NAF1 and RAMAC

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		NAF1	RAMAC
Description		nuclear assembly factor 1 ribonucleoprotein	RNA guanine-7 methyltransferase activating subunit
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Sno(s)RNA-containing Ribonucleoprotein Complex Cytoplasm Ribonucleoprotein Complex	Nucleus MRNA Capping Enzyme Complex MRNA Cap Methyltransferase RNMT:RAMAC Complex
	Molecular Function	RNA Binding Protein Binding Identical Protein Binding Telomerase RNA Binding	RNA Binding Protein Binding Enzyme Activator Activity Molecular Function Activator Activity
	Biological Process	SnoRNA Guided RRNA Pseudouridine Synthesis Box H/ACA SnoRNP Assembly Pseudouridine Synthesis RRNA Processing Protein-RNA Complex Assembly Positive Regulation Of Telomere Maintenance Via Telomerase Ribosome Biogenesis RNA Stabilization Telomerase RNA Stabilization Telomerase RNA Localization To Cajal Body Positive Regulation Of Telomere Maintenance Via Telomere Lengthening Telomerase Holoenzyme Complex Assembly	7-methylguanosine MRNA Capping MRNA Processing RNA 5'-cap (guanine-N7)-methylation
Pathways
Drugs
Diseases
GWAS		Chronotype ( 30696823) Colorectal cancer ( 25023989) Daytime nap ( 33568662) Hair morphology ( 19896111) Leukocyte telomere length ( 31171785 32109421) Lung adenocarcinoma ( 28604730) Lung cancer ( 28604730) TPE interval (recovery after exercise) ( 32386560)
Interacting Genes		26 interacting genes: BOLL CSNK2A1 DAB1 ELOA FAM168A HERPUD2 KRTAP19-3 KRTAP19-7 KRTAP6-1 KRTAP6-2 MAGED1 MED31 MSX2 RAMAC RBFOX2 SCARNA13 SCARNA8 SH3RF1 SNORA74A SNX33 SORBS3 SS18L1 TENT5B TLE5 UBE2I YWHAE	47 interacting genes: AKAP8L BAG4 BPIFA1 C10orf55 CYSRT1 DAB1 DAZAP2 DMRTB1 FAM168B FOXI1 GOLGA2 HNRNPH1 HNRNPK INCA1 KRT15 KRT31 KRT33B KRTAP1-3 KRTAP8-1 LZTS2 MAGED1 MAPK1IP1L NAF1 OXER1 PEA15 PLSCR1 PLSCR4 POU2AF1 PRR3 PSMA3 RBMX RBMY1F RBPMS RHOXF2 RINT1 SF3B4 SNRPC TEKT3 TEKT4 TNS2 TRIM23 TRIM27 TRIM42 UBC USP54 VPS37C WWOX
Entrez ID		92345	83640
HPRD ID		10054	12845
Ensembl ID		ENSG00000145414	ENSG00000169612
Uniprot IDs		Q96HR8	Q9BTL3
PDB IDs		2EQN	5E8J
Enriched GO Terms of Interacting Partners?			Identical Protein Binding Protein Binding Spliceosomal Complex Structural Constituent Of Skin Epidermis RNA Splicing Intermediate Filament Regulation Of RNA Splicing Nucleic Acid Binding Keratin Filament Transcription Coactivator Activity MRNA Splicing, Via Spliceosome MRNA Processing Regulation Of MRNA Splicing, Via Spliceosome CD4 Receptor Binding RNA Splicing, Via Transesterification Reactions RNA Processing Regulation Of MRNA Processing Ribonucleoprotein Complex RNA Binding Positive Regulation Of Apoptotic Signaling Pathway
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