RAB11FIP5 and RAB11A

Number of citations of the paper that reports this interaction (PMID 11495908)
79

Data Source:
HPRD (in vitro, two hybrid, in vivo)

		RAB11FIP5	RAB11A
Gene Name		RAB11 family interacting protein 5 (class I)	RAB11A, member RAS oncogene family
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Membrane Mitochondrial Outer Membrane Early Endosome Golgi Apparatus Microtubule Organizing Center Secretory Granule Transport Vesicle Membrane Early Endosome Membrane Intracellular Membrane-bounded Organelle Recycling Endosome Recycling Endosome Membrane	Spindle Pole Mitochondrion Multivesicular Body Trans-Golgi Network Kinetochore Microtubule Cytosol Plasma Membrane Transport Vesicle Axon Cytoplasmic Vesicle Membrane Phagocytic Vesicle Membrane Cytoplasmic Vesicle Vesicle Cleavage Furrow Protein Complex Phagocytic Vesicle Perinuclear Region Of Cytoplasm Recycling Endosome Recycling Endosome Membrane Extracellular Vesicular Exosome
	Molecular Function	Protein Binding Rab GTPase Binding Gamma-tubulin Binding	GTPase Activity Protein Binding GTP Binding Microtubule Binding GDP Binding Syntaxin Binding Myosin V Binding
	Biological Process	Protein Transport Insulin Secretion Involved In Cellular Response To Glucose Stimulus Regulated Secretory Pathway Cellular Response To Acidic PH Regulation Of Protein Localization To Cell Surface	Cytokinesis Renal Water Homeostasis Water Transport Intracellular Protein Transport Exocytosis Organelle Organization Mitotic Metaphase Plate Congression Positive Regulation Of Epithelial Cell Migration Regulation Of Multivesicular Body Size Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Vesicle-mediated Transport Astral Microtubule Organization Neuron Projection Development Melanosome Transport Rab Protein Signal Transduction Multivesicular Body Assembly Positive Regulation Of Axon Extension Regulation Of Long-term Neuronal Synaptic Plasticity Plasma Membrane To Endosome Transport Regulation Of Protein Transport Establishment Of Vesicle Localization Transmembrane Transport Regulation Of Vesicle-mediated Transport Establishment Of Protein Localization To Organelle Protein Localization To Plasma Membrane Establishment Of Protein Localization To Membrane Mitotic Spindle Assembly Exosomal Secretion
Pathways			Cargo trafficking to the periciliary membrane Organelle biogenesis and maintenance Vasopressin regulates renal water homeostasis via Aquaporins Translocation of GLUT4 to the plasma membrane VxPx cargo-targeting to cilium Assembly of the primary cilium Aquaporin-mediated transport Anchoring of the basal body to the plasma membrane
Drugs
Diseases
GWAS
Protein-Protein Interactions		9 interactors: ARF6 NAPG RAB11A RAB11B RAB11FIP4 RAB14 RAB25 TROVE2 YWHAG	28 interactors: CHMP1B CHMP3 DTNBP1 GDI2 IKBKG KAT2B MYO5A MYO5B OPTN PPP2R1A PPP2R1B PSEN1 PSEN2 PTGIR RAB11FIP1 RAB11FIP2 RAB11FIP3 RAB11FIP4 RAB11FIP5 RAB3IL1 RABGGTB RCHY1 SEC13 STX4 TBXA2R TDP2 WDR44 YWHAG
Entrez ID		26056	8766
HPRD ID		16117	05715
Ensembl ID		ENSG00000135631	ENSG00000103769
Uniprot IDs		Q9BXF6 Q9UFM0	P62491
PDB IDs			1OIV 1OIW 1OIX 1YZK 2D7C 2GZD 2GZH 2HV8 4C4P
Enriched GO Terms of Interacting Partners?		Rab Protein Signal Transduction Cellular Protein Localization Protein Transport Establishment Of Protein Localization Melanosome Transport Pigment Granule Transport Intracellular Protein Transport Establishment Of Melanosome Localization Melanosome Localization Protein Localization Ras Protein Signal Transduction Cellular Pigmentation Small GTPase Mediated Signal Transduction Cellular Localization Vesicle-mediated Transport Regulation Of Protein Localization Intracellular Transport Membrane Organization Regulation Of Vesicle-mediated Transport Pigmentation Intracellular Signal Transduction Establishment Of Localization In Cell Transport Establishment Of Vesicle Localization Endosomal Transport Vesicle Localization Establishment Of Organelle Localization Exocytosis Multivesicular Body Assembly Regulation Of Multivesicular Body Size Phagolysosome Assembly Involved In Apoptotic Cell Clearance Organelle Localization Positive Regulation Of Epithelial Cell Migration Cell Division Cell Projection Organization Signal Transduction Cytokinesis Secretion By Cell Constitutive Secretory Pathway Multivesicular Body Organization Regulation Of Neuron Differentiation Signaling Cell Cycle Cell Communication Pseudopodium Organization Regulation Of Endosome Size Regulation Of Epithelial Cell Migration Secretion Exosomal Secretion Regulation Of Establishment Of Protein Localization	Protein Transport Establishment Of Protein Localization Protein Localization Establishment Of Localization In Cell Cellular Localization Organelle Localization Vesicle-mediated Transport Establishment Of Organelle Localization Establishment Of Vesicle Localization Vesicle Localization Transport Exocytosis Regulation Of Signal Transduction Post-Golgi Vesicle-mediated Transport Membrane Organization Intracellular Transport Regulation Of Signaling Golgi Vesicle Transport Cell Death Death Insulin Secretion Secretion By Cell Insulin Secretion Involved In Cellular Response To Glucose Stimulus Regulation Of Synaptic Transmission Negative Regulation Of Protein Phosphorylation Regulation Of Catalytic Activity Regulated Secretory Pathway Regulation Of Synaptic Plasticity Regulation Of Body Fluid Levels Amyloid Precursor Protein Catabolic Process Cell-cell Signaling Peptide Hormone Secretion Secretion Peptide Secretion Positive Regulation Of Apoptotic Signaling Pathway Negative Regulation Of Phosphorylation Regulation Of Extrinsic Apoptotic Signaling Pathway Signaling Apoptotic Process Cell Cycle Cell Communication Negative Regulation Of Protein Kinase Activity Programmed Cell Death Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Cell Cycle Process Negative Regulation Of Kinase Activity Hormone Secretion Regulation Of Protein Kinase Activity Beta-amyloid Metabolic Process Amyloid Precursor Protein Metabolic Process
Tagcloud ?			c2 compartments displays fip fip1 fip2 fip3 fip5 fips gtpases hela illumination integral lactc2 live membranes microscopy overlap overlapped overlapping pericentriolar phosphatidylserine probe ps recycling structured tubular
Tagcloud (Difference) ?			c2 compartments displays fip fip1 fip2 fip3 fip5 fips gtpases hela illumination integral lactc2 live membranes microscopy overlap overlapped overlapping pericentriolar phosphatidylserine probe ps recycling structured tubular
Tagcloud (Intersection) ?