GMEB2 and POGZ

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		GMEB2	POGZ
Description		glucocorticoid modulatory element binding protein 2	pogo transposable element derived with ZNF domain
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytoplasm Cytosol	Chromatin Nucleus Nucleoplasm Chromosome Cytoplasm Cytosol Plasma Membrane Ciliary Basal Body
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Identical Protein Binding Sequence-specific DNA Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding	Nucleic Acid Binding DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II	Double-strand Break Repair Via Homologous Recombination DNA Repair DNA Recombination DNA Damage Response Mitotic Sister Chromatid Cohesion Positive Regulation Of Transcription By RNA Polymerase II Cell Division Kinetochore Assembly
Pathways
Drugs
Diseases
GWAS		Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Prostate cancer ( 23535732) Refractive error ( 32231278) Reticulocyte count ( 32888494)	Blood trace element (Cu levels) ( 23720494) Body mass index ( 26426971) Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223) Pulse pressure ( 30578418)
Interacting Genes		20 interacting genes: ATXN1 ATXN1L CBFA2T3 CDC7 CEP19 CREBBP FHL2 GMEB1 LMO2 LMO3 MAP1LC3C MOB1A MXRA8 PIN1 POGZ POU6F2 TRAF3 TTF2 UBE2I ZMYND19	87 interacting genes: A1CF ACTMAP AGR2 ANKRD10 AOC1 APP ATXN1 BANP BOLL C10orf55 CCDC136 CDK6 CERCAM CREB1 CRX DAB1 DAZAP2 DMXL1 DTX2 EID2B EIF3F EYA2 FAM168B FCSK FHL2 FNDC3B FOSB GABPB1 GMEB2 H3-4 HGS HIVEP1 HSF2BP HSPB2 HSPB2-C11orf52 HYI JMJD7 KLHDC7B KLHL26 KRTAP3-2 KRTAP6-2 KRTAP8-1 LITAF MBLAC1 MYO1B NFYA NFYC NHLRC4 NICN1 NRF1 ODAM PFDN5 PIDD1 PLEKHB2 PLIN2 POU2AF1 POU2F1 PRR20A PRR20B PRR20C PRR20D PRR20E QRICH1 RBFOX1 RBPMS RSPH1 SP1 SP3 SP4 SPATA12 SPRYD7 STH SUMO2 TBX19 TCIRG1 TMBIM4 TSC1 UFSP1 VAV2 VEZF1 VGLL3 ZBTB24 ZNF143 ZNF410 ZNF710 ZNF76 ZXDC
Entrez ID		26205	23126
HPRD ID		16245	11445
Ensembl ID		ENSG00000101216	ENSG00000143442
Uniprot IDs		B4DQS0 Q9UKD1	A0A8V8TQ67 Q7Z3K3
PDB IDs			2E72 2N3A 6EMP
Enriched GO Terms of Interacting Partners?		Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process POZ Domain Binding Regulation Of RNA Metabolic Process Regulation Of Transcription By RNA Polymerase II Regulation Of Primary Metabolic Process Nucleus Metal Ion Binding Cytoplasm Transcription Factor Binding Double-strand Break Repair Via Homologous Recombination Positive Regulation Of Transcription By RNA Polymerase II BHLH Transcription Factor Binding Postsynaptic Cytosol Recombinational Repair Nucleoplasm Regulation Of Macromolecule Biosynthetic Process Regulation Of Macromolecule Metabolic Process Regulation Of Gene Expression Transcription Coregulator Binding Cis-trans Isomerase Activity SUMO Conjugating Enzyme Activity Hsp27 Protein Binding Establishment Of Glial Blood-brain Barrier Vesicle Targeting, Trans-Golgi To Periciliary Membrane Compartment DNA-binding Transcription Factor Binding Tau Protein Binding Lung Alveolus Development DNA-templated Transcription Positive Regulation Of Nucleobase-containing Compound Metabolic Process Nucleic Acid Metabolic Process Positive Regulation Of Macromolecule Metabolic Process Transcription Corepressor Activity Social Behavior Histone H3K27 Acetyltransferase Activity Atrial Cardiac Muscle Cell Development Susceptibility To T Cell Mediated Cytotoxicity Positive Regulation Of Nuclear Receptor-mediated Glucocorticoid Signaling Pathway Double-strand Break Repair Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Regulation Of Metabolic Process DNA Recombination Negative Regulation Of DNA-templated Transcription Nucleobase-containing Compound Biosynthetic Process Histone H3K18 Acetyltransferase Activity N-terminal Peptidyl-lysine Acetylation DNA Repair Innate Immune Response Activating Cell Surface Receptor Signaling Pathway	Positive Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Positive Regulation Of RNA Metabolic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of Macromolecule Biosynthetic Process RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Biosynthetic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Protein Binding DNA Binding Positive Regulation Of Macromolecule Metabolic Process Nucleus DNA-binding Transcription Factor Activity Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process RNA Polymerase II Transcription Regulator Complex Protein-DNA Complex DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Positive Regulation Of Metabolic Process Regulation Of Primary Metabolic Process CCAAT-binding Factor Complex Identical Protein Binding Sequence-specific DNA Binding Regulation Of Macromolecule Metabolic Process Sequence-specific Double-stranded DNA Binding Adult Locomotory Behavior
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