GCAT and TEAD1

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		GCAT	TEAD1
Gene Name		glycine C-acetyltransferase	TEA domain family member 1 (SV40 transcriptional enhancer factor)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Mitochondrion	Nucleoplasm Cytoplasm Golgi Apparatus
	Molecular Function	Glycine C-acetyltransferase Activity Pyridoxal Phosphate Binding	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding
	Biological Process	Cellular Amino Acid Metabolic Process Biosynthetic Process L-threonine Catabolic Process To Glycine	Regulation Of Transcription, DNA-templated Transcription Initiation From RNA Polymerase II Promoter Gene Expression Hippo Signaling
Pathways			PPARA activates gene expression Fatty acid, triacylglycerol, and ketone body metabolism Generic Transcription Pathway Metabolism of lipids and lipoproteins YAP1- and WWTR1 (TAZ)-stimulated gene expression Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
Drugs		Pyridoxal Phosphate Glycine
Diseases
GWAS			Height ( 20881960)
Protein-Protein Interactions		3 interactors: MDM2 TDH TEAD1	17 interactors: GCAT HLA-DMB INSR MAX MEF2A MEF2BNB-MEF2B MEF2C MYH7 NCOA1 SRF TBP UBTD1 VGLL1 VGLL2 VGLL4 YAP1 ZDHHC17
Entrez ID		23464	7003
HPRD ID		07602	01802
Ensembl ID		ENSG00000100116	ENSG00000187079
Uniprot IDs		A8K228 O75600	A4FUP2 P28347 Q59EF3
PDB IDs			2HZD 3KYS
Enriched GO Terms of Interacting Partners?		Cellular Response To UV-C Cellular Response To Vitamin B1 Traversing Start Control Point Of Mitotic Cell Cycle Response To Vitamin B1 Response To Ether Positive Regulation Of Stem Cell Maintenance Response To UV-C Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Lateral Mesoderm Development Positive Regulation Of Protein Export From Nucleus Response To Magnesium Ion Cellular Response To Antibiotic Negative Regulation Of Cell Cycle Arrest Notochord Development Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle Cellular Response To Toxic Substance Negative Regulation Of Signal Transduction By P53 Class Mediator Positive Regulation Of Cell Cycle G1/S Phase Transition Regulation Of Stem Cell Maintenance Protein Destabilization Paraxial Mesoderm Development Hippo Signaling Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Cellular Response To Estrogen Stimulus Regulation Of Protein Export From Nucleus	Heart Morphogenesis Transcription, DNA-templated RNA Biosynthetic Process Positive Regulation Of Developmental Growth Embryonic Heart Tube Morphogenesis Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Embryonic Heart Tube Development Platelet Formation Positive Regulation Of Growth Platelet Morphogenesis Biosynthetic Process Cardiac Myofibril Assembly Primary Heart Field Specification Sinoatrial Valve Morphogenesis Regulation Of Synaptic Activity Cellular Response To Trichostatin A RNA Metabolic Process Heart Development Transcription From RNA Polymerase II Promoter Regulation Of Developmental Growth Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Nephron Tubule Epithelial Cell Differentiation Epithelial Cell Proliferation Involved In Renal Tubule Morphogenesis Muscle Cell Fate Determination Gene Expression Striated Muscle Tissue Development Regulation Of RNA Metabolic Process Muscle Tissue Development Positive Regulation Of Macromolecule Biosynthetic Process Cardiac Chamber Development Positive Regulation Of Cell Proliferation In Bone Marrow Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Macrophage Apoptotic Process Positive Regulation Of Behavioral Fear Response Positive Regulation Of Organ Growth Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Tissue Development Ventricular Cardiac Myofibril Assembly Smooth Muscle Cell Differentiation Cardiac Muscle Tissue Development Heart Looping Determination Of Heart Left/right Asymmetry Positive Regulation Of Protein Homodimerization Activity Positive Regulation Of Transcription, DNA-templated Cardiac Muscle Cell Development Embryonic Organ Development
Tagcloud ?			520d 5p biomaterial cd105 combinatorial convert converted dedifferentiation demethylation elavl2 fibroblasts gatad2b hsa ipscs lost microrna mir mscs never pluripotent safely stemness survived transfectants transfection transfections tumorigenicity turned usefulness
Tagcloud (Difference) ?			520d 5p biomaterial cd105 combinatorial convert converted dedifferentiation demethylation elavl2 fibroblasts gatad2b hsa ipscs lost microrna mir mscs never pluripotent safely stemness survived transfectants transfection transfections tumorigenicity turned usefulness
Tagcloud (Intersection) ?