ATP6V0A2 and CYTH2

Number of citations of the paper that reports this interaction (PMID 16415858)
91

Data Source:
HPRD (in vivo, in vitro, two hybrid)

		ATP6V0A2	CYTH2
Gene Name		ATPase, H+ transporting, lysosomal V0 subunit a2	cytohesin 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Vacuolar Proton-transporting V-type ATPase, V0 Domain Acrosomal Vesicle Cytoplasm Lysosomal Membrane Plasma Membrane Focal Adhesion Endosome Membrane Integral Component Of Membrane Vacuolar Proton-transporting V-type ATPase Complex Phagocytic Vesicle Membrane	Cytoplasm Trans-Golgi Network Plasma Membrane Membrane
	Molecular Function	Protein Binding Proton-transporting ATPase Activity, Rotational Mechanism ATPase Binding	ARF Guanyl-nucleotide Exchange Factor Activity Protein Binding Lipid Binding Inositol 1,4,5 Trisphosphate Binding
	Biological Process	Cellular Iron Ion Homeostasis Immune Response Vacuolar Acidification Insulin Receptor Signaling Pathway ATP Synthesis Coupled Proton Transport ATP Hydrolysis Coupled Proton Transport Transferrin Transport Interaction With Host Transmembrane Transport Vacuolar Proton-transporting V-type ATPase Complex Assembly Phagosome Maturation	Endocytosis Vesicle-mediated Transport Actin Cytoskeleton Organization Regulation Of Cell Adhesion Regulation Of ARF Protein Signal Transduction Positive Regulation Of GTPase Activity
Pathways		Phagosomal maturation (early endosomal stage) Iron uptake and transport Latent infection of Homo sapiens with Mycobacterium tuberculosis Transferrin endocytosis and recycling Insulin receptor recycling Signaling by Insulin receptor
Drugs
Diseases
GWAS		Adiponectin levels ( 22479202)
Protein-Protein Interactions		1 interactors: CYTH2	21 interactors: ADORA2A APC ARF1 ARF6 ARFGAP1 ARRB1 ARRB2 ATP6V0A2 CCDC120 CUX1 CYTIP DYT10 GNAQ IPCEF1 ITGB2 MAPK6 PNPLA2 PRKCA PRKCB PRKCG TRIM23
Entrez ID		23545	9266
HPRD ID		16521	03925
Ensembl ID		ENSG00000185344	ENSG00000105443
Uniprot IDs		Q9Y487	Q99418
PDB IDs			1PBV 1R8M 1R8Q 1R8S 1S9D
Enriched GO Terms of Interacting Partners?			Blood Coagulation Hemostasis Platelet Activation Regulation Of Body Fluid Levels Wound Healing Cell Activation Response To Wounding Signal Transduction Apoptotic Process Programmed Cell Death Signaling Histone H3-T6 Phosphorylation Cell Death Death Cell Communication Positive Regulation Of Metabolic Process Regulation Of Receptor Internalization Cellular Response To Stimulus Regulation Of Phosphorus Metabolic Process Activation Of Phospholipase C Activity Regulation Of Protein Phosphorylation Response To Stimulus Positive Regulation Of Phospholipase C Activity Regulation Of Endocytosis Response To Stress Negative Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Phospholipase Activity Regulation Of Catalytic Activity Membrane Organization COPI-coated Vesicle Budding COPI Coating Of Golgi Vesicle Regulation Of Phosphorylation Regulation Of Cellular Process Cell Surface Receptor Signaling Pathway Regulation Of Phospholipase Activity G-protein Coupled Receptor Internalization Negative Regulation Of Protein Metabolic Process Positive Regulation Of Lipase Activity Enzyme Linked Receptor Protein Signaling Pathway Golgi Vesicle Transport Protein Localization Golgi Vesicle Budding Positive Regulation Of Cellular Metabolic Process Protein Transport Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Protein Ubiquitination Negative Regulation Of Glucose Transport Vesicle-mediated Transport Desensitization Of G-protein Coupled Receptor Protein Signaling Pathway Establishment Of Protein Localization
Tagcloud ?		0x 1x adamts13 aspm bioinformatic bl chickens col12a1 fowl grm5 interpretations jungle lrp2 obscn plau ppp1ca prkdc resequencing rnf168 sanger sl slv smyth stab2 ubc ubiquitinylation vitiliginous vitiligo xirp1
Tagcloud (Difference) ?		0x 1x adamts13 aspm bioinformatic bl chickens col12a1 fowl grm5 interpretations jungle lrp2 obscn plau ppp1ca prkdc resequencing rnf168 sanger sl slv smyth stab2 ubc ubiquitinylation vitiliginous vitiligo xirp1
Tagcloud (Intersection) ?