GABRA4

Gene Name		gamma-aminobutyric acid (GABA) A receptor, alpha 4
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Cell Junction Chloride Channel Complex Postsynaptic Membrane
	Molecular Function	GABA-A Receptor Activity Extracellular Ligand-gated Ion Channel Activity Chloride Channel Activity Benzodiazepine Receptor Activity
	Biological Process	Transport Gamma-aminobutyric Acid Signaling Pathway Synaptic Transmission Central Nervous System Development Ion Transmembrane Transport Transmembrane Transport Chloride Transmembrane Transport Regulation Of Response To Drug
Pathways		GABA receptor activation Ion channel transport GABA A receptor activation Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell Ligand-gated ion channel transport Orphan transporters Transmission across Chemical Synapses
Drugs		Lorazepam Ethchlorvynol Temazepam Butabarbital Butalbital Talbutal Pentobarbital Clobazam Meprobamate Alprazolam Secobarbital Metharbital Chlordiazepoxide Thiopental Clorazepate Midazolam Flurazepam Primidone Oxazepam Methylphenobarbital Triazolam Clonazepam Phenobarbital Amobarbital Aprobarbital Butethal Heptabarbital Hexobarbital Barbital Barbituric acid derivative Flunitrazepam Bromazepam Nitrazepam
Diseases
GWAS
Protein-protein Interactions		3 interactors: APP DGAT1 PRKCG
Entrez ID		2557
HPRD ID		08839
Ensembl ID		ENSG00000109158
Uniprot IDs		P48169
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Mismatch Repair Platelet Activation Regulation Of Mismatch Repair Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Learning Or Memory Cognition Collateral Sprouting Axon Midline Choice Point Recognition Acylglycerol Acyl-chain Remodeling Alcohol Metabolic Process Negative Regulation Of Proteolysis Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Negative Regulation Of Protein Processing Axon Choice Point Recognition Regulation Of Protein Processing Blood Coagulation Hemostasis Very-low-density Lipoprotein Particle Assembly Single-organism Behavior Neuron Remodeling Chemosensory Behavior Ion Homeostasis Fatty Acid Homeostasis Regulation Of Body Fluid Levels Phosphate-containing Compound Metabolic Process Behavior Wound Healing Protein-lipid Complex Assembly Diacylglycerol Metabolic Process Cellular Copper Ion Homeostasis Regulation Of Proteolysis Regulation Of Response To Food Cell Activation Response To Wounding Long-chain Fatty-acyl-CoA Metabolic Process Copper Ion Homeostasis Suckling Behavior Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Retinol Metabolic Process Innate Immune Response Negative Regulation Of Cellular Protein Metabolic Process Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Chemical Homeostasis Negative Regulation Of Protein Metabolic Process Mating Behavior Innervation Endoplasmic Reticulum Calcium Ion Homeostasis
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