NIPBL and TRIO

  • Data Source: HiPPIP (Novel)

NIPBL

TRIO

Name NIPBL cohesin loading factor trio Rho guanine nucleotide exchange factor
Structure PDB 6WG3 PDB 1NTY
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Diseases None
GWAS
  • Adverse response to chemotherapy in breast cancer (alopecia) (paclitaxel) ( 24025145 )
  • Antidepressant treatment resistance (number of drugs prescribed) ( 30700811 )
  • Asthma ( 31959851 )
  • Asthma (childhood onset) ( 31036433 )
  • Electroencephalogram traits ( 25387704 )
  • High density lipoprotein cholesterol levels ( 30498476 )
  • Intake of total sugars ( 31005972 )
  • Major depressive disorder ( 27777418 )
  • Paclitaxel-induced neuropathy ( 23776197 )
  • Physiological dysregulation (Mahalanobis distance) ( 32235003 )
  • Response to selenium supplementation (change in plasma selenium concentration) ( 33382417 )
  • Waist circumference ( 28552196 )
Novel Interactors 1 novel interactors: TRIO 5 novel interactors: DAP DNAH5 MARCHF6 NIPBL PRMT7
Interacting Genes 11 interacting genes: CBX5 CDK6 DBN1 DSCR9 HINFP MAP1LC3C PCNA PCNT PRSS23 SP100 SUMO2 13 interacting genes: BLMH CDC42 CDC5L DISC1 DSCR9 EXOC1 FLNA ITSN2 LIMS1 PTK2 PTPRF RAC1 RHOA
Entrez ID 25836 7204
HPRD ID 10560 03537
Ensembl ID ENSG00000164190 ENSG00000038382
Uniprot IDs A0A590UJS4 Q6KC79 O75962
PDB IDs 6WG3 6WGE 7W1M 1NTY 2NZ8 6D8Z 7SJ4
GO Terms Enriched among Interactors