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GABRA4 and PRKCG
Number of citations of the paper that reports this interaction (PMID
12091471
)
16
Data Source:
BioGRID
(affinity chromatography technology)
HPRD
(in vivo)
GABRA4
PRKCG
Gene Name
gamma-aminobutyric acid (GABA) A receptor, alpha 4
protein kinase C, gamma
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Plasma Membrane
Integral Component Of Plasma Membrane
Cell Junction
Chloride Channel Complex
Postsynaptic Membrane
Nucleus
Cytosol
Plasma Membrane
Cell-cell Junction
Dendrite
Perinuclear Region Of Cytoplasm
Synaptic Membrane
Molecular Function
GABA-A Receptor Activity
Extracellular Ligand-gated Ion Channel Activity
Chloride Channel Activity
Benzodiazepine Receptor Activity
Protein Kinase Activity
Protein Kinase C Activity
Calcium-dependent Protein Kinase C Activity
Protein Serine/threonine/tyrosine Kinase Activity
ATP Binding
Zinc Ion Binding
Biological Process
Transport
Gamma-aminobutyric Acid Signaling Pathway
Synaptic Transmission
Central Nervous System Development
Ion Transmembrane Transport
Transmembrane Transport
Chloride Transmembrane Transport
Regulation Of Response To Drug
Protein Phosphorylation
Signal Transduction
Epidermal Growth Factor Receptor Signaling Pathway
Activation Of Phospholipase C Activity
Synaptic Transmission
Blood Coagulation
Learning Or Memory
Chemosensory Behavior
Fibroblast Growth Factor Receptor Signaling Pathway
Phosphorylation
Platelet Activation
Negative Regulation Of Protein Ubiquitination
Regulation Of Response To Food
Positive Regulation Of Mismatch Repair
Intracellular Signal Transduction
Negative Regulation Of Protein Catabolic Process
Regulation Of Circadian Rhythm
Response To Morphine
Negative Regulation Of Neuron Apoptotic Process
Innate Immune Response
Protein Autophosphorylation
Neurotrophin TRK Receptor Signaling Pathway
Response To Pain
Rhythmic Process
Innervation
Negative Regulation Of Proteasomal Protein Catabolic Process
Pathways
GABA receptor activation
Ion channel transport
GABA A receptor activation
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
Ligand-gated ion channel transport
Orphan transporters
Transmission across Chemical Synapses
Signaling by GPCR
Ca-dependent events
CaM pathway
Phospholipase C-mediated cascade
Signaling by FGFR in disease
Signaling by Wnt
Signaling by EGFRvIII in Cancer
PLCG1 events in ERBB2 signaling
DAP12 signaling
Response to elevated platelet cytosolic Ca2+
G alpha (z) signalling events
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
Signaling by PDGF
Calmodulin induced events
DAP12 interactions
Opioid Signalling
EGFR interacts with phospholipase C-gamma
Signaling by ERBB2
Signaling by EGFR
GPCR downstream signaling
Downstream signal transduction
Calmodulin induced events
WNT5A-dependent internalization of FZD4
Signaling by EGFR in Cancer
Platelet activation, signaling and aggregation
PCP/CE pathway
Transmission across Chemical Synapses
Trafficking of GluR2-containing AMPA receptors
DAG and IP3 signaling
CaM pathway
Downstream signaling of activated FGFR
Disinhibition of SNARE formation
Innate Immune System
Signalling by NGF
PLC beta mediated events
Signaling by Ligand-Responsive EGFR Variants in Cancer
G-protein mediated events
NGF signalling via TRKA from the plasma membrane
Trafficking of AMPA receptors
Signaling by Overexpressed Wild-Type EGFR in Cancer
Signaling by FGFR
beta-catenin independent WNT signaling
PLC-gamma1 signalling
Glutamate Binding, Activation of AMPA Receptors and Synaptic Plasticity
Drugs
Lorazepam
Ethchlorvynol
Temazepam
Butabarbital
Butalbital
Talbutal
Pentobarbital
Clobazam
Meprobamate
Alprazolam
Secobarbital
Metharbital
Chlordiazepoxide
Thiopental
Clorazepate
Midazolam
Flurazepam
Primidone
Oxazepam
Methylphenobarbital
Triazolam
Clonazepam
Phenobarbital
Amobarbital
Aprobarbital
Butethal
Heptabarbital
Hexobarbital
Barbital
Barbituric acid derivative
Flunitrazepam
Bromazepam
Nitrazepam
Diseases
GWAS
Protein-Protein Interactions
3 interactors:
APP
DGAT1
PRKCG
58 interactors:
ADRBK1
AFAP1
ANXA7
APP
ARHGEF25
CASR
CCHCR1
CD5
CDC42
CHAT
CYTH2
DAB2
DDX58
DVL2
EIF4E
EPHB1
EXOC5
GABRA1
GABRA4
GFAP
GJA1
GJA3
GRIA4
GRIN1
GRIN2B
GRIN2D
GRM5
GSK3A
HABP4
HSPA4
IRS1
ITGB2
MARK4
NFE2L2
NOXA1
NRGN
NUMB
PA2G4
PARD3
PARD6A
PARD6B
PDLIM5
PEBP1
PICK1
PNMA1
PPP1R14A
RANBP10
RGS2
SCN3A
SDC2
STXBP1
TIAM1
TOP2A
TRIM5
VTN
YWHAB
YWHAE
YWHAG
Entrez ID
2557
5582
HPRD ID
08839
01502
Ensembl ID
ENSG00000109158
ENSG00000126583
Uniprot IDs
P48169
F5H5C4
P05129
PDB IDs
2E73
2UZP
Enriched GO Terms of Interacting Partners
?
Positive Regulation Of Mismatch Repair
Platelet Activation
Regulation Of Mismatch Repair
Synaptic Growth At Neuromuscular Junction
Collateral Sprouting In Absence Of Injury
Learning Or Memory
Cognition
Collateral Sprouting
Axon Midline Choice Point Recognition
Acylglycerol Acyl-chain Remodeling
Alcohol Metabolic Process
Negative Regulation Of Proteolysis
Smooth Endoplasmic Reticulum Calcium Ion Homeostasis
Negative Regulation Of Protein Processing
Axon Choice Point Recognition
Regulation Of Protein Processing
Blood Coagulation
Hemostasis
Very-low-density Lipoprotein Particle Assembly
Single-organism Behavior
Neuron Remodeling
Chemosensory Behavior
Ion Homeostasis
Fatty Acid Homeostasis
Regulation Of Body Fluid Levels
Phosphate-containing Compound Metabolic Process
Behavior
Wound Healing
Protein-lipid Complex Assembly
Diacylglycerol Metabolic Process
Cellular Copper Ion Homeostasis
Regulation Of Proteolysis
Regulation Of Response To Food
Cell Activation
Response To Wounding
Long-chain Fatty-acyl-CoA Metabolic Process
Copper Ion Homeostasis
Suckling Behavior
Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle
Retinol Metabolic Process
Innate Immune Response
Negative Regulation Of Cellular Protein Metabolic Process
Neuron Maturation
MRNA Polyadenylation
Regulation Of Epidermal Growth Factor-activated Receptor Activity
Chemical Homeostasis
Negative Regulation Of Protein Metabolic Process
Mating Behavior
Innervation
Endoplasmic Reticulum Calcium Ion Homeostasis
Regulation Of Signaling
Regulation Of Cellular Process
Signaling
Nervous System Development
Cell Communication
Cell Surface Receptor Signaling Pathway
Multicellular Organismal Development
Developmental Process
Anatomical Structure Development
Generation Of Neurons
System Development
Neuron Development
Neuron Projection Development
Neurogenesis
Signal Transduction
Positive Regulation Of Transport
Regulation Of Cellular Component Organization
Cell Differentiation
Response To Stimulus
Neuron Projection Morphogenesis
Axonogenesis
Neuron Differentiation
Regulation Of Signal Transduction
Cell Projection Organization
Cellular Response To Stimulus
Axon Development
Glutamate Receptor Signaling Pathway
Cell Morphogenesis Involved In Differentiation
Cell Morphogenesis Involved In Neuron Differentiation
Enzyme Linked Receptor Protein Signaling Pathway
Response To Stress
Cell-cell Signaling
Response To Organic Substance
Regulation Of Phosphorus Metabolic Process
Regulation Of Phosphorylation
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Regulation Of Catalytic Activity
Cell Projection Morphogenesis
Ionotropic Glutamate Receptor Signaling Pathway
Positive Regulation Of Metabolic Process
Cell Part Morphogenesis
Ephrin Receptor Signaling Pathway
Regulation Of Cellular Localization
Cell Morphogenesis
Regulation Of Synaptic Plasticity
Axon Guidance
Positive Regulation Of Catalytic Activity
Neuron-neuron Synaptic Transmission
Transport
Regulation Of Cell Development
Tagcloud
?
apoc2
atp1a3
bckdha
cgb
cgm2
cyp2a
d19s112
d19s116
d19s117
d19s118
d19s119
d19s19
d19s2
d19s37
d19s50
d19s51
d19s54
d19s55
d19s6
d19s62
d19s63
d19s7
d19s8
d19s9
manb
pepd
psg1
pw39
tnnt1
Tagcloud (Difference)
?
apoc2
atp1a3
bckdha
cgb
cgm2
cyp2a
d19s112
d19s116
d19s117
d19s118
d19s119
d19s19
d19s2
d19s37
d19s50
d19s51
d19s54
d19s55
d19s6
d19s62
d19s63
d19s7
d19s8
d19s9
manb
pepd
psg1
pw39
tnnt1
Tagcloud (Intersection)
?