LATS2 and MOB3C

Number of citations of the paper that reports this interaction (PMID 19739119)
11

Data Source:
BioGRID (pull down)

		LATS2	MOB3C
Gene Name		large tumor suppressor kinase 2	MOB kinase activator 3C
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Spindle Pole Nucleus Cytoplasm Microtubule Organizing Center Cytosol
	Molecular Function	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Metal Ion Binding	Metal Ion Binding
	Biological Process	G1/S Transition Of Mitotic Cell Cycle Protein Phosphorylation Mitotic Nuclear Division Hormone-mediated Signaling Pathway Keratinocyte Differentiation Cellular Protein Localization Hippo Signaling Intracellular Signal Transduction Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Regulation Of Organ Growth Cell Division Negative Regulation Of Canonical Wnt Signaling Pathway
Pathways		Signaling by Hippo
Drugs
Diseases
GWAS
Protein-Protein Interactions		19 interactors: ABL1 AJUBA AMOT AURKB CDK2 CDKN1A CHEK1 CHEK2 CTNNB1 DYRK1A MOB3A MOB3B MOB3C MOB4 SNAI1 STK3 TAZ YAP1 YWHAG	12 interactors: APP CMTM3 FAM118A KRT40 LATS1 LATS2 NT5C2 SIAH1 TDO2 TFCP2 TNIP1 ZBTB10
Entrez ID		26524	148932
HPRD ID		07277	17584
Ensembl ID		ENSG00000150457	ENSG00000142961
Uniprot IDs		Q9NRM7	Q70IA8
PDB IDs
Enriched GO Terms of Interacting Partners?		G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Cell Cycle Hippo Signaling Regulation Of Cellular Component Organization Positive Regulation Of Cellular Metabolic Process Mitotic Cell Cycle Process Negative Regulation Of Mitotic Cell Cycle Cell Cycle Process Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Cell Cycle Mitotic Cell Cycle Phase Transition Regulation Of Protein Metabolic Process Cell Cycle Phase Transition DNA Damage Induced Protein Phosphorylation Positive Regulation Of Stem Cell Differentiation Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Metabolic Process Developmental Process Intrinsic Apoptotic Signaling Pathway Regulation Of Signal Transduction Regulation Of Nephron Tubule Epithelial Cell Differentiation Negative Regulation Of Signal Transduction Regulation Of Mitotic Cell Cycle Regulation Of Epithelial Cell Differentiation Involved In Kidney Development Protein Autophosphorylation Cell Cycle Checkpoint Negative Regulation Of Signaling Negative Regulation Of Kinase Activity Regulation Of Metabolic Process Regulation Of Gene Expression Signal Transduction In Response To DNA Damage Regulation Of Nitrogen Compound Metabolic Process Regulation Of Signaling Regulation Of Cell Cycle Process Protein Phosphorylation Phosphorylation Intracellular Signal Transduction Negative Regulation Of Biosynthetic Process Regulation Of Cell Cycle Negative Regulation Of Transferase Activity Regulation Of Wnt Signaling Pathway Regulation Of Response To DNA Damage Stimulus Histone Phosphorylation Positive Regulation Of Epithelial To Mesenchymal Transition Regulation Of RNA Metabolic Process Regulation Of Apoptotic Process Regulation Of Cell Proliferation Cellular Response To Radiation Apoptotic Signaling Pathway	Hippo Signaling Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Neuron Apoptotic Process Neuron Death Regulation Of Signal Transduction Modulation By Symbiont Of Host I-kappaB Kinase/NF-kappaB Cascade Negative Regulation Of Phosphorylation Regulation Of Signaling Keratinocyte Differentiation Synaptic Growth At Neuromuscular Junction Tryptophan Catabolic Process To Acetyl-CoA Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Collateral Sprouting In Absence Of Injury Regulation Of Phosphorylation Negative Regulation Of Protein Serine/threonine Kinase Activity Epidermal Cell Differentiation Hormone-mediated Signaling Pathway Chemotaxis Negative Regulation Of Canonical Wnt Signaling Pathway Collateral Sprouting Axon Midline Choice Point Recognition Regulation Of Phosphorus Metabolic Process Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Positive Regulation Of B Cell Receptor Signaling Pathway Negative Regulation Of Wnt Signaling Pathway Cellular Metabolic Process Regulation Of Protein Kinase Activity Negative Regulation Of Protein Kinase Activity Negative Regulation Of Catalytic Activity Regulation Of Kinase Activity Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Cellular Protein Metabolic Process Neuron Remodeling Tryptophan Catabolic Process To Kynurenine Skin Development Negative Regulation Of Kinase Activity Kynurenine Metabolic Process Negative Regulation Of Protein Metabolic Process Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Epidermis Development Phosphorylation Regulation Of Cell Cycle Regulation Of B Cell Receptor Signaling Pathway Regulation Of Developmental Growth Adenosine Metabolic Process Negative Regulation Of Transferase Activity Regulation Of Wnt Signaling Pathway Tryptophan Catabolic Process
Tagcloud ?		address approach bioinformatics carried challenging contribute damage discovery efficiently especially genome hlats1 lats1 mutations numerous opportunities powerful predicted projects putative question regulators silico sort support suppressor suppressors understood unprecedented
Tagcloud (Difference) ?		address approach bioinformatics carried challenging contribute damage discovery efficiently especially genome hlats1 lats1 mutations numerous opportunities powerful predicted projects putative question regulators silico sort support suppressor suppressors understood unprecedented
Tagcloud (Intersection) ?