DUSP21 and CPNE7

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		DUSP21	CPNE7
Description		dual specificity phosphatase 21	copine 7
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Mitochondrion Mitochondrial Inner Membrane Mitochondrial Matrix Cytoskeleton Cilium Membrane Motile Cilium Sperm Flagellum Cell Projection Axonemal A Tubule Inner Sheath	Nucleus Cytoplasm Plasma Membrane Membrane Synapse Extracellular Exosome
	Molecular Function	Phosphoprotein Phosphatase Activity Protein Serine/threonine Phosphatase Activity Protein Tyrosine Phosphatase Activity Protein Binding Hydrolase Activity MAP Kinase Tyrosine/serine/threonine Phosphatase Activity	Protein Binding Calcium-dependent Phospholipid Binding Metal Ion Binding
	Biological Process	Flagellated Sperm Motility Peptidyl-tyrosine Dephosphorylation	Lipid Metabolic Process Cellular Response To Calcium Ion
Pathways			Glycerophospholipid biosynthesis
Drugs
Diseases
GWAS			Age at first sexual intercourse ( 27089180) Body mass index ( 29273807) Brain morphology (MOSTest) ( 32665545) Smoking behaviour (cigarette pack-years) ( 30679032)
Interacting Genes		33 interacting genes: APP ATP23 BPIFA1 CPNE7 CTBP2 EPHA3 EPHA5 ERBB3 ERBB4 EYA2 FAAP20 GET4 GORASP2 IGF1R KLHL20 KRT33B KRTAP11-1 MAP2K5 MYO15B OIP5 POU4F3 PTK7 RFX6 RGS2 ROR1 ROR2 SUOX TEX11 TOX3 TRAF1 UBQLN2 USP2 ZMAT1	28 interacting genes: ADAMTSL4 CALCOCO2 CSNK2B DDIT4L DUSP21 EFHC2 GPX7 KRT75 LHX3 MEOX2 NECAB1 OTP PBX4 PICK1 PKLR REL SAXO1 TEPSIN TRIM23 TRIM27 ZFP90 ZMIZ2 ZNF18 ZNF474 ZNF572 ZNF655 ZNF774 ZRANB1
Entrez ID		63904	27132
HPRD ID		06494	05749
Ensembl ID		ENSG00000189037	ENSG00000178773
Uniprot IDs		Q9H596	Q9UBL6
PDB IDs
Enriched GO Terms of Interacting Partners?		Transmembrane Receptor Protein Tyrosine Kinase Activity Protein Tyrosine Kinase Activity Protein Kinase Activity Receptor Complex Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Axon Neuregulin Receptor Activity Kinase Activity Enzyme-linked Receptor Protein Signaling Pathway GPI-linked Ephrin Receptor Activity Peptidyl-tyrosine Phosphorylation Cell Surface Receptor Signaling Pathway Negative Regulation Of Apoptotic Process Coreceptor Activity Regulation Of Extrinsic Apoptotic Signaling Pathway Regulation Of Apoptotic Process Glial Cell Development Negative Regulation Of Programmed Cell Death Regulation Of Programmed Cell Death Ephrin Receptor Activity Transmembrane-ephrin Receptor Activity Cellular Developmental Process Insulin Receptor Binding Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Regulation Of Cell Communication Regulation Of Signaling Neuron Projection Guidance Axon Guidance ERBB2 Signaling Pathway Establishment Of Planar Polarity ATP Binding Epithelial Cell Differentiation Amyloid-beta Complex Apoptotic Process Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Programmed Cell Death Positive Regulation Of Toll Signaling Pathway Cell Death Positive Regulation Of DNA-binding Transcription Factor Activity Heart Development Cranial Nerve Development Establishment Of Planar Polarity Involved In Nephron Morphogenesis Insulin-like Growth Factor Receptor Signaling Pathway Wnt-protein Binding Regulation Of Adenylate Cyclase-inhibiting Adrenergic Receptor Signaling Pathway Sulfite Oxidase Activity Type II Interferon Binding Meiotic Gene Conversion	Metal Ion Binding Zinc Ion Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Regulation Of Transcription By RNA Polymerase II
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