EEPD1

Description		endonuclease/exonuclease/phosphatase family domain containing 1
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane
	Molecular Function	DNA Binding Catalytic Activity Protein Binding
	Biological Process	DNA Repair Positive Regulation Of Cholesterol Efflux
Pathways		NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux
Drugs
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) Fibrinogen levels ( 26561523 28107422) HDL cholesterol levels ( 32203549) High light scatter reticulocyte count ( 32888494) LDL cholesterol levels ( 32203549) Mean spheric corpuscular volume ( 32888494) Obesity-related traits ( 23251661) Platelet count ( 21507922) Pulse pressure ( 30224653) Refractive error ( 32231278) Reticulocyte count ( 32888494) Schizophrenia ( 30285260)
Interacting Genes		3 interacting genes: APP CRYAA GRIP1
Entrez ID		80820
HPRD ID		13884
Ensembl ID		ENSG00000122547
Uniprot IDs		Q7L9B9
PDB IDs
Enriched GO Terms of Interacting Partners?		Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Regulation Of Response To Calcium Ion Amylin Binding Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Lipoprotein Particle Perikaryon Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Cellular Response To Norepinephrine Stimulus Growth Factor Receptor Binding Main Axon Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Regulation Of Spontaneous Synaptic Transmission Response To Light Stimulus NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Neuron Projection Axon Choice Point Recognition Lens Fiber Cell Morphogenesis Heparan Sulfate Binding Signaling Receptor Activator Activity Positive Regulation Of Neuron Projection Arborization Peptidase Activator Activity Cellular Response To Manganese Ion Neurotransmitter Receptor Transport, Endosome To Postsynaptic Membrane Neurotransmitter Receptor Transport, Endosome To Plasma Membrane Regulation Of Cellular Component Organization Negative Regulation Of Blood Circulation Regulation Of Superoxide Anion Generation Collateral Sprouting Regulation Of Growth Heparan Sulfate Proteoglycan Binding Acetylcholine Receptor Binding
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