GMEB2 and GMEB1

Number of citations of the paper that reports this interaction (PMID 10523663)
14

Data Source:
HPRD (in vitro)

		GMEB2	GMEB1
Gene Name		glucocorticoid modulatory element binding protein 2	glucocorticoid modulatory element binding protein 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm	Nucleus Nucleoplasm Cytoplasm
	Molecular Function	DNA Binding Transcription Coactivator Activity Metal Ion Binding	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Transcription Coactivator Activity Metal Ion Binding
	Biological Process	Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter	Transcription, DNA-templated Regulation Of Transcription, DNA-templated
Pathways
Drugs
Diseases
GWAS		Prostate cancer ( 23535732)
Protein-Protein Interactions		6 interactors: ATXN1 ATXN1L CBFA2T3 CREBBP GMEB1 UBE2I	12 interactors: ATF7IP CASP8 CASP9 CREBBP GMEB2 NCOA2 SMAD1 SMAD3 SNIP1 TRIM55 TRIM63 UBE2I
Entrez ID		26205	10691
HPRD ID		16245	16059
Ensembl ID		ENSG00000101216	ENSG00000162419
Uniprot IDs		Q9UKD1	B1AT47 B2RCN8 Q9Y692
PDB IDs			1OQJ
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Cellular Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Lung Alveolus Development Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process RNA Metabolic Process Positive Regulation Of SUMO Transferase Activity Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Positive Regulation Of Hematopoietic Stem Cell Proliferation N-terminal Peptidyl-lysine Acetylation Regulation Of Metabolic Process Nucleobase-containing Compound Metabolic Process Germ-line Stem Cell Maintenance Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Hematopoietic Stem Cell Proliferation Lung Development Peptidyl-lysine Modification Heterocycle Metabolic Process Respiratory Tube Development Cellular Aromatic Compound Metabolic Process Biosynthetic Process Negative Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Cellular Nitrogen Compound Metabolic Process Respiratory System Development Positive Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway N-terminal Protein Amino Acid Acetylation Positive Regulation Of Transcription, DNA-templated Nitrogen Compound Metabolic Process Granulocyte Differentiation Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Cellular Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia	Cellular Response To Organic Cyclic Compound Production Of MiRNAs Involved In Gene Silencing By MiRNA Gene Silencing By MiRNA Cellular Response To DsRNA Negative Regulation Of Gene Expression Posttranscriptional Gene Silencing Response To Organic Cyclic Compound Regulation Of Gene Expression, Epigenetic Primary MiRNA Processing Gene Silencing By RNA Viral Process SMAD Protein Complex Assembly Response To DsRNA Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Cellular Response To Organic Substance Activation Of Cysteine-type Endopeptidase Activity Response To Cobalt Ion Zymogen Activation Gene Silencing Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cysteine-type Endopeptidase Activity Regulation Of Metabolic Process Positive Regulation Of Endopeptidase Activity Positive Regulation Of Peptidase Activity Positive Regulation Of Metabolic Process Response To Organic Substance Regulation Of Gene Expression Positive Regulation Of Cellular Metabolic Process Cellular Response To Dexamethasone Stimulus Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Negative Regulation Of Transcription, DNA-templated Response To Abiotic Stimulus Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Cysteine-type Endopeptidase Activity Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Response To Dexamethasone Signal Transduction Positive Regulation Of Cartilage Development Protein Processing Embryonic Morphogenesis Signaling Peptidyl-lysine Modification Regulation Of Cellular Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Transcription, DNA-templated Cell Communication Regulation Of RNA Biosynthetic Process
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