RAB11FIP5 and RAB25

Number of citations of the paper that reports this interaction (PMID 11481332)
33

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		RAB11FIP5	RAB25
Gene Name		RAB11 family interacting protein 5 (class I)	RAB25, member RAS oncogene family
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Membrane Mitochondrial Outer Membrane Early Endosome Golgi Apparatus Microtubule Organizing Center Secretory Granule Transport Vesicle Membrane Early Endosome Membrane Intracellular Membrane-bounded Organelle Recycling Endosome Recycling Endosome Membrane	Cytoplasmic Membrane-bounded Vesicle Pseudopodium Pseudopodium Membrane Cytoplasmic Vesicle Recycling Endosome Extracellular Vesicular Exosome
	Molecular Function	Protein Binding Rab GTPase Binding Gamma-tubulin Binding	GTPase Activity Protein Binding GTP Binding GDP Binding Myosin V Binding
	Biological Process	Protein Transport Insulin Secretion Involved In Cellular Response To Glucose Stimulus Regulated Secretory Pathway Cellular Response To Acidic PH Regulation Of Protein Localization To Cell Surface	Epithelial Cell Morphogenesis Intracellular Protein Transport Exocytosis Positive Regulation Of Cell Proliferation Positive Regulation Of Epithelial Cell Migration Pseudopodium Organization Melanosome Transport Rab Protein Signal Transduction Regulation Of Vesicle-mediated Transport
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		9 interactors: ARF6 NAPG RAB11A RAB11B RAB11FIP4 RAB14 RAB25 TROVE2 YWHAG	13 interactors: ACVR1 BMPR1B ITGB1 MED31 MYO5B OPTN RAB11FIP1 RAB11FIP2 RAB11FIP3 RAB11FIP5 SMAD4 SMURF2 TGFBR1
Entrez ID		26056	57111
HPRD ID		16117	06698
Ensembl ID		ENSG00000135631	ENSG00000132698
Uniprot IDs		Q9BXF6 Q9UFM0	P57735
PDB IDs			2OIL 3TSO
Enriched GO Terms of Interacting Partners?		Rab Protein Signal Transduction Cellular Protein Localization Protein Transport Establishment Of Protein Localization Melanosome Transport Pigment Granule Transport Intracellular Protein Transport Establishment Of Melanosome Localization Melanosome Localization Protein Localization Ras Protein Signal Transduction Cellular Pigmentation Small GTPase Mediated Signal Transduction Cellular Localization Vesicle-mediated Transport Regulation Of Protein Localization Intracellular Transport Membrane Organization Regulation Of Vesicle-mediated Transport Pigmentation Intracellular Signal Transduction Establishment Of Localization In Cell Transport Establishment Of Vesicle Localization Endosomal Transport Vesicle Localization Establishment Of Organelle Localization Exocytosis Multivesicular Body Assembly Regulation Of Multivesicular Body Size Phagolysosome Assembly Involved In Apoptotic Cell Clearance Organelle Localization Positive Regulation Of Epithelial Cell Migration Cell Division Cell Projection Organization Signal Transduction Cytokinesis Secretion By Cell Constitutive Secretory Pathway Multivesicular Body Organization Regulation Of Neuron Differentiation Signaling Cell Cycle Cell Communication Pseudopodium Organization Regulation Of Endosome Size Regulation Of Epithelial Cell Migration Secretion Exosomal Secretion Regulation Of Establishment Of Protein Localization	Response To Transforming Growth Factor Beta BMP Signaling Pathway Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Transforming Growth Factor Beta Receptor Signaling Pathway Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Cellular Response To Transforming Growth Factor Beta Stimulus Regulation Of Pathway-restricted SMAD Protein Phosphorylation Regulated Secretory Pathway Endocardial Cell Differentiation Insulin Secretion Involved In Cellular Response To Glucose Stimulus Endothelial Cell Activation Response To Growth Factor Positive Regulation Of SMAD Protein Import Into Nucleus Cell Fate Commitment Germ Cell Migration Negative Regulation Of Cell Proliferation Cellular Response To Organic Substance Regulation Of SMAD Protein Import Into Nucleus Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Pathway-restricted SMAD Protein Phosphorylation Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Positive Regulation Of Signal Transduction Mesenchymal Cell Development Endocardium Development Atrioventricular Valve Morphogenesis Pharyngeal System Development Cardiocyte Differentiation Mesenchymal Cell Differentiation Atrioventricular Valve Development Protein Transport Mesoderm Development Vesicle-mediated Transport Establishment Of Protein Localization Cardiac Epithelial To Mesenchymal Transition Enzyme Linked Receptor Protein Signaling Pathway Pattern Specification Process Activin Receptor Signaling Pathway Transcription Initiation From RNA Polymerase II Promoter Ameboidal-type Cell Migration Cellular Localization Renal Water Homeostasis In Utero Embryonic Development Heart Development Gastrulation Regulation Of Cellular Response To Growth Factor Stimulus Heart Valve Morphogenesis Response To Organic Substance Heart Valve Development Cell Cycle Process Mesenchyme Development
Tagcloud ?			acini acquire alpha5beta1 basement cargo clic3 com compartments concert correspondingly drives endosomal endosomes integrin invasiveness matrigel mcf10dcis metalloproteinase mmp mmp14 mt1 opposes organotypic plane plugs predicts recycling trafficking transferred
Tagcloud (Difference) ?			acini acquire alpha5beta1 basement cargo clic3 com compartments concert correspondingly drives endosomal endosomes integrin invasiveness matrigel mcf10dcis metalloproteinase mmp mmp14 mt1 opposes organotypic plane plugs predicts recycling trafficking transferred
Tagcloud (Intersection) ?