TFEC and TFE3

Number of citations of the paper that reports this interaction (PMID 8336698)
16

Data Source:
HPRD (in vitro)

		TFEC	TFE3
Gene Name		transcription factor EC	transcription factor binding to IGHM enhancer 3
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm	Nucleus Nucleoplasm Cytoplasm
	Molecular Function	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Transcription Coactivator Activity Transcription Corepressor Activity Protein Dimerization Activity	Sequence-specific DNA Binding Transcription Factor Activity Transcription Regulatory Region DNA Binding Protein Dimerization Activity
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Cellular Response To Heat Negative Regulation Of Nucleic Acid-templated Transcription	Transcription, DNA-templated Humoral Immune Response Regulation Of Osteoclast Differentiation Positive Regulation Of Cell Adhesion Positive Regulation Of Transcription From RNA Polymerase II Promoter
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		8 interactors: DCK DEFB127 HNRNPA1 MITF NAPB TFE3 TFEB ZMAT2	9 interactors: E2F3 HMGB1 MITF SMAD3 SMAD4 SMARCE1 TFEB TFEC YWHAG
Entrez ID		22797	7030
HPRD ID		05294	02439
Ensembl ID		ENSG00000105967	ENSG00000068323
Uniprot IDs		O14948	B4DIA5 P19532 Q5JU74
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Osteoclast Differentiation Regulation Of Myeloid Leukocyte Differentiation Regulation Of Myeloid Cell Differentiation SNARE Complex Disassembly Humoral Immune Response Immune System Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Canonical Wnt Signaling Pathway Involved In Negative Regulation Of Apoptotic Process Pyrimidine Nucleoside Salvage Pyrimidine-containing Compound Salvage Deoxyribonucleoside Monophosphate Biosynthetic Process Nucleobase-containing Compound Metabolic Process Immune Response Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Positive Regulation Of Transcription, DNA-templated Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Purine-containing Compound Salvage Positive Regulation Of Gene Expression RNA Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Nitrogen Compound Metabolic Process	Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Biosynthetic Process SMAD Protein Complex Assembly Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Transforming Growth Factor Beta2 Production Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Transcription, DNA-templated Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Transcription Initiation From RNA Polymerase II Promoter Regulation Of Metabolic Process Transcription, DNA-templated Positive Regulation Of Epithelial To Mesenchymal Transition Negative Regulation Of Gene Expression RNA Biosynthetic Process DNA-templated Transcription, Initiation Positive Regulation Of Intracellular Transport Regulation Of Binding Positive Regulation Of Cellular Metabolic Process Regulation Of Cell Death Negative Regulation Of Transcription From RNA Polymerase II Promoter System Development Positive Regulation Of Stem Cell Differentiation SMAD Protein Signal Transduction Regulation Of Epithelial To Mesenchymal Transition Transcription From RNA Polymerase II Promoter Nucleobase-containing Compound Metabolic Process Multicellular Organismal Development Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process RNA Metabolic Process Somitogenesis Anatomical Structure Development Endoderm Development Positive Regulation Of Transforming Growth Factor Beta3 Production Negative Regulation Of Apoptotic Cell Clearance Positive Regulation Of Cell Proliferation Involved In Heart Valve Morphogenesis Embryonic Pattern Specification Cellular Nitrogen Compound Metabolic Process Regulation Of Intracellular Transport
Tagcloud ?		advantage agonists augment autonomous believed competitive confer conservation define determinants engineered enhance fos hsc hscs intrinsically klf10 majority namely niches osteoclastogenesis prdm16 renewal robust screen spi1 supports surprisingly unexpectedly	aas adopt amphipathic bhlh caf cbp cbp2 cofactor confirming e1a fos fused genesis helical helix immunoprecipitate leucine lz melanocyte melanocytes mi microphthalmia myod parallels pigment potentiated resides vp16 zipper
Tagcloud (Difference) ?		advantage agonists augment autonomous believed competitive confer conservation define determinants engineered enhance hsc hscs intrinsically klf10 majority namely niches osteoclastogenesis prdm16 renewal robust screen spi1 supports surprisingly unexpectedly	aas adopt amphipathic bhlh caf cbp cbp2 cofactor confirming e1a fused genesis helical helix immunoprecipitate leucine lz melanocyte melanocytes mi microphthalmia myod parallels pigment potentiated resides vp16 zipper
Tagcloud (Intersection) ?		fos