DFNB31 and MYO15A

Number of citations of the paper that reports this interaction (PMID 15590698)
46

Data Source:
HPRD (in vitro, in vivo)

		DFNB31	MYO15A
Gene Name		deafness, autosomal recessive 31	myosin XVA
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Stereocilia Ankle Link Complex Cytoplasm Actin Filament Growth Cone Photoreceptor Connecting Cilium Stereocilium Periciliary Membrane Compartment	Cytoplasm Myosin Complex Stereocilium Extracellular Vesicular Exosome
	Molecular Function	Protein Binding	Motor Activity Actin Binding Calmodulin Binding ATP Binding
	Biological Process	Retina Homeostasis Sensory Perception Of Sound Positive Regulation Of Gene Expression Sensory Perception Of Light Stimulus Inner Ear Receptor Stereocilium Organization	Sensory Perception Of Sound Locomotory Behavior Metabolic Process Inner Ear Morphogenesis
Pathways
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)	Obesity-related traits ( 23251661)
Protein-Protein Interactions		5 interactors: CASK LRP4 LRRC4C MYO15A MYO7A	4 interactors: DFNB31 EPS8 FASLG USP13
Entrez ID		25861	51168
HPRD ID		09718	04049
Ensembl ID		ENSG00000095397	ENSG00000091536
Uniprot IDs		B9EGE6 Q9P202	Q9UKN7
PDB IDs		1UEZ 1UF1 1UFX
Enriched GO Terms of Interacting Partners?		Inner Ear Morphogenesis System Development Embryonic Morphogenesis Ear Morphogenesis Multicellular Organismal Development Anatomical Structure Development Synaptic Growth At Neuromuscular Junction Positive Regulation Of Presynaptic Membrane Organization Sensory Perception Of Sound Regulation Of Axonogenesis Sensory Perception Of Mechanical Stimulus Inner Ear Development Developmental Process Organ Morphogenesis Ear Development Regulation Of Presynaptic Membrane Organization Embryo Development Organ Development Epidermis Development Postsynaptic Membrane Assembly Equilibrioception Presynaptic Membrane Assembly Post-embryonic Organ Morphogenesis Embryonic Organ Morphogenesis Auditory Receptor Cell Stereocilium Organization Presynaptic Membrane Organization Skeletal Muscle Acetylcholine-gated Channel Clustering Extracellular Matrix Organization Extracellular Structure Organization Negative Regulation Of Keratinocyte Proliferation Regulation Of Neuron Projection Development Generation Of Neurons Auditory Receptor Cell Morphogenesis Phagolysosome Assembly Positive Regulation Of Calcium Ion Import Neurogenesis Protein Heterotetramerization Auditory Receptor Cell Development Regulation Of Cell Morphogenesis Regulation Of Cell Projection Organization Embryonic Organ Development Inner Ear Receptor Stereocilium Organization Regulation Of Keratinocyte Proliferation Membrane Assembly Regulation Of Calcium Ion Import Regulation Of Neuron Differentiation Membrane Biogenesis Cell Morphogenesis Involved In Neuron Differentiation Sensory Organ Development Postsynaptic Membrane Organization	Endosomal Lumen Acidification Actin Polymerization-dependent Cell Motility Retinal Cell Programmed Cell Death Necroptotic Signaling Pathway Exit From Mitosis Cellular Chloride Ion Homeostasis Inflammatory Cell Apoptotic Process Behavioral Response To Ethanol Chloride Ion Homeostasis Positive Regulation Of Endothelial Cell Apoptotic Process Rac Protein Signal Transduction Protein K63-linked Deubiquitination T Cell Apoptotic Process Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Inner Ear Receptor Stereocilium Organization Intracellular PH Reduction Barbed-end Actin Filament Capping Actin Crosslink Formation Sensory Organ Development Dendritic Cell Migration PH Reduction Positive Regulation Of ERBB Signaling Pathway Regulation Of Proteolysis Endosome Organization Necroptotic Process Cell Proliferation Regulation Of Endothelial Cell Apoptotic Process
Tagcloud ?		blindness cytoskeletal deaf drosophila dsychronic dysc electrophysiological enlarged expand larvae larval misshapen neuromuscular neurotransmission neurotransmitter pdz potassium presynaptically scaffold slo slowpoke synapse synapses synaptic uncover usher whirlin zone zones
Tagcloud (Difference) ?		blindness cytoskeletal deaf drosophila dsychronic dysc electrophysiological enlarged expand larvae larval misshapen neuromuscular neurotransmission neurotransmitter pdz potassium presynaptically scaffold slo slowpoke synapse synapses synaptic uncover usher whirlin zone zones
Tagcloud (Intersection) ?