GBE1 and PGD

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
HPRD (two hybrid)

		GBE1	PGD
Gene Name		glucan (1,4-alpha-), branching enzyme 1	phosphogluconate dehydrogenase
Image
Gene Ontology Annotations	Cellular Component	Cytosol Extracellular Vesicular Exosome	Nucleus Cytosol Extracellular Vesicular Exosome
	Molecular Function	1,4-alpha-glucan Branching Enzyme Activity Hydrolase Activity, Hydrolyzing O-glycosyl Compounds Cation Binding	Phosphogluconate Dehydrogenase (decarboxylating) Activity NADP Binding
	Biological Process	Carbohydrate Metabolic Process Glycogen Metabolic Process Glycogen Biosynthetic Process Glucose Metabolic Process Generation Of Precursor Metabolites And Energy Pathogenesis Small Molecule Metabolic Process	Carbohydrate Metabolic Process Pentose-phosphate Shunt Pentose-phosphate Shunt, Oxidative Branch Pathogenesis Pentose Biosynthetic Process D-gluconate Metabolic Process Small Molecule Metabolic Process Oxidation-reduction Process
Pathways		Glucose metabolism Glycogen synthesis Myoclonic epilepsy of Lafora Glycogen storage diseases Metabolism of carbohydrates	Myoclonic epilepsy of Lafora Glycogen storage diseases Metabolism of carbohydrates Pentose phosphate pathway (hexose monophosphate shunt)
Drugs
Diseases
GWAS			Hepatocellular carcinoma ( 20676096)
Protein-Protein Interactions		4 interactors: EPHB3 PGD PRMT6 TRDMT1	4 interactors: CDK4 GBE1 LSM8 TERF1
Entrez ID		2632	5226
HPRD ID		01985	01391
Ensembl ID		ENSG00000114480	ENSG00000142657
Uniprot IDs		E9PGM4 Q04446 Q59ET0	P52209
PDB IDs		4BZY	2JKV 4GWG 4GWK
Enriched GO Terms of Interacting Partners?		D-gluconate Metabolic Process Histone H3-R2 Methylation Pentose-phosphate Shunt, Oxidative Branch Pentose Biosynthetic Process C-5 Methylation Of Cytosine Peptidyl-arginine Methylation, To Asymmetrical-dimethyl Arginine Methylation DNA Methylation On Cytosine Dendritic Spine Morphogenesis Histone H4-R3 Methylation Peptidyl-arginine N-methylation Corpus Callosum Development Dendritic Spine Development Pentose-phosphate Shunt Dendritic Spine Organization Histone Arginine Methylation Retinal Ganglion Cell Axon Guidance Peptidyl-arginine Methylation Glyceraldehyde-3-phosphate Metabolic Process Regulation Of Rac GTPase Activity TRNA Methylation Axonal Fasciculation Regulation Of Cdc42 GTPase Activity Regulation Of Cdc42 Protein Signal Transduction Glucose 6-phosphate Metabolic Process Positive Regulation Of Synapse Assembly Response To Amphetamine NADP Metabolic Process Neuron Recognition Regulation Of Rac Protein Signal Transduction Central Nervous System Projection Neuron Axonogenesis Substrate Adhesion-dependent Cell Spreading	Positive Regulation Of Mitotic Cell Cycle Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Telomeric Loop Formation Age-dependent Telomere Shortening Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Process Regulation Of Cell Cycle Phase Transition Telomere Maintenance Via Telomere Shortening Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Negative Regulation Of Telomere Maintenance Via Telomerase Replicative Cell Aging Negative Regulation Of Telomerase Activity Positive Regulation Of Cell Size Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Regulation Of Nuclear Cell Cycle DNA Replication Regulation Of Mitotic Cell Cycle Regulation Of Telomere Maintenance Via Telomerase Cell Division Negative Regulation Of Cell Cycle Positive Regulation Of Microtubule Polymerization Regulation Of Cell Cycle Process Regulation Of Telomerase Activity Response To Drug Regulation Of Telomere Maintenance Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death RNA-dependent DNA Replication Positive Regulation Of Cell Death Negative Regulation Of Cell Cycle Arrest Negative Regulation Of DNA Biosynthetic Process Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Response To Lead Ion Glycogen Biosynthetic Process Response To Hyperoxia Mitotic Cell Cycle Process Regulation Of Microtubule Polymerization Chromatin Organization Telomere Maintenance Via Telomere Lengthening Response To Testosterone Mitotic Cell Cycle Mitotic Spindle Assembly Checkpoint Spindle Assembly Checkpoint Cellular Polysaccharide Biosynthetic Process Mitotic Spindle Checkpoint Positive Regulation Of Mitotic Nuclear Division Negative Regulation Of Chromosome Segregation Polysaccharide Biosynthetic Process
Tagcloud ?		amylopectin branching cardiomyocyte cardiomyocytes compaction contrary e609x expectations fetal fetalis glycogen gsd hearts hydrops hypertrabeculation lethality manifestation noncompaction osmotic pathogenetic polysaccharide presumably recapitulated recessive stop swelling trabeculation ventricular	a2 achieved actions advances bk1 bk2 bk3 bk4 bradykinin characterization detail diverse ep1 ep2 ep3 ep4 exert hypertension pge prostacyclin prostaglandin prostanoid prostanoids remarkable reviewed subtypes thromboxane versatile
Tagcloud (Difference) ?		amylopectin branching cardiomyocyte cardiomyocytes compaction contrary e609x expectations fetal fetalis glycogen gsd hearts hydrops hypertrabeculation lethality manifestation noncompaction osmotic pathogenetic polysaccharide presumably recapitulated recessive stop swelling trabeculation ventricular	a2 achieved actions advances bk1 bk2 bk3 bk4 bradykinin characterization detail diverse ep1 ep2 ep3 ep4 exert hypertension pge prostacyclin prostaglandin prostanoid prostanoids remarkable reviewed subtypes thromboxane versatile
Tagcloud (Intersection) ?