GBE1 and EPHB3

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		GBE1	EPHB3
Gene Name		glucan (1,4-alpha-), branching enzyme 1	EPH receptor B3
Image
Gene Ontology Annotations	Cellular Component	Cytosol Extracellular Vesicular Exosome	Extracellular Region Cytosol Plasma Membrane Integral Component Of Plasma Membrane Dendrite
	Molecular Function	1,4-alpha-glucan Branching Enzyme Activity Hydrolase Activity, Hydrolyzing O-glycosyl Compounds Cation Binding	Ephrin Receptor Activity ATP Binding Axon Guidance Receptor Activity
	Biological Process	Carbohydrate Metabolic Process Glycogen Metabolic Process Glycogen Biosynthetic Process Glucose Metabolic Process Generation Of Precursor Metabolites And Energy Pathogenesis Small Molecule Metabolic Process	Angiogenesis Urogenital System Development Axon Guidance Axonal Fasciculation Cell Migration Peptidyl-tyrosine Phosphorylation Central Nervous System Projection Neuron Axonogenesis Corpus Callosum Development Regulation Of Cell-cell Adhesion Retinal Ganglion Cell Axon Guidance Regulation Of Rac GTPase Activity Substrate Adhesion-dependent Cell Spreading Regulation Of Cdc42 GTPase Activity Protein Autophosphorylation Ephrin Receptor Signaling Pathway Thymus Development Digestive Tract Morphogenesis Regulation Of Axonogenesis Positive Regulation Of Synapse Assembly Palate Development Dendritic Spine Development Dendritic Spine Morphogenesis
Pathways		Glucose metabolism Glycogen synthesis Myoclonic epilepsy of Lafora Glycogen storage diseases Metabolism of carbohydrates	EPHB-mediated forward signaling Ephrin signaling EPH-ephrin mediated repulsion of cells Axon guidance EPH-Ephrin signaling
Drugs
Diseases
GWAS
Protein-Protein Interactions		4 interactors: EPHB3 PGD PRMT6 TRDMT1	9 interactors: CRK EFNB3 FYN GBE1 LNX1 MLLT4 NFRKB RASA1 RYK
Entrez ID		2632	2049
HPRD ID		01985	03502
Ensembl ID		ENSG00000114480	ENSG00000182580
Uniprot IDs		E9PGM4 Q04446 Q59ET0	P54753
PDB IDs		4BZY	3P1I
Enriched GO Terms of Interacting Partners?		D-gluconate Metabolic Process Histone H3-R2 Methylation Pentose-phosphate Shunt, Oxidative Branch Pentose Biosynthetic Process C-5 Methylation Of Cytosine Peptidyl-arginine Methylation, To Asymmetrical-dimethyl Arginine Methylation DNA Methylation On Cytosine Dendritic Spine Morphogenesis Histone H4-R3 Methylation Peptidyl-arginine N-methylation Corpus Callosum Development Dendritic Spine Development Pentose-phosphate Shunt Dendritic Spine Organization Histone Arginine Methylation Retinal Ganglion Cell Axon Guidance Peptidyl-arginine Methylation Glyceraldehyde-3-phosphate Metabolic Process Regulation Of Rac GTPase Activity TRNA Methylation Axonal Fasciculation Regulation Of Cdc42 GTPase Activity Regulation Of Cdc42 Protein Signal Transduction Glucose 6-phosphate Metabolic Process Positive Regulation Of Synapse Assembly Response To Amphetamine NADP Metabolic Process Neuron Recognition Regulation Of Rac Protein Signal Transduction Central Nervous System Projection Neuron Axonogenesis Substrate Adhesion-dependent Cell Spreading	Ephrin Receptor Signaling Pathway Vascular Endothelial Growth Factor Receptor Signaling Pathway Axon Guidance Axonogenesis Axon Development Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Neuron Projection Morphogenesis Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cell Morphogenesis Involved In Differentiation Peptidyl-tyrosine Phosphorylation Neuron Projection Development Cell Projection Morphogenesis Cell Part Morphogenesis Regulation Of Intracellular Signal Transduction Enzyme Linked Receptor Protein Signaling Pathway Cell Development Neuron Development Cell Morphogenesis Neuron Differentiation Cell Projection Organization Locomotion Regulation Of Ras GTPase Activity Regulation Of Cell Shape Movement Of Cell Or Subcellular Component Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Regulation Of Ras Protein Signal Transduction Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Negative Regulation Of Neuron Apoptotic Process Generation Of Neurons Regulation Of Signal Transduction Neurogenesis Regulation Of Small GTPase Mediated Signal Transduction Platelet Activation Negative Regulation Of Neuron Death Axon Choice Point Recognition Establishment Of Endothelial Intestinal Barrier Regulation Of GTPase Activity Cellular Response To Stimulus Positive Regulation Of Intracellular Signal Transduction Neurotrophin TRK Receptor Signaling Pathway Regulation Of Signaling Neurotrophin Signaling Pathway Cell Surface Receptor Signaling Pathway Response To External Stimulus Regulation Of Neuron Apoptotic Process Detection Of Mechanical Stimulus Involved In Sensory Perception Of Pain Phagocytosis Cellular Response To Platelet-derived Growth Factor Stimulus
Tagcloud ?		amylopectin branching cardiomyocyte cardiomyocytes compaction contrary e609x expectations fetal fetalis glycogen gsd hearts hydrops hypertrabeculation lethality manifestation noncompaction osmotic pathogenetic polysaccharide presumably recapitulated recessive stop swelling trabeculation ventricular	ascl2 cdh1 collapse compete corepressor crc demethylase deregulates disabling displaying emt encapsulation engages hdacs incompletely inducers intriguingly invasiveness lsd1 migratory palisading repress roadblock snail1 snail2 stemness tcf7l2 xenotransplants zeb1
Tagcloud (Difference) ?		amylopectin branching cardiomyocyte cardiomyocytes compaction contrary e609x expectations fetal fetalis glycogen gsd hearts hydrops hypertrabeculation lethality manifestation noncompaction osmotic pathogenetic polysaccharide presumably recapitulated recessive stop swelling trabeculation ventricular	ascl2 cdh1 collapse compete corepressor crc demethylase deregulates disabling displaying emt encapsulation engages hdacs incompletely inducers intriguingly invasiveness lsd1 migratory palisading repress roadblock snail1 snail2 stemness tcf7l2 xenotransplants zeb1
Tagcloud (Intersection) ?