GMEB2 and GMEB1

Number of citations of the paper that reports this interaction (PubMedID 10523663)
29

Data Source:
HPRD (in vitro)

		GMEB2	GMEB1
Description		glucocorticoid modulatory element binding protein 2	glucocorticoid modulatory element binding protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytoplasm Cytosol	Chromatin Nucleus Nucleoplasm Cytoplasm
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Identical Protein Binding Sequence-specific DNA Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Identical Protein Binding Sequence-specific DNA Binding Metal Ion Binding Hsp27 Protein Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II	Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases
GWAS		Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Prostate cancer ( 23535732) Refractive error ( 32231278) Reticulocyte count ( 32888494)	Basophil count ( 32888494)
Interacting Genes		20 interacting genes: ATXN1 ATXN1L CBFA2T3 CDC7 CEP19 CREBBP FHL2 GMEB1 LMO2 LMO3 MAP1LC3C MOB1A MXRA8 PIN1 POGZ POU6F2 TRAF3 TTF2 UBE2I ZMYND19	16 interacting genes: ATF7IP CASP8 CASP9 CREBBP DNMT3L GMEB2 MX1 NCOA2 RAD51 SMAD1 SMAD3 SNIP1 SPOP TRIM55 TRIM63 UBE2I
Entrez ID		26205	10691
HPRD ID		16245	16059
Ensembl ID		ENSG00000101216	ENSG00000162419
Uniprot IDs		B4DQS0 Q9UKD1	B1AT47 B2RCN8 Q9Y692
PDB IDs			1OQJ
Enriched GO Terms of Interacting Partners?		Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process POZ Domain Binding Regulation Of RNA Metabolic Process Regulation Of Transcription By RNA Polymerase II Regulation Of Primary Metabolic Process Nucleus Metal Ion Binding Cytoplasm Transcription Factor Binding Double-strand Break Repair Via Homologous Recombination Positive Regulation Of Transcription By RNA Polymerase II BHLH Transcription Factor Binding Postsynaptic Cytosol Recombinational Repair Nucleoplasm Regulation Of Macromolecule Biosynthetic Process Regulation Of Macromolecule Metabolic Process Regulation Of Gene Expression Transcription Coregulator Binding Cis-trans Isomerase Activity SUMO Conjugating Enzyme Activity Hsp27 Protein Binding Establishment Of Glial Blood-brain Barrier Vesicle Targeting, Trans-Golgi To Periciliary Membrane Compartment DNA-binding Transcription Factor Binding Tau Protein Binding Lung Alveolus Development DNA-templated Transcription Positive Regulation Of Nucleobase-containing Compound Metabolic Process Nucleic Acid Metabolic Process Positive Regulation Of Macromolecule Metabolic Process Transcription Corepressor Activity Social Behavior Histone H3K27 Acetyltransferase Activity Atrial Cardiac Muscle Cell Development Susceptibility To T Cell Mediated Cytotoxicity Positive Regulation Of Nuclear Receptor-mediated Glucocorticoid Signaling Pathway Double-strand Break Repair Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Regulation Of Metabolic Process DNA Recombination Negative Regulation Of DNA-templated Transcription Nucleobase-containing Compound Biosynthetic Process Histone H3K18 Acetyltransferase Activity N-terminal Peptidyl-lysine Acetylation DNA Repair Innate Immune Response Activating Cell Surface Receptor Signaling Pathway	Nucleus Transcription Regulator Complex MiRNA Processing Response To Anesthetic Identical Protein Binding Nuclear Receptor Binding Heteromeric SMAD Protein Complex SMAD Protein Complex DEAD/H-box RNA Helicase Binding Response To Cobalt Ion Chromatin Macromolecule Metabolic Process Regulation Of Primary Metabolic Process Co-SMAD Binding Primary MiRNA Processing Regulation Of Metabolic Process I-SMAD Binding Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Execution Phase Of Apoptosis Ubiquitin Protein Ligase Binding Regulation Of Macromolecule Metabolic Process Transcription Coregulator Activity SMAD Protein Signal Transduction Nucleoplasm Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Double-strand Break Repair Nuclear Body Positive Regulation Of Cartilage Development Enzyme Binding Cytoplasm Cellular Response To Radiation DNA Methylation-dependent Constitutive Heterochromatin Formation Negative Regulation Of Cardiac Muscle Hypertrophy Protein-containing Complex Ureteric Bud Development Negative Regulation Of Muscle Hypertrophy Meiosis I Transcription Regulator Inhibitor Activity RNA Polymerase II-specific DNA-binding Transcription Factor Binding Response To External Biotic Stimulus Cytosol Caspase Complex Response To Steroid Hormone Post-translational Protein Modification Chromatin Binding Negative Regulation Of DNA-templated Transcription Transcription Coactivator Binding Negative Regulation Of RNA Biosynthetic Process Mesonephric Epithelium Development Mesonephric Tubule Development
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