JADE2 and ING5

Number of citations of the paper that reports this interaction (PMID 16387653)
126

Data Source:
BioGRID (two hybrid, affinity chromatography technology)

		JADE2	ING5
Gene Name		jade family PHD finger 2	inhibitor of growth family, member 5
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Histone Acetyltransferase Complex Nucleoplasm Extracellular Vesicular Exosome	Nucleus Nucleoplasm MOZ/MORF Histone Acetyltransferase Complex
	Molecular Function	Zinc Ion Binding	Chromatin Binding Protein Binding Zinc Ion Binding Methylated Histone Binding
	Biological Process	Histone H3 Acetylation Histone H4-K5 Acetylation Histone H4-K8 Acetylation Histone H4-K12 Acetylation Histone H4-K16 Acetylation SMAD Protein Signal Transduction	DNA Replication Chromatin Organization Transcription, DNA-templated Protein Acetylation Negative Regulation Of Cell Proliferation Positive Regulation Of Apoptotic Process Histone H3 Acetylation Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Growth Positive Regulation Of Apoptotic Signaling Pathway
Pathways		Chromatin modifying enzymes Chromatin organization HATs acetylate histones	Chromatin modifying enzymes Chromatin organization HATs acetylate histones
Drugs
Diseases
GWAS
Protein-Protein Interactions		8 interactors: GORASP2 HIST3H3 ING4 ING5 PACSIN1 ZBTB3 ZBTB5 ZNF496	34 interactors: APC APLP1 ARFIP2 BARD1 C3orf62 CCDC33 CCDC67 CDCA7L CDKN1A CEP44 EP300 FAM118B GCSH HAP1 HGS HTT ICA1 IKZF3 JADE2 KIAA1377 KRT40 KRTAP10-7 KXD1 MBIP MCM6 MEST NAV2 PCM1 PRMT5 SMARCE1 TADA3 TAF1D TP53 VIM
Entrez ID		23338	84289
HPRD ID		15124	16348
Ensembl ID		ENSG00000043143	ENSG00000168395
Uniprot IDs		B3KPL2 D3DQA3 G3XAA4 Q9NQC1	Q8WYH8
PDB IDs			3C6W
Enriched GO Terms of Interacting Partners?		Histone H3 Acetylation Histone Acetylation Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Protein Acetylation Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Organelle Organization Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Negative Regulation Of Growth Cellular Macromolecule Biosynthetic Process Peptidyl-lysine Modification Macromolecule Biosynthetic Process Histone H4-K12 Acetylation DNA Replication Chromosome Organization DNA Metabolic Process DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator Transcription, DNA-templated DNA Damage Response, Signal Transduction Resulting In Transcription Histone H4-K5 Acetylation Histone H4-K8 Acetylation RNA Biosynthetic Process Membrane Tubulation Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Histone Modification Regulation Of RNA Metabolic Process Biosynthetic Process Regulation Of Gene Expression Synaptic Vesicle Endocytosis Regulation Of Nitrogen Compound Metabolic Process Synaptic Vesicle Recycling	Mitotic Cell Cycle Cell Cycle Process Mitotic Cell Cycle Process Organelle Organization Chromosome Organization Cell Cycle Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Regulation Of Cell Cycle Regulation Of Tubulin Deacetylation Histone Acetylation Mitotic Cell Cycle Phase Transition Internal Peptidyl-lysine Acetylation Cell Cycle Phase Transition Peptidyl-lysine Acetylation Cytoplasmic Microtubule Organization Chromatin Organization Internal Protein Amino Acid Acetylation Protein Acetylation Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Regulation Of Gene Expression Cell Cycle Arrest Histone H3 Acetylation Regulation Of Protein Deacetylation Circadian Rhythm Chromatin Modification Stress-induced Premature Senescence Histone Modification Cell Aging Apoptotic Process Negative Regulation Of Gene Expression Tissue Development Central Nervous System Development Regulation Of Mitotic Cell Cycle Negative Regulation Of Biosynthetic Process Anatomical Structure Development Regulation Of Protein Metabolic Process Mitotic Cell Cycle Arrest Programmed Cell Death Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Intracellular Transport Regulation Of Cellular Localization Regulation Of Cell Cycle Phase Transition Cell Death Death Nervous System Development Epithelium Development Determination Of Adult Lifespan
Tagcloud ?			acetylates acetyllysine bonding bromodomain brpf1 calculate directs discrete energies finger h2a h2ak5ac h2b h3k14ac h4k12ac hat heaf6 histones monocytic moz outline perturbation phd pocket quaternary selects tails titration translationally
Tagcloud (Difference) ?			acetylates acetyllysine bonding bromodomain brpf1 calculate directs discrete energies finger h2a h2ak5ac h2b h3k14ac h4k12ac hat heaf6 histones monocytic moz outline perturbation phd pocket quaternary selects tails titration translationally
Tagcloud (Intersection) ?