GBE1 and TRDMT1

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		GBE1	TRDMT1
Gene Name		glucan (1,4-alpha-), branching enzyme 1	tRNA aspartic acid methyltransferase 1
Image
Gene Ontology Annotations	Cellular Component	Cytosol Extracellular Vesicular Exosome	Nucleus Cytoplasm
	Molecular Function	1,4-alpha-glucan Branching Enzyme Activity Hydrolase Activity, Hydrolyzing O-glycosyl Compounds Cation Binding	DNA Binding RNA Binding DNA (cytosine-5-)-methyltransferase Activity TRNA Methyltransferase Activity
	Biological Process	Carbohydrate Metabolic Process Glycogen Metabolic Process Glycogen Biosynthetic Process Glucose Metabolic Process Generation Of Precursor Metabolites And Energy Pathogenesis Small Molecule Metabolic Process	Response To Amphetamine TRNA Methylation C-5 Methylation Of Cytosine
Pathways		Glucose metabolism Glycogen synthesis Myoclonic epilepsy of Lafora Glycogen storage diseases Metabolism of carbohydrates
Drugs
Diseases
GWAS
Protein-Protein Interactions		4 interactors: EPHB3 PGD PRMT6 TRDMT1	14 interactors: APP COPS6 DDX24 EEF1A1 GBE1 LRIF1 NFRKB RBM48 SETDB1 SNRPD3 STX1A TBC1D2B UNC119 UTP14A
Entrez ID		2632	1787
HPRD ID		01985	16001
Ensembl ID		ENSG00000114480	ENSG00000107614
Uniprot IDs		E9PGM4 Q04446 Q59ET0	E7EMI8 O14717 Q6ICS7
PDB IDs		4BZY	1G55
Enriched GO Terms of Interacting Partners?		D-gluconate Metabolic Process Histone H3-R2 Methylation Pentose-phosphate Shunt, Oxidative Branch Pentose Biosynthetic Process C-5 Methylation Of Cytosine Peptidyl-arginine Methylation, To Asymmetrical-dimethyl Arginine Methylation DNA Methylation On Cytosine Dendritic Spine Morphogenesis Histone H4-R3 Methylation Peptidyl-arginine N-methylation Corpus Callosum Development Dendritic Spine Development Pentose-phosphate Shunt Dendritic Spine Organization Histone Arginine Methylation Retinal Ganglion Cell Axon Guidance Peptidyl-arginine Methylation Glyceraldehyde-3-phosphate Metabolic Process Regulation Of Rac GTPase Activity TRNA Methylation Axonal Fasciculation Regulation Of Cdc42 GTPase Activity Regulation Of Cdc42 Protein Signal Transduction Glucose 6-phosphate Metabolic Process Positive Regulation Of Synapse Assembly Response To Amphetamine NADP Metabolic Process Neuron Recognition Regulation Of Rac Protein Signal Transduction Central Nervous System Projection Neuron Axonogenesis Substrate Adhesion-dependent Cell Spreading	RNA Metabolic Process Regulation Of Protein Tyrosine Kinase Activity Negative Regulation Of Clathrin-mediated Endocytosis MRNA 3'-end Processing Nucleobase-containing Compound Metabolic Process Negative Regulation Of Caveolin-mediated Endocytosis Synaptic Growth At Neuromuscular Junction Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process RNA 3'-end Processing Collateral Sprouting In Absence Of Injury Cytokinesis, Completion Of Separation Cellular Nitrogen Compound Metabolic Process
Tagcloud ?		amylopectin branching cardiomyocyte cardiomyocytes compaction contrary e609x expectations fetal fetalis glycogen gsd hearts hydrops hypertrabeculation lethality manifestation noncompaction osmotic pathogenetic polysaccharide presumably recapitulated recessive stop swelling trabeculation ventricular	a201g caucasian cpg description dnmt dnmt1 dnmt2 dnmt3a dnmt3b dnmts fisher genotyped gg homozygous hormonal hypermethylation hypomethylation islands loci methylate methyltransferases qpcr rs2228612 snp squared statistics tnm uses wildtype
Tagcloud (Difference) ?		amylopectin branching cardiomyocyte cardiomyocytes compaction contrary e609x expectations fetal fetalis glycogen gsd hearts hydrops hypertrabeculation lethality manifestation noncompaction osmotic pathogenetic polysaccharide presumably recapitulated recessive stop swelling trabeculation ventricular	a201g caucasian cpg description dnmt dnmt1 dnmt2 dnmt3a dnmt3b dnmts fisher genotyped gg homozygous hormonal hypermethylation hypomethylation islands loci methylate methyltransferases qpcr rs2228612 snp squared statistics tnm uses wildtype
Tagcloud (Intersection) ?