COPG1 and TAPBP

Number of citations of the paper that reports this interaction (PubMedID 11884415)
0

Data Source:
HPRD (in vivo)

		COPG1	TAPBP
Description		coat protein complex I subunit gamma 1	TAP binding protein
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GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Cytosol Membrane Membrane Coat COPI Vesicle Coat Transport Vesicle COPI-coated Vesicle Membrane Organelle Membrane Cytoplasmic Vesicle	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Phagocytic Vesicle Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane MHC Class I Peptide Loading Complex Tapasin-ERp57 Complex Lumenal Side Of Endoplasmic Reticulum Membrane
	Molecular Function	Structural Molecule Activity Protein Binding	Protein Binding MHC Class I Protein Complex Binding MHC Class I Protein Binding Peptide Antigen Binding Protein Folding Chaperone TAP1 Binding TAP2 Binding Unfolded Protein Binding Molecular Adaptor Activity TAP Complex Binding
	Biological Process	Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Intra-Golgi Vesicle-mediated Transport Protein Secretion Protein Transport Vesicle-mediated Transport Establishment Of Golgi Localization Organelle Transport Along Microtubule	MHC Class Ib Protein Complex Assembly Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Peptide Antigen Assembly With MHC Class I Protein Complex Protein Folding Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Regulation Of Gene Expression Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class I Peptide Antigen Stabilization Regulation Of Protein Complex Stability Protein-containing Complex Assembly
Pathways		COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic	ER-Phagosome pathway Antigen Presentation: Folding, assembly and peptide loading of class I MHC
Drugs		S-(Dimethylarsenic)Cysteine
Diseases			Bare lymphocyte syndrome (BLS) type1
GWAS		Height ( 31562340) Hip circumference adjusted for BMI ( 34021172) Hip index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 26426971 34021172) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 30072576)
Interacting Genes		23 interacting genes: ARCN1 ARF1 CDC42 CFTR COPB1 COPE COPG2 COPZ1 COPZ2 DRD1 FILNC1 H2AX PPBP PTGES3 RHOQ RNF10 SACM1L SNCA SUMO2 TAPBP TMED10 WBP2 WEE2-AS1	9 interacting genes: CALR COPB1 COPG1 COPG2 HLA-A HLA-C TAP1 TAP2 UBC
Entrez ID		22820	6892
HPRD ID		09887	09061
Ensembl ID		ENSG00000181789	ENSG00000231925
Uniprot IDs		Q9Y678	A0A024RCT1 A0A0A0MSV9 A0A0A0MT98 A0A8V8TQC5 O15533
PDB IDs		1R4X	3F8U 6ENY 7QNG 7QPD 7TUE 7TUF 7TUG
Enriched GO Terms of Interacting Partners?		COPI Vesicle Coat COPI-coated Vesicle Membrane Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum COPI-coated Vesicle Vesicle-mediated Transport Transport Vesicle Golgi Membrane Intra-Golgi Vesicle-mediated Transport Golgi Vesicle Transport Endoplasmic Reticulum Membrane Establishment Of Localization In Cell Intracellular Protein Transport Intracellular Transport Establishment Of Protein Localization Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Protein Transport Intracellular Protein Localization GBD Domain Binding Cellular Localization Golgi Apparatus Membrane Coat Cytoplasmic Vesicle Organelle Localization Regulation Of Dopamine Uptake Involved In Synaptic Transmission Positive Regulation Of Transport Glutamatergic Synapse Golgi Localization Golgi-associated Vesicle Membrane Adult Locomotory Behavior Endoplasmic Reticulum-Golgi Intermediate Compartment Synaptic Transmission, Dopaminergic Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Long-term Synaptic Depression Positive Regulation Of Exocytosis Behavioral Response To Cocaine Vesicle-mediated Transport In Synapse Bounding Membrane Of Organelle Secretory Granule Membrane Regulation Of Dopamine Metabolic Process Dopamine Transport Regulation Of Neurotransmitter Uptake Establishment Of Organelle Localization Positive Regulation Of Monoatomic Ion Transmembrane Transport D-glucose Transmembrane Transport Positive Regulation Of Secretion By Cell Positive Regulation Of Filopodium Assembly Monoamine Transport Dopamine Metabolic Process Regulation Of Vesicle-mediated Transport GTPase Activity	MHC Class I Peptide Loading Complex Peptide Antigen Assembly With MHC Class I Protein Complex Endoplasmic Reticulum Membrane Phagocytic Vesicle Membrane Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class I Antigen Processing And Presentation Of Endogenous Antigen Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Peptide Antigen Binding Antigen Processing And Presentation Of Peptide Antigen COPI Vesicle Coat Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class Ib COPI-coated Vesicle Membrane Antigen Processing And Presentation Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class I Via ER Pathway, TAP-dependent Peptide Transmembrane Transporter Activity ABC-type Peptide Antigen Transporter Activity TAP Complex Membrane Coat Lumenal Side Of Endoplasmic Reticulum Membrane Positive Regulation Of Adaptive Immune Response Based On Somatic Recombination Of Immune Receptors Built From Immunoglobulin Superfamily Domains Positive Regulation Of Lymphocyte Mediated Immunity Positive Regulation Of Adaptive Immune Response Intra-Golgi Vesicle-mediated Transport Positive Regulation Of T Cell Mediated Cytotoxicity TAP Binding ABC-type Peptide Transporter Activity TAP1 Binding Regulation Of T Cell Mediated Cytotoxicity Cytosol To Endoplasmic Reticulum Transport Regulation Of Lymphocyte Mediated Immunity Endoplasmic Reticulum Cellular Localization Regulation Of Adaptive Immune Response Based On Somatic Recombination Of Immune Receptors Built From Immunoglobulin Superfamily Domains MHC Class Ib Protein Binding Regulation Of Adaptive Immune Response Positive Regulation Of Leukocyte Mediated Cytotoxicity MHC Protein Binding Positive Regulation Of Cell Killing Positive Regulation Of T Cell Mediated Immunity Protein Transport Intracellular Protein Localization MHC Class I Protein Complex Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Positive Regulation Of Immune Effector Process Golgi Membrane Intracellular Transport Adaptive Immune Response Regulation Of Leukocyte Mediated Cytotoxicity Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class I Via ER Pathway, TAP-independent
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