GMEB2 and MXRA8

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		GMEB2	MXRA8
Description		glucocorticoid modulatory element binding protein 2	matrix remodeling associated 8
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytoplasm Cytosol	Nucleus Cytoplasm Endoplasmic Reticulum Lumen Plasma Membrane Bicellular Tight Junction Cell Surface Membrane Cell Projection Ciliary Membrane Extracellular Exosome Anchoring Junction
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Identical Protein Binding Sequence-specific DNA Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding	Protein Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II	Cell Adhesion Cell Differentiation Establishment Of Glial Blood-brain Barrier
Pathways			Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation
Drugs
Diseases
GWAS		Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Prostate cancer ( 23535732) Refractive error ( 32231278) Reticulocyte count ( 32888494)	Inflammatory bowel disease ( 28067908) Intraocular pressure ( 29617998) Ulcerative colitis ( 28067908)
Interacting Genes		20 interacting genes: ATXN1 ATXN1L CBFA2T3 CDC7 CEP19 CREBBP FHL2 GMEB1 LMO2 LMO3 MAP1LC3C MOB1A MXRA8 PIN1 POGZ POU6F2 TRAF3 TTF2 UBE2I ZMYND19	6 interacting genes: ANKRD11 CABP2 DTX2 GMEB2 NTAQ1 TTC19
Entrez ID		26205	54587
HPRD ID		16245	11330
Ensembl ID		ENSG00000101216	ENSG00000162576
Uniprot IDs		B4DQS0 Q9UKD1	Q9BRK3
PDB IDs			6JO8
Enriched GO Terms of Interacting Partners?		Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process POZ Domain Binding Regulation Of RNA Metabolic Process Regulation Of Transcription By RNA Polymerase II Regulation Of Primary Metabolic Process Nucleus Metal Ion Binding Cytoplasm Transcription Factor Binding Double-strand Break Repair Via Homologous Recombination Positive Regulation Of Transcription By RNA Polymerase II BHLH Transcription Factor Binding Postsynaptic Cytosol Recombinational Repair Nucleoplasm Regulation Of Macromolecule Biosynthetic Process Regulation Of Macromolecule Metabolic Process Regulation Of Gene Expression Transcription Coregulator Binding Cis-trans Isomerase Activity SUMO Conjugating Enzyme Activity Hsp27 Protein Binding Establishment Of Glial Blood-brain Barrier Vesicle Targeting, Trans-Golgi To Periciliary Membrane Compartment DNA-binding Transcription Factor Binding Tau Protein Binding Lung Alveolus Development DNA-templated Transcription Positive Regulation Of Nucleobase-containing Compound Metabolic Process Nucleic Acid Metabolic Process Positive Regulation Of Macromolecule Metabolic Process Transcription Corepressor Activity Social Behavior Histone H3K27 Acetyltransferase Activity Atrial Cardiac Muscle Cell Development Susceptibility To T Cell Mediated Cytotoxicity Positive Regulation Of Nuclear Receptor-mediated Glucocorticoid Signaling Pathway Double-strand Break Repair Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Regulation Of Metabolic Process DNA Recombination Negative Regulation Of DNA-templated Transcription Nucleobase-containing Compound Biosynthetic Process Histone H3K18 Acetyltransferase Activity N-terminal Peptidyl-lysine Acetylation DNA Repair Innate Immune Response Activating Cell Surface Receptor Signaling Pathway	Protein-N-terminal Asparagine Amidohydrolase Activity Protein-N-terminal Glutamine Amidohydrolase Activity
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