ASF1A and CDAN1

Number of citations of the paper that reports this interaction (PMID 22407294)
8

Data Source:
BioGRID (pull down)

		ASF1A	CDAN1
Gene Name		anti-silencing function 1A histone chaperone	codanin 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm Protein Complex	Nucleus Cytoplasm Plasma Membrane Endomembrane System Integral Component Of Membrane
	Molecular Function	Chromatin Binding Protein Binding Histone Binding	Protein Binding
	Biological Process	Osteoblast Differentiation DNA Repair Nucleosome Assembly DNA Replication-dependent Nucleosome Assembly DNA Replication-independent Nucleosome Assembly Transcription, DNA-templated Chromatin Modification Negative Regulation Of Chromatin Silencing Muscle Cell Differentiation	Chromatin Organization Protein Localization Negative Regulation Of DNA Replication Chromatin Assembly
Pathways		DNA Damage/Telomere Stress Induced Senescence Formation of Senescence-Associated Heterochromatin Foci (SAHF) Cellular Senescence
Drugs
Diseases
GWAS		QT interval ( 19305408)	Protein quantitative trait loci ( 18464913)
Protein-Protein Interactions		22 interactors: ASF1B CDAN1 CHAF1A CHAF1B CHEK2 H3F3A HIRA HIST1H3C HIST1H3E HIST1H4F HIST1H4L HIST3H3 HIST4H4 HTATIP2 PAFAH1B2 PRR3 ST13 TAF1 TLK1 TLK2 VPS28 ZDHHC17	2 interactors: ASF1A PDPK1
Entrez ID		25842	146059
HPRD ID		16459	08470
Ensembl ID		ENSG00000111875	ENSG00000140326
Uniprot IDs		Q9Y294	Q8IWY9
PDB IDs		1TEY 2I32 2IIJ 2IO5 3AAD
Enriched GO Terms of Interacting Partners?		DNA Replication-dependent Nucleosome Assembly Chromatin Assembly Chromatin Assembly Or Disassembly Protein-DNA Complex Assembly DNA Packaging Nucleosome Assembly Nucleosome Organization Chromatin Organization DNA Conformation Change Chromosome Organization DNA Methylation On Cytosine Chromatin Silencing At RDNA DNA Replication-independent Nucleosome Assembly Chromatin Silencing Cellular Macromolecular Complex Assembly Cellular Component Assembly Protein Complex Assembly DNA Methylation Negative Regulation Of Gene Expression, Epigenetic DNA Modification Organelle Organization Gene Silencing Histone H4-K20 Demethylation DNA Metabolic Process Negative Regulation Of Megakaryocyte Differentiation Regulation Of Gene Expression, Epigenetic Chromatin Modification Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Hematopoietic Progenitor Cell Differentiation Telomere Maintenance Regulation Of Megakaryocyte Differentiation Negative Regulation Of Biosynthetic Process Cell Cycle Regulation Of Metabolic Process Gene Expression Methylation CENP-A Containing Nucleosome Assembly Regulation Of Hematopoietic Progenitor Cell Differentiation Histone Exchange Histone Lysine Demethylation Histone Demethylation Protein Demethylation Regulation Of Chromatin Assembly Or Disassembly Centromere Complex Assembly Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Demethylation	Negative Regulation Of Chromatin Silencing Negative Regulation Of Cardiac Muscle Cell Apoptotic Process DNA Replication-dependent Nucleosome Assembly Negative Regulation Of Striated Muscle Cell Apoptotic Process Type B Pancreatic Cell Development Positive Regulation Of Gene Expression, Epigenetic Type B Pancreatic Cell Differentiation Hyperosmotic Response Regulation Of Gene Silencing Enteroendocrine Cell Differentiation Positive Regulation Of Establishment Of Protein Localization To Plasma Membrane Negative Regulation Of Toll-like Receptor Signaling Pathway Regulation Of Mast Cell Degranulation Cellular Response To Epidermal Growth Factor Stimulus Positive Regulation Of Protein Localization To Plasma Membrane Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Glandular Epithelial Cell Development Activation Of Protein Kinase B Activity Response To Epidermal Growth Factor Focal Adhesion Assembly Negative Regulation Of Muscle Cell Apoptotic Process DNA Replication-independent Nucleosome Assembly Regulation Of Mast Cell Activation Regulation Of Regulated Secretory Pathway Positive Regulation Of Calcium Ion Transport Into Cytosol Regulation Of Toll-like Receptor Signaling Pathway Regulation Of Establishment Of Protein Localization To Plasma Membrane Columnar/cuboidal Epithelial Cell Development Adherens Junction Assembly Glandular Epithelial Cell Differentiation Peptidyl-threonine Phosphorylation Cell-substrate Junction Assembly Endocrine Pancreas Development Regulation Of Protein Localization To Plasma Membrane Regulation Of Muscle Cell Apoptotic Process Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway T Cell Costimulation Positive Regulation Of Phospholipase Activity Cellular Component Assembly Regulation Of Calcium Ion Transport Into Cytosol Adherens Junction Organization Regulation Of Phospholipase Activity Response To Osmotic Stress Positive Regulation Of Lipase Activity Positive Regulation Of Calcium Ion Transport Calcium-mediated Signaling Pancreas Development Vascular Endothelial Growth Factor Receptor Signaling Pathway Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Tagcloud ?		assembled caf chaperone chaperones dissect divergent enhances experiencing h4 hira histones involves mimetic newly nucleosomes organization phospho phosphorylated pocket restore shuttle stimulating supply tail timely tlk tlks tousled	15q15 anemias attachments bedouin bridges cdai cdas codanin collagens conceivably dyserythropoietic glycosylated inbred internuclear invagination israeli mim neuraxin organelles reconstructed refined searches spongy symbol synapsin tamary ubiquitously underlies
Tagcloud (Difference) ?		assembled caf chaperone chaperones dissect divergent enhances experiencing h4 hira histones involves mimetic newly nucleosomes organization phospho phosphorylated pocket restore shuttle stimulating supply tail timely tlk tlks tousled	15q15 anemias attachments bedouin bridges cdai cdas codanin collagens conceivably dyserythropoietic glycosylated inbred internuclear invagination israeli mim neuraxin organelles reconstructed refined searches spongy symbol synapsin tamary ubiquitously underlies
Tagcloud (Intersection) ?