENSG00000116748	ENSG00000125414
Uniprot IDs		P23109	Q567P6 Q9UKX2
PDB IDs
Enriched GO Terms of Interacting Partners?		Plasma Membrane Repair Muscle Filament Sliding Actin-myosin Filament Sliding Actin-mediated Cell Contraction Response To Activity Actin Filament-based Movement Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Muscle Contraction Plasma Membrane Organization Phagocytosis Muscle System Process Fc Receptor Signaling Pathway Immune Response-activating Cell Surface Receptor Signaling Pathway	Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Response To Organic Substance Phosphate-containing Compound Metabolic Process Positive Regulation Of Epithelial Cell Migration Response To Ammonium Ion Negative Regulation Of Ion Transport Positive Regulation Of Cellular Glucuronidation Positive Regulation Of Actin Filament Polymerization Positive Regulation Of Synaptic Transmission Actomyosin Structure Organization Regulation Of Receptor Activity Positive Regulation Of Cell-substrate Adhesion Positive Regulation Of Protein Polymerization Regulation Of Intracellular Signal Transduction Cell Activation Regulation Of CGMP-mediated Signaling Marginal Zone B Cell Differentiation Positive Regulation Of B Cell Chemotaxis TRAM-dependent Toll-like Receptor 4 Signaling Pathway Phosphorylation Response To Ethanol Intracellular Signal Transduction Regulation Of Ion Transmembrane Transporter Activity Regulation Of Epithelial Cell Migration Response To Alkaloid Regulation Of Transmembrane Transporter Activity Regulation Of Carbohydrate Metabolic Process Leukocyte Activation Involved In Immune Response Positive Regulation Of Cytosolic Calcium Ion Concentration Regulation Of Ion Homeostasis Positive Regulation Of Intracellular Signal Transduction Protein Localization To M-band Positive Regulation Of Protein Complex Assembly Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Regulation Of Actin Filament Polymerization Cytosolic Calcium Ion Homeostasis Activation Of Janus Kinase Activity Platelet Activation Regulation Of Cell-substrate Adhesion Positive Regulation Of Cytoskeleton Organization Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Regulation Of Peptidyl-tyrosine Phosphorylation Neurotrophin TRK Receptor Signaling Pathway Apoptotic Process Neurotrophin Signaling Pathway Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Tagcloud ?		adenosine allele altering athletic c34t caa cc champions codon converts ct deaminase elite exon isoform monophosphate nonsense olympic polish premature rowers stop stronger taa tt unrelated volunteers whole	breakpoint breaks coliai cryb1 d17s1 d17s19 d17s6 d17z erba1 gaa galk gcsf ghc hox2 hybrids isoenzymes mpo myh1 ngfr ngl probes pter qter regionally rnp2 rnu2 tk1 transfectant um
Tagcloud (Difference) ?		adenosine allele altering athletic c34t caa cc champions codon converts ct deaminase elite exon isoform monophosphate nonsense olympic polish premature rowers stop stronger taa tt unrelated volunteers whole	breakpoint breaks coliai cryb1 d17s1 d17s19 d17s6 d17z erba1 gaa galk gcsf ghc hox2 hybrids isoenzymes mpo myh1 ngfr ngl probes pter qter regionally rnp2 rnu2 tk1 transfectant um
Tagcloud (Intersection) ?