GABRA3 and SDCBP2

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		GABRA3	SDCBP2
Gene Name		gamma-aminobutyric acid (GABA) A receptor, alpha 3	syndecan binding protein (syntenin) 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Cell Junction Chloride Channel Complex Postsynaptic Membrane	Cytoplasm Plasma Membrane Extracellular Vesicular Exosome
	Molecular Function	GABA-A Receptor Activity Extracellular Ligand-gated Ion Channel Activity Chloride Channel Activity Benzodiazepine Receptor Activity	Protein C-terminus Binding Protein Homodimerization Activity Protein Heterodimerization Activity
	Biological Process	Transport Gamma-aminobutyric Acid Signaling Pathway Synaptic Transmission Ion Transmembrane Transport Transmembrane Transport Chloride Transmembrane Transport	Nervous System Development Intracellular Signal Transduction Intracellular Transport
Pathways		GABA receptor activation Ion channel transport GABA A receptor activation Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell Ligand-gated ion channel transport Orphan transporters Transmission across Chemical Synapses
Drugs		Lorazepam Ethchlorvynol Temazepam Butabarbital Butalbital Talbutal Pentobarbital Clobazam Meprobamate Eszopiclone Alprazolam Secobarbital Zolpidem Metharbital Chlordiazepoxide Adinazolam Thiopental Clorazepate Midazolam Flurazepam Primidone Halazepam Diazepam Oxazepam Methylphenobarbital Triazolam Clonazepam Phenobarbital Zopiclone Estazolam Amobarbital Aprobarbital Butethal Heptabarbital Hexobarbital Barbital Barbituric acid derivative Flunitrazepam Bromazepam Clotiazepam Fludiazepam Prazepam Quazepam Cinolazepam Nitrazepam
Diseases
GWAS
Protein-Protein Interactions		3 interactors: SDCBP2 UBQLN1 UGT2B7	41 interactors: ADAP1 ARF4 BEND7 C11orf57 C1orf35 CT45A3 CT45A5 CTH DPPA2 EIF1AD FAM133A FAM13C FAM9B FBXO28 GABRA3 LGALS14 LGALS2 LYAR NFASC NPM2 NRXN1 NUF2 PAFAH1B3 PRPF38A PRPF40A PRR13 PTMS RNPS1 SDCBP SEC23A SREK1IP1 TDO2 THAP6 TIFA TM4SF1 TNP1 YTHDC1 ZCCHC10 ZCCHC17 ZNF581 ZRSR2
Entrez ID		2556	27111
HPRD ID		02375	18032
Ensembl ID		ENSG00000011677	ENSG00000125775
Uniprot IDs		P34903	Q9H190
PDB IDs
Enriched GO Terms of Interacting Partners?		Flavonoid Biosynthetic Process Flavonoid Glucuronidation Cellular Glucuronidation Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Flavonoid Metabolic Process Androgen Metabolic Process Regulation Of Cellular Response To Oxidative Stress	RNA Splicing MRNA Processing MRNA Metabolic Process RNA Processing Cellular Component Assembly Protein Complex Assembly Involved In Synapse Maturation Fertilization, Exchange Of Chromosomal Proteins Gamma-aminobutyric Acid Receptor Clustering Protein Sulfhydration Protein-pyridoxal-5-phosphate Linkage Via Peptidyl-N6-pyridoxal Phosphate-L-lysine Cellular Nitrogen Compound Metabolic Process Locomotion MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Spliceosomal Complex Assembly Male Pronucleus Assembly Guanylate Kinase-associated Protein Clustering Neuroligin Clustering Protein-pyridoxal-5-phosphate Linkage Transsulfuration Tryptophan Catabolic Process To Acetyl-CoA Gene Expression Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Nitrogen Compound Metabolic Process Gephyrin Clustering Synaptic Vesicle Clustering Hydrogen Sulfide Biosynthetic Process
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