GAD1 and CMTM5

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		GAD1	CMTM5
Gene Name		glutamate decarboxylase 1 (brain, 67kDa)	CKLF-like MARVEL transmembrane domain containing 5
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Intracellular Plasma Membrane Vesicle Membrane Clathrin-sculpted Gamma-aminobutyric Acid Transport Vesicle Membrane	Extracellular Space Integral Component Of Membrane
	Molecular Function	Glutamate Decarboxylase Activity Protein Binding Glutamate Binding Pyridoxal Phosphate Binding Protein Heterodimerization Activity Protein N-terminus Binding	Cytokine Activity
	Biological Process	Glutamate Catabolic Process Glutamate Decarboxylation To Succinate Synaptic Transmission Neurotransmitter Secretion Gamma-aminobutyric Acid Biosynthetic Process Protein-pyridoxal-5-phosphate Linkage Neurotransmitter Biosynthetic Process Response To Drug	Chemotaxis Negative Regulation Of Myoblast Differentiation
Pathways		Neurotransmitter Release Cycle GABA synthesis GABA synthesis, release, reuptake and degradation Transmission across Chemical Synapses
Drugs		Pyridoxal Phosphate L-Glutamic Acid
Diseases
GWAS
Protein-Protein Interactions		9 interactors: AGTRAP CMTM5 GAD2 HAAO PPP2CA PPP2CB PRKACA PRKCE STK3	46 interactors: AACS ACSF2 ALDH18A1 APOA1 ARMC9 C12orf10 CPLX1 CYP1A1 DDA1 FAM114A1 FARS2 GAD1 GAD2 GLTP GOLGA2P10 GTF3C1 KIAA0368 LMO2 MCEE MTERF3 NDRG4 PITPNC1 PLIN3 PPIF PPP2R3C PTPN9 RBFA RMDN2 RNF185 RSRC2 SDCBP SH3GLB1 SHMT2 SNX1 SPATA8 SPG21 SSX3 SUCLA2 SYNE4 TIMM44 TPD52L3 TTPA TUBB TUFM VARS2 ZNF391
Entrez ID		2571	116173
HPRD ID		12011	06986
Ensembl ID		ENSG00000128683	ENSG00000166091
Uniprot IDs		Q8IVA8 Q99259	C9JAI6 Q96DZ9
PDB IDs		2OKJ 3VP6
Enriched GO Terms of Interacting Partners?		Fibroblast Growth Factor Receptor Signaling Pathway Cellular Response To Fibroblast Growth Factor Stimulus Response To Fibroblast Growth Factor Apoptotic Process Programmed Cell Death Cell Death Death Cellular Response To Growth Factor Stimulus Response To Growth Factor Regulation Of MAPK Cascade Regulation Of Peptidyl-tyrosine Phosphorylation Inactivation Of MAPK Activity Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Response To Stimulus Activation Of Phospholipase C Activity Positive Regulation Of Phosphorylation Phosphate-containing Compound Metabolic Process Positive Regulation Of Phospholipase C Activity Regulation Of Intracellular Signal Transduction Enzyme Linked Receptor Protein Signaling Pathway Catabolic Process Nuclear Envelope Organization Regulation Of Cellular Amino Acid Metabolic Process Positive Regulation Of Phospholipase Activity Positive Regulation Of Dense Core Granule Biogenesis Positive Regulation Of Cellular Glucuronidation Negative Regulation Of Intracellular Signal Transduction Regulation Of Protein Phosphorylation Positive Regulation Of Epithelial Cell Migration Negative Regulation Of MAP Kinase Activity Negative Regulation Of Signal Transduction Regulation Of Phospholipase Activity Positive Regulation Of Lipase Activity Positive Regulation Of MAPK Cascade Dicarboxylic Acid Metabolic Process Positive Regulation Of Protein Kinase Activity Response To Inorganic Substance Negative Regulation Of Signaling Positive Regulation Of Kinase Activity Regulation Of Cellular Ketone Metabolic Process Glutamate Decarboxylation To Succinate TRAM-dependent Toll-like Receptor 4 Signaling Pathway Histone H3-T6 Phosphorylation Regulation Of Receptor Activity Peptidyl-serine Phosphorylation Regulation Of Phosphorylation Cellular Amino Acid Catabolic Process Nucleus Organization Signaling Response To Hydrogen Peroxide	Carboxylic Acid Metabolic Process Succinate Metabolic Process Organic Acid Metabolic Process Glutamate Decarboxylation To Succinate Glutamate Metabolic Process Dicarboxylic Acid Metabolic Process Small Molecule Metabolic Process Glutamate Catabolic Process Cellular Amino Acid Metabolic Process Dicarboxylic Acid Catabolic Process Neurotransmitter Biosynthetic Process Response To Nutrient Neurotransmitter Secretion Response To Arsenic-containing Substance Alpha-amino Acid Metabolic Process Neurotransmitter Metabolic Process Cellular Metabolic Process Cellular Amino Acid Biosynthetic Process Response To Drug Regulation Of Neurotransmitter Levels Fatty Acid Metabolic Process Monocarboxylic Acid Metabolic Process Ornithine Biosynthetic Process Regulation Of Proton-transporting ATPase Activity, Rotational Mechanism Succinyl-CoA Pathway Negative Regulation Of Cell Adhesion Molecule Production Negative Regulation Of Establishment Of Blood-brain Barrier L-methylmalonyl-CoA Metabolic Process Dibenzo-p-dioxin Catabolic Process Cofactor Metabolic Process Neurotransmitter Transport Establishment Of Localization In Cell Porphyrin-containing Compound Metabolic Process Valyl-tRNA Aminoacylation Negative Regulation Of Oxidative Phosphorylation Uncoupler Activity Protein-pyridoxal-5-phosphate Linkage Uroporphyrinogen III Biosynthetic Process Negative Regulation Of Interleukin-1 Beta Secretion Regulation Of Establishment Of Blood-brain Barrier
Tagcloud ?		ags aire autoimmune autoimmunity chrna1 copies ds dysregulation euploid fundamental graves hypothyroidism intrathymic klk3 owing pge plp1 predisposition promiscuous restricted sag strikingly thymus thymuses thyroglobulin thyroiditis tolerance trisomy typically	author bio chance chip chosen cyclin d1 discover egfr epithelium her2 ihc insure makes manners next partner pc3 performance plasmid plays prostate regulated relationship stream traditional transduction transfection whether
Tagcloud (Difference) ?		ags aire autoimmune autoimmunity chrna1 copies ds dysregulation euploid fundamental graves hypothyroidism intrathymic klk3 owing pge plp1 predisposition promiscuous restricted sag strikingly thymus thymuses thyroglobulin thyroiditis tolerance trisomy typically	author bio chance chip chosen cyclin d1 discover egfr epithelium her2 ihc insure makes manners next partner pc3 performance plasmid plays prostate regulated relationship stream traditional transduction transfection whether
Tagcloud (Intersection) ?