SF3B1 and PLRG1

Number of citations of the paper that reports this interaction (PMID 22365833)
24

Data Source:
BioGRID (two hybrid, two hybrid)

		SF3B1	PLRG1
Gene Name		splicing factor 3b, subunit 1, 155kDa	pleiotropic regulator 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex U12-type Spliceosomal Complex Nuclear Speck Catalytic Step 2 Spliceosome	Nucleus Nucleoplasm DNA Replication Factor A Complex Nuclear Speck Catalytic Step 2 Spliceosome
	Molecular Function	Chromatin Binding Protein Binding Poly(A) RNA Binding	Transcription Corepressor Activity Signal Transducer Activity Protein Binding
	Biological Process	RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome RNA Splicing Anterior/posterior Pattern Specification Gene Expression	MRNA Splicing, Via Spliceosome Signal Transduction RNA Splicing Gene Expression Protein Localization To Nucleus Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of Nucleic Acid-templated Transcription
Pathways		Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Minor Pathway mRNA Splicing - Major Pathway	Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS			Fibrinogen ( 21757653)
Protein-Protein Interactions		24 interactors: APBB1 C11orf58 CALM1 CSNK2A1 DYRK1A ERG IL7R MELK MYC NUDT21 PLRG1 PPP1R8 PRPF40A RBM17 SF3B3 SF3B6 SMAD1 SMAD5 SMAD9 SNIP1 TCERG1 TOP1 UBC WBP4	4 interactors: APP CDC5L SF3B1 ZSCAN1
Entrez ID		23451	5356
HPRD ID		09281	16181
Ensembl ID		ENSG00000115524	ENSG00000171566
Uniprot IDs		A0JLT9 O75533 Q7Z497	O43660
PDB IDs		2F9D 2F9J 2FHO 2PEH 3LQV
Enriched GO Terms of Interacting Partners?		RNA Metabolic Process Gene Expression RNA Processing Nucleobase-containing Compound Metabolic Process Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process RNA Splicing Cellular Nitrogen Compound Metabolic Process MRNA Processing MRNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Transforming Growth Factor Beta Receptor Signaling Pathway Phosphorylation Cellular Metabolic Process Cellular Response To Transforming Growth Factor Beta Stimulus Response To Transforming Growth Factor Beta Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Transcription, DNA-templated Ureteric Bud Development Mesonephric Tubule Development Mesonephric Epithelium Development Mesonephros Development RNA Biosynthetic Process Osteoblast Fate Commitment Mullerian Duct Regression Regulation Of Nitrogen Compound Metabolic Process Kidney Epithelium Development Cellular Response To Growth Factor Stimulus Response To Growth Factor Regulation Of Cell Cycle Phosphate-containing Compound Metabolic Process Intracellular Signal Transduction Regulation Of Gene Expression Cellular Macromolecule Biosynthetic Process BMP Signaling Pathway Macromolecule Biosynthetic Process Midbrain Development Regulation Of RNA Metabolic Process Regulation Of Cell Cycle Process Regulation Of Cell Division Anatomical Structure Regression Signal Transduction By Phosphorylation Transcription From RNA Polymerase II Promoter Cellular Response To BMP Stimulus Enzyme Linked Receptor Protein Signaling Pathway Protein Phosphorylation Kidney Development Rhythmic Process	MRNA Processing MRNA Metabolic Process RNA Processing Synaptic Growth At Neuromuscular Junction RNA Metabolic Process Gene Expression Collateral Sprouting In Absence Of Injury Regulation Of Cell Cycle Phase Transition MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition RNA Splicing Nucleobase-containing Compound Metabolic Process Neuron Remodeling Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Cell Cycle Process Nitrogen Compound Metabolic Process Cellular Copper Ion Homeostasis Copper Ion Homeostasis Suckling Behavior Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Mating Behavior Endoplasmic Reticulum Calcium Ion Homeostasis Neuron Recognition RNA Polyadenylation
Tagcloud ?		binet biology birc3 briefer chinese cll concurrent confounded consecutive descent diverse etiology european fludarabine frequencies germline give ighv insights lymphocytic mutated mutations myd88 notch1 persons predominately stratification tp53 un
Tagcloud (Difference) ?		binet biology birc3 briefer chinese cll concurrent confounded consecutive descent diverse etiology european fludarabine frequencies germline give ighv insights lymphocytic mutated mutations myd88 notch1 persons predominately stratification tp53 un
Tagcloud (Intersection) ?