GATA6 and CRIP2

Number of citations of the paper that reports this interaction (PMID 12530967)
55

Data Source:
HPRD (in vivo, in vitro)

		GATA6	CRIP2
Gene Name		GATA binding protein 6	cysteine-rich protein 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Transcription Factor Complex	Cell Cortex Extracellular Matrix
	Molecular Function	RNA Polymerase II Core Promoter Sequence-specific DNA Binding Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity RNA Polymerase II Repressing Transcription Factor Binding Chromatin Binding Sequence-specific DNA Binding Transcription Factor Activity RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Transcription Factor Binding Zinc Ion Binding Protein Kinase Binding Transcription Regulatory Region DNA Binding	Zinc Ion Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter In Utero Embryonic Development Liver Development Outflow Tract Septum Morphogenesis Type B Pancreatic Cell Differentiation Pancreatic A Cell Differentiation Transcription From RNA Polymerase II Promoter Phospholipid Metabolic Process Endodermal Cell Fate Determination Blood Coagulation Male Gonad Development Cardiac Muscle Hypertrophy In Response To Stress Negative Regulation Of Transforming Growth Factor Beta1 Production Negative Regulation Of Transforming Growth Factor Beta2 Production Response To Drug Negative Regulation Of Apoptotic Process Response To Estrogen Positive Regulation Of Angiogenesis Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Organ Formation Smooth Muscle Cell Differentiation Positive Regulation Of Cardioblast Differentiation Cardiac Muscle Cell Differentiation Positive Regulation Of Cardiac Muscle Cell Proliferation Lung Saccule Development Clara Cell Differentiation Type II Pneumocyte Differentiation Intestinal Epithelial Cell Differentiation Cardiac Vascular Smooth Muscle Cell Differentiation Response To Growth Factor Positive Regulation Of Cell Cycle Arrest Cellular Response To Gonadotropin Stimulus Cellular Response To Hypoxia Cellular Response To BMP Stimulus	Positive Regulation Of Cell Proliferation Hemopoiesis
Pathways		Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS		Tuberculosis ( 20694014)
Protein-Protein Interactions		7 interactors: CRIP2 EP300 HHEX KLF2 KPNA3 MED1 NKX2-1	17 interactors: APP ATN1 ATP1B1 ATXN1 GADD45G GATA4 GATA6 KLF10 NOTCH3 OSGEP PCYT2 PRKG1 PTPN13 SMN1 SPRY2 SRF TK1
Entrez ID		2627	1397
HPRD ID		09043	03113
Ensembl ID		ENSG00000141448	ENSG00000182809
Uniprot IDs		Q53EU2 Q92908	P52943
PDB IDs			2CU8
Enriched GO Terms of Interacting Partners?		Lung Development Respiratory Tube Development Tube Development Respiratory System Development Positive Regulation Of Transcription From RNA Polymerase II Promoter Epithelium Development Epithelial Cell Differentiation Response To Organic Substance Positive Regulation Of Transcription, DNA-templated Hemopoiesis Positive Regulation Of Macromolecule Biosynthetic Process Branching Morphogenesis Of An Epithelial Tube Positive Regulation Of Gene Expression Thyroid Gland Development Immune System Development Organ Development Positive Regulation Of Cellular Biosynthetic Process Morphogenesis Of A Branching Epithelium Negative Regulation Of Transcription From RNA Polymerase II Promoter Myeloid Cell Differentiation Tissue Development Chordate Embryonic Development Morphogenesis Of A Branching Structure Embryo Development Ending In Birth Or Egg Hatching Regulation Of Transcription From RNA Polymerase II Promoter Erythrocyte Development Response To Hormone Epithelial Tube Branching Involved In Lung Morphogenesis Organ Morphogenesis Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress Immune System Process Anatomical Structure Formation Involved In Morphogenesis Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Lung Epithelial Cell Differentiation Epithelial Tube Morphogenesis Negative Regulation Of Transcription, DNA-templated Lung Cell Differentiation Transcription, DNA-templated Lung Morphogenesis Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Embryo Development Lung Epithelium Development System Development RNA Biosynthetic Process Anatomical Structure Morphogenesis Tube Morphogenesis Embryonic Heart Tube Development Positive Regulation Of Cellular Metabolic Process	Blood Coagulation Hemostasis Multicellular Organismal Development Regulation Of Body Fluid Levels System Development Wound Healing Regulation Of Muscle Contraction Positive Regulation Of Cardioblast Differentiation Developmental Process Response To Wounding Tube Development Organ Development Cardiac Vascular Smooth Muscle Cell Differentiation Anatomical Structure Development RNA Metabolic Process Lung Development Respiratory Tube Development Associative Learning Muscle System Process Developmental Growth Negative Regulation Of Cellular Metabolic Process Respiratory System Development Regulation Of Developmental Growth Cell Fate Commitment Nucleobase-containing Compound Metabolic Process Cardiac Muscle Hypertrophy In Response To Stress Coronary Vasculature Development Cardiac Muscle Cell Differentiation Response To Abiotic Stimulus Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Vascular Smooth Muscle Cell Differentiation Formation Of Primary Germ Layer Intestinal Epithelial Cell Differentiation Cardiocyte Differentiation Relaxation Of Muscle Cellular Response To Gonadotropin Stimulus Digestive Tract Development Cardiac Muscle Hypertrophy Cellular Nitrogen Compound Metabolic Process Learning Cardiac Chamber Development Muscle Hypertrophy Regulation Of Transcription From RNA Polymerase II Promoter Digestive System Development Positive Regulation Of Developmental Growth Positive Regulation Of Cardiac Muscle Cell Proliferation Cell Differentiation Gene Expression Forebrain Development
Tagcloud ?		adaptations backgrounddietary blastocysts compensatory conclusionsfirst ebs emb embryoid endoderm gata4 gestation h3k4me2 h3k9me3 lpd npd offspring pe preimplantation primitive programming propagate resultsemb retain sac stabilised trophectoderm unaltered uterus yolk
Tagcloud (Difference) ?		adaptations backgrounddietary blastocysts compensatory conclusionsfirst ebs emb embryoid endoderm gata4 gestation h3k4me2 h3k9me3 lpd npd offspring pe preimplantation primitive programming propagate resultsemb retain sac stabilised trophectoderm unaltered uterus yolk
Tagcloud (Intersection) ?