KIDINS220

Gene Name		kinase D-interacting substrate, 220kDa
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Late Endosome Cytosol Membrane Integral Component Of Membrane Protein Complex
	Molecular Function	PDZ Domain Binding
	Biological Process	Activation Of MAPKK Activity In Utero Embryonic Development Positive Regulation Of Neuron Projection Development Cytoplasmic Transport Nerve Growth Factor Signaling Pathway Neurotrophin TRK Receptor Signaling Pathway Dendrite Morphogenesis Cellular Response To Nerve Growth Factor Stimulus
Pathways		ARMS-mediated activation Signalling to ERKs Signalling by NGF Prolonged ERK activation events NGF signalling via TRKA from the plasma membrane
Drugs
Diseases
GWAS		Neutrophil count ( 21507922)
Protein-protein Interactions		9 interactors: CDC73 CRKL MOB4 MYC NGFR NTRK1 NTRK2 NTRK3 PRKD1
Entrez ID		57498
HPRD ID		17235
Ensembl ID		ENSG00000134313
Uniprot IDs		Q7Z322 Q9ULH0
PDB IDs
Enriched GO Terms of Interacting Partners?		Cellular Response To Growth Factor Stimulus Response To Growth Factor Enzyme Linked Receptor Protein Signaling Pathway Neurotrophin Signaling Pathway Positive Regulation Of Neuron Projection Development Cellular Response To Organic Substance Positive Regulation Of Cell Projection Organization Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Positive Regulation Of Signal Transduction Positive Regulation Of Neuron Differentiation Regulation Of Cell Proliferation Regulation Of Neuron Projection Development Response To Organic Substance Positive Regulation Of Neurogenesis Regulation Of Cell Differentiation Regulation Of Signal Transduction Circadian Rhythm Negative Regulation Of Cell Death Regulation Of Cell Projection Organization Positive Regulation Of Cell Development Regulation Of Signaling Regulation Of Neuron Differentiation Protein Autophosphorylation Neurotrophin TRK Receptor Signaling Pathway Cell Surface Receptor Signaling Pathway Positive Regulation Of Cellular Protein Metabolic Process Regulation Of MAPK Cascade Positive Regulation Of Protein Metabolic Process Mechanoreceptor Differentiation Regulation Of Protein Metabolic Process Regulation Of Phosphorylation Positive Regulation Of Axonogenesis Regulation Of Neurogenesis Positive Regulation Of Peptidyl-serine Phosphorylation Positive Regulation Of Protein Phosphorylation Rhythmic Process Regulation Of Catalytic Activity Anatomical Structure Morphogenesis Regulation Of Phosphorus Metabolic Process Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of Catalytic Activity Positive Regulation Of Cellular Metabolic Process Regulation Of Cell Death Positive Regulation Of Cell Proliferation Regulation Of Fibroblast Proliferation Regulation Of Cell Development Positive Regulation Of Cell Differentiation Positive Regulation Of Phosphorylation Regulation Of Peptidyl-serine Phosphorylation Positive Regulation Of Protein Modification Process
Tagcloud ?		acts ankyrin arms cdk cdk4 cdks cyclins ephrin g1 hyperphosphorylation interacting nervous neuroblastoma neurotrophin never organizing platform prb primarily prominent regulate repeat rich scaffold slowdown spanning tightly upregulation