SLC41A1 and KASH5

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SLC41A1	KASH5
Description		solute carrier family 41 member 1	KASH domain containing 5
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Basolateral Plasma Membrane Protein-containing Complex	Chromosome, Telomeric Region Lateral Element Nucleus Nuclear Envelope Nuclear Outer Membrane Chromosome Membrane Meiotic Nuclear Membrane Microtubule Tethering Complex Meiotic Spindle Pole
	Molecular Function	Protein Binding Monoatomic Cation Transmembrane Transporter Activity Magnesium Ion Transmembrane Transporter Activity Transmembrane Transporter Activity Inorganic Cation Transmembrane Transporter Activity Magnesium:sodium Antiporter Activity	Protein Binding Identical Protein Binding Dynein Complex Binding
	Biological Process	Monoatomic Ion Transport Monoatomic Cation Transport Intracellular Magnesium Ion Homeostasis Magnesium Ion Transport Metal Ion Transport Sodium Ion Transmembrane Transport Cellular Response To Magnesium Ion Magnesium Ion Transmembrane Transport	Double-strand Break Repair Via Homologous Recombination Actin Filament Organization Homologous Chromosome Pairing At Meiosis Spermatogenesis Telomere Localization Meiotic Telomere Clustering Oogenesis Spindle Assembly Meiotic Cell Cycle Spindle Localization Chromosome Localization To Nuclear Envelope Involved In Homologous Chromosome Segregation
Pathways		Metal ion SLC transporters
Drugs
Diseases
GWAS		Allergic sensitization ( 30013184) Atrial fibrillation ( 30061737) Body size at age 10 ( 32376654) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Monocyte count ( 27863252 32888494) Parkinson's disease ( 28892059 21738487 19915576) Plateletcrit ( 32888494) Prostate cancer ( 25217961) Prostate-specific antigen levels ( 25434496 23269536) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		32 interacting genes: AMIGO1 AQP6 AVPR2 CD79A CLN5 ELOVL7 ERGIC3 FAM209A FFAR2 FFAR3 GJA5 GJB5 GPR101 GPR152 GPR42 KASH5 LHFPL5 OPRM1 SLC10A1 SLC10A6 SLC13A4 SLC23A2 SSMEM1 SYNDIG1 SYPL2 TAAR9 TBXA2R TLCD4 TMEM237 TMEM248 TMEM31 TRHR	112 interacting genes: ABHD1 ADIPOQ ANKRD46 ATF7 BAG5 BCL2L2 BET1 C14orf180 CCDC120 CCDC87 CDC73 CDKL3 CIB3 CLDN8 CMTM5 CRABP2 CTXN3 CWF19L2 CXCL16 CXCL9 CYBC1 DERL1 DNAJC30 EFNA5 EMD FAM161A FAM241B FAM50B FAM90A1 FATE1 FIS1 FRA10AC1 FTCD FXYD3 GABARAPL2 GALNT2 GIMAP5 GOSR2 GPATCH4 GPR25 HMOX1 ITGAM ITM2B JAGN1 KDM1A LARP1 LAT LENG1 LHFPL5 LMNA LRCH4 MALL MARCHF2 MMP14 MOSPD3 MS4A1 MTX2 NRIP3 NSG1 NTAQ1 OLFM4 PDGFRA PGAP2 PGRMC1 PIGU PLP2 PLPP6 PPP1R18 RIPPLY2 RNF146 RSPH14 RSRC2 RTP2 SENP2 SERP2 SGTA SHMT2 SLC30A2 SLC35B4 SLC41A1 SLC41A2 SLC5A4 SLC61A1 SLN SMCO4 SNAP47 STBD1 STX12 STX5 TCF25 TMEM11 TMEM147 TMEM14C TMEM19 TMEM41A TMEM86A TMPRSS4 TNF TRAF3IP3 TRARG1 TSHZ3 TTC23 UPK1B UPK2 VAMP1 VAMP2 VAMP4 VMA12 VTI1B ZC2HC1C ZFPL1 ZNF250
Entrez ID		254428	147872
HPRD ID		15388	08134
Ensembl ID		ENSG00000133065	ENSG00000161609
Uniprot IDs		B2RMP2 Q8IVJ1	Q8N6L0
PDB IDs			6R2I 6WMF
Enriched GO Terms of Interacting Partners?		Membrane G Protein-coupled Receptor Activity G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Plasma Membrane Positive Regulation Of Acute Inflammatory Response To Non-antigenic Stimulus Positive Regulation Of Vasoconstriction Bile Acid:sodium Symporter Activity Symporter Activity Renal Water Transport Monoatomic Ion Transport Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Regulation Of Vasoconstriction Regulation Of Blood Pressure Sodium Ion Transport Protein Binding Connexin Complex Nitrate Transmembrane Transporter Activity Transmembrane Transport Water Transport Renal System Process System Process Renal Water Retention Positive Regulation Of Blood Pressure Bis(monoacylglycero)phosphate Synthase Activity Positive Regulation Of GTP Binding Vacuolar Lumen Gap Junction Channel Activity Involved In Purkinje Myocyte-ventricular Cardiac Muscle Cell Electrical Coupling Mitral Valve Development Septum Primum Development Gap Junction Channel Activity Involved In Atrial Cardiac Muscle Cell-AV Node Cell Electrical Coupling Gap Junction Atrial Ventricular Junction Remodeling Gap Junction Channel Activity Involved In Bundle Of His Cell-Purkinje Myocyte Electrical Coupling Gap Junction Channel Activity Positive Regulation Of Cell Communication By Chemical Coupling Atrial Cardiac Muscle Cell To AV Node Cell Communication By Electrical Coupling Metal Ion Transport Vasomotion Purkinje Myocyte To Ventricular Cardiac Muscle Cell Communication By Electrical Coupling Regulation Of Purkinje Myocyte Action Potential Positive Regulation Of Acute Inflammatory Response Mucosal Immune Response Organ Or Tissue Specific Immune Response Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Morphine Receptor Activity Negative Regulation Of Wnt Protein Secretion Beta-endorphin Receptor Activity Response To Ethanol Bile Acid And Bile Salt Transport	Membrane SNARE Complex SNAP Receptor Activity Protein Binding Endoplasmic Reticulum Membrane Vesicle Fusion Organelle Fusion Organelle Membrane Fusion Membrane Fusion Endoplasmic Reticulum SNARE Binding Membrane Organization Localization Within Membrane Vesicle Organization Presynaptic Endosome Membrane SNARE Complex Assembly Mitochondrial Outer Membrane Establishment Of Protein Localization To Membrane Golgi Membrane Endosome To Plasma Membrane Protein Transport Positive Regulation Of Neutrophil Activation Regulation Of Cellular Localization Monoatomic Cation Transmembrane Transporter Activity Vesicle-mediated Transport Endomembrane System Establishment Of Protein Localization To Plasma Membrane
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